Red Blood Cells as a Glucocorticoids Delivery System View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1997

AUTHORS

M. D’Ascenzo , A. Antonelli , L. Chiarantini , U. Mancini , M. Magnani

ABSTRACT

Macrophages are long-lived phagocytes with both cytocidal and microbicidal activity. These cells exist in a relatively quiescent basal state and also in “stimulated” or “activated” states. Activation of macrophages occurs by different stimuli (cytokines, bacterial lipopolysaccharide, etc.) and results in increased production of reactive oxygen metabolites and nitric oxide, increased phagocytic uptake, and release of many cytokines including IL-1, IL-6, TNF-α and growth factors (M-CSF, G-CSF). Upon activation macrophages also release lipid mediators (prostaglandins and leukotrienes) and numerous enzymes (1). More... »

PAGES

81-88

Book

TITLE

Erythrocytes as Drug Carriers in Medicine

ISBN

978-1-4899-0046-3
978-1-4899-0044-9

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4899-0044-9_11

DOI

http://dx.doi.org/10.1007/978-1-4899-0044-9_11

DIMENSIONS

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