Acyl Glucuronides View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1996

AUTHORS

Hildegard Spahn-Langguth , Monika Dahms , Andreas Hermening

ABSTRACT

In general, phase-II metabolites of drugs, such as sulfates, O- or N-glucuronides, were anticipated to be rapidly excreted into urine and bile without exhibiting significant biological/pharmacological activity. However, a few years ago various conjugates were proven to have considerable affinity to pharmacological receptors or to contribute to toxic effects. Today, it is largely accepted that they may be active and/or reactive [Kroemer and Klotz, 1992; Spahn-Langguth and Benet, 1992a, b]. More... »

PAGES

313-28

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4757-9480-9_39

DOI

http://dx.doi.org/10.1007/978-1-4757-9480-9_39

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1018873566

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8794225


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