Nicotine View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1985

AUTHORS

Henry Sershen

ABSTRACT

Nicotine, one of the compounds that alter brain function, has been shown to have diverse actions in the CNS. Although there has been considerable interest in the effects of nicotine and tobacco smoking in man and other species, the mechanisms and sites of action of nicotine in the brain are not clearly understood. It has been shown in many experiments that nicotine can influence behavior. Examples are the facilitatory effect of nicotine on self-stimulation,1 the dose-dependent facilitation of avoidance learning,2 the increased performance of learned tasks, and the decrease of task acquisition.3 Improved memory retention after nicotine administration has been suggested to be related to nicotine’s stimulant properties, altering the arousal state after training,4 and not to direct effects on the rate of protein synthesis. Although nicotine reverses the amnestic effects of cycloheximide treatment,5 reversal of the inhibition of protein synthesis is not involved.6 Nicotine increases the release of several biogenic amines and neuropeptides; release of norepinephrine and hydroxytryptamine is increased in brain homogenates,7 and release from the pituitary of ACTH8 and vasopressin9 is also increased. During fetal development, nicotine may affect brain function and development,10 possibly as a result of decreased protein synthesis.11,12 More... »

PAGES

263-278

Book

TITLE

Alterations of Metabolites in the Nervous System

ISBN

978-1-4757-6742-1
978-1-4757-6740-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4757-6740-7_10

DOI

http://dx.doi.org/10.1007/978-1-4757-6740-7_10

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1053678757


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1701", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/17", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Psychology and Cognitive Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Nathan Kline Institute for Psychiatric Research", 
          "id": "https://www.grid.ac/institutes/grid.250263.0", 
          "name": [
            "Center for Neurochemistry, The Nathan S. Kline Institute for Psychiatric Research, Wards Island, New York\u00a010035, USA"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Sershen", 
        "givenName": "Henry", 
        "id": "sg:person.01002303570.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002303570.20"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0006-8993(79)90578-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001115521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(79)90578-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001115521"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/2111415a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001497567", 
          "https://doi.org/10.1038/2111415a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.2042-7158.1979.tb13435.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001677732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.str.10.5.577", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002498242"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0021-9673(01)80452-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002570294"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/217331a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002570855", 
          "https://doi.org/10.1038/217331a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0163-7258(82)90058-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003377054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0163-7258(82)90058-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003377054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0160-5402(83)90064-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003483380"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01247320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003761983", 
          "https://doi.org/10.1007/bf01247320"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(72)90048-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003822096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(72)90048-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003822096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(79)90469-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006220773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(79)90469-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006220773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jnr.490040202", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008107466"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/03602537808993776", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008783024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.80.11.3536", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008848806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(74)90007-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009315732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(74)90007-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009315732"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1150889", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010624113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1150889", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010624113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01926479", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010835587", 
          "https://doi.org/10.1007/bf01926479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01926479", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010835587", 
          "https://doi.org/10.1007/bf01926479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(74)90015-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012299764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(74)90015-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012299764"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/243199a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013236328", 
          "https://doi.org/10.1038/243199a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(76)90558-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013757261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(76)90558-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013757261"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000241188", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014460073"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(82)90107-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018199941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(82)90107-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018199941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(82)91290-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018418182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(82)91290-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018418182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/jnr.490030503", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019002974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1982.tb08669.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019074141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-2999(73)90240-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020835738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-2999(73)90240-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020835738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(73)90035-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022503637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-8993(73)90035-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022503637"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1476-5381.1971.tb08050.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022726487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.71.5.1852", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023004737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(72)90179-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023261994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(72)90179-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023261994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1471-4159.1983.tb00824.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025642519"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00965094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028677720", 
          "https://doi.org/10.1007/bf00965094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00426913", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030020688", 
          "https://doi.org/10.1007/bf00426913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00426913", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030020688", 
          "https://doi.org/10.1007/bf00426913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.4.1321", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030257071"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000117935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033171753"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(77)90080-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033571198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(77)90080-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033571198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00496056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034135312", 
          "https://doi.org/10.1007/bf00496056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00496056", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034135312", 
          "https://doi.org/10.1007/bf00496056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(73)90196-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034157975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(73)90196-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034157975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000117954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034928475"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.2042-7158.1957.tb12289.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040131045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(70)90135-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041209884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(70)90135-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041209884"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.2042-7158.1965.tb07717.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042543140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(80)90224-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043108792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0024-3205(80)90224-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043108792"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0196-9781(81)80005-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043550996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000117969", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049323231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(78)90040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049878984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(78)90040-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049878984"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3181/00379727-147-38444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050265482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3181/00379727-147-38444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050265482"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00492216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050314386", 
          "https://doi.org/10.1007/bf00492216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00492216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050314386", 
          "https://doi.org/10.1007/bf00492216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/283489a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051670505", 
          "https://doi.org/10.1038/283489a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(81)90176-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053174139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0028-3908(81)90176-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053174139"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm00182a028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055938039"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.163.3863.139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062496092"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.619461", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062635065"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7291998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062645253"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7433991", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062646719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075098439", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076106240", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078103840", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1078564391", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080638874", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1080697516", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081079420", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081108817", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081594341", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1081871460", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082005841", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082012095", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082158781", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082161896", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082181927", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1985", 
    "datePublishedReg": "1985-01-01", 
    "description": "Nicotine, one of the compounds that alter brain function, has been shown to have diverse actions in the CNS. Although there has been considerable interest in the effects of nicotine and tobacco smoking in man and other species, the mechanisms and sites of action of nicotine in the brain are not clearly understood. It has been shown in many experiments that nicotine can influence behavior. Examples are the facilitatory effect of nicotine on self-stimulation,1 the dose-dependent facilitation of avoidance learning,2 the increased performance of learned tasks, and the decrease of task acquisition.3 Improved memory retention after nicotine administration has been suggested to be related to nicotine\u2019s stimulant properties, altering the arousal state after training,4 and not to direct effects on the rate of protein synthesis. Although nicotine reverses the amnestic effects of cycloheximide treatment,5 reversal of the inhibition of protein synthesis is not involved.6 Nicotine increases the release of several biogenic amines and neuropeptides; release of norepinephrine and hydroxytryptamine is increased in brain homogenates,7 and release from the pituitary of ACTH8 and vasopressin9 is also increased. During fetal development, nicotine may affect brain function and development,10 possibly as a result of decreased protein synthesis.11,12", 
    "editor": [
      {
        "familyName": "Lajtha", 
        "givenName": "Abel", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4757-6740-7_10", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4757-6742-1", 
        "978-1-4757-6740-7"
      ], 
      "name": "Alterations of Metabolites in the Nervous System", 
      "type": "Book"
    }, 
    "name": "Nicotine", 
    "pagination": "263-278", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4757-6740-7_10"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ffade6fe85c620b622f7f7e2f0256d376eba1174276e4fcc72c65f3bae104d11"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1053678757"
        ]
      }
    ], 
    "publisher": {
      "location": "Boston, MA", 
      "name": "Springer US", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4757-6740-7_10", 
      "https://app.dimensions.ai/details/publication/pub.1053678757"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T19:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8687_00000092.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4757-6740-7_10"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4757-6740-7_10'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4757-6740-7_10'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4757-6740-7_10'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4757-6740-7_10'


 

This table displays all metadata directly associated to this object as RDF triples.

270 TRIPLES      23 PREDICATES      97 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4757-6740-7_10 schema:about anzsrc-for:17
2 anzsrc-for:1701
3 schema:author N5fa4ecfdb03345239154c818d38697e2
4 schema:citation sg:pub.10.1007/bf00426913
5 sg:pub.10.1007/bf00492216
6 sg:pub.10.1007/bf00496056
7 sg:pub.10.1007/bf00965094
8 sg:pub.10.1007/bf01247320
9 sg:pub.10.1007/bf01926479
10 sg:pub.10.1038/2111415a0
11 sg:pub.10.1038/217331a0
12 sg:pub.10.1038/243199a0
13 sg:pub.10.1038/283489a0
14 https://app.dimensions.ai/details/publication/pub.1075098439
15 https://app.dimensions.ai/details/publication/pub.1076106240
16 https://app.dimensions.ai/details/publication/pub.1078103840
17 https://app.dimensions.ai/details/publication/pub.1078564391
18 https://app.dimensions.ai/details/publication/pub.1080638874
19 https://app.dimensions.ai/details/publication/pub.1080697516
20 https://app.dimensions.ai/details/publication/pub.1081079420
21 https://app.dimensions.ai/details/publication/pub.1081108817
22 https://app.dimensions.ai/details/publication/pub.1081594341
23 https://app.dimensions.ai/details/publication/pub.1081871460
24 https://app.dimensions.ai/details/publication/pub.1082005841
25 https://app.dimensions.ai/details/publication/pub.1082012095
26 https://app.dimensions.ai/details/publication/pub.1082158781
27 https://app.dimensions.ai/details/publication/pub.1082161896
28 https://app.dimensions.ai/details/publication/pub.1082181927
29 https://doi.org/10.1002/jnr.490030503
30 https://doi.org/10.1002/jnr.490040202
31 https://doi.org/10.1016/0006-2952(70)90135-8
32 https://doi.org/10.1016/0006-2952(72)90179-7
33 https://doi.org/10.1016/0006-2952(73)90196-2
34 https://doi.org/10.1016/0006-2952(77)90080-6
35 https://doi.org/10.1016/0006-2952(78)90040-0
36 https://doi.org/10.1016/0006-8993(73)90035-8
37 https://doi.org/10.1016/0006-8993(76)90558-8
38 https://doi.org/10.1016/0006-8993(79)90578-x
39 https://doi.org/10.1016/0006-8993(82)91290-2
40 https://doi.org/10.1016/0014-2999(73)90240-9
41 https://doi.org/10.1016/0024-3205(79)90469-7
42 https://doi.org/10.1016/0024-3205(80)90224-6
43 https://doi.org/10.1016/0028-3908(72)90048-2
44 https://doi.org/10.1016/0028-3908(74)90007-0
45 https://doi.org/10.1016/0028-3908(74)90015-x
46 https://doi.org/10.1016/0028-3908(81)90176-3
47 https://doi.org/10.1016/0028-3908(82)90107-1
48 https://doi.org/10.1016/0160-5402(83)90064-5
49 https://doi.org/10.1016/0163-7258(82)90058-4
50 https://doi.org/10.1016/s0021-9673(01)80452-0
51 https://doi.org/10.1016/s0196-9781(81)80005-8
52 https://doi.org/10.1021/jm00182a028
53 https://doi.org/10.1042/bj1150889
54 https://doi.org/10.1073/pnas.71.5.1852
55 https://doi.org/10.1073/pnas.79.4.1321
56 https://doi.org/10.1073/pnas.80.11.3536
57 https://doi.org/10.1111/j.1471-4159.1982.tb08669.x
58 https://doi.org/10.1111/j.1471-4159.1983.tb00824.x
59 https://doi.org/10.1111/j.1476-5381.1971.tb08050.x
60 https://doi.org/10.1111/j.2042-7158.1957.tb12289.x
61 https://doi.org/10.1111/j.2042-7158.1965.tb07717.x
62 https://doi.org/10.1111/j.2042-7158.1979.tb13435.x
63 https://doi.org/10.1126/science.163.3863.139
64 https://doi.org/10.1126/science.619461
65 https://doi.org/10.1126/science.7291998
66 https://doi.org/10.1126/science.7433991
67 https://doi.org/10.1159/000117935
68 https://doi.org/10.1159/000117954
69 https://doi.org/10.1159/000117969
70 https://doi.org/10.1159/000241188
71 https://doi.org/10.1161/01.str.10.5.577
72 https://doi.org/10.3109/03602537808993776
73 https://doi.org/10.3181/00379727-147-38444
74 schema:datePublished 1985
75 schema:datePublishedReg 1985-01-01
76 schema:description Nicotine, one of the compounds that alter brain function, has been shown to have diverse actions in the CNS. Although there has been considerable interest in the effects of nicotine and tobacco smoking in man and other species, the mechanisms and sites of action of nicotine in the brain are not clearly understood. It has been shown in many experiments that nicotine can influence behavior. Examples are the facilitatory effect of nicotine on self-stimulation,1 the dose-dependent facilitation of avoidance learning,2 the increased performance of learned tasks, and the decrease of task acquisition.3 Improved memory retention after nicotine administration has been suggested to be related to nicotine’s stimulant properties, altering the arousal state after training,4 and not to direct effects on the rate of protein synthesis. Although nicotine reverses the amnestic effects of cycloheximide treatment,5 reversal of the inhibition of protein synthesis is not involved.6 Nicotine increases the release of several biogenic amines and neuropeptides; release of norepinephrine and hydroxytryptamine is increased in brain homogenates,7 and release from the pituitary of ACTH8 and vasopressin9 is also increased. During fetal development, nicotine may affect brain function and development,10 possibly as a result of decreased protein synthesis.11,12
77 schema:editor N2aa71a2ca7e649ee9eca55301917b2c6
78 schema:genre chapter
79 schema:inLanguage en
80 schema:isAccessibleForFree false
81 schema:isPartOf Nc566d39bbe7e4aac81c0c63d2413cf40
82 schema:name Nicotine
83 schema:pagination 263-278
84 schema:productId N218cecbcd51645e1a669e0c4c613dd22
85 N568535a8291d4bbf81e0ea060248957a
86 N8138b1d66e534aa887659b0566844f90
87 schema:publisher Nd8aa93b35380410c90412ce7523572d4
88 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053678757
89 https://doi.org/10.1007/978-1-4757-6740-7_10
90 schema:sdDatePublished 2019-04-15T19:56
91 schema:sdLicense https://scigraph.springernature.com/explorer/license/
92 schema:sdPublisher Ndc80881a503a4f7da49fba5301987ed3
93 schema:url http://link.springer.com/10.1007/978-1-4757-6740-7_10
94 sgo:license sg:explorer/license/
95 sgo:sdDataset chapters
96 rdf:type schema:Chapter
97 N218cecbcd51645e1a669e0c4c613dd22 schema:name doi
98 schema:value 10.1007/978-1-4757-6740-7_10
99 rdf:type schema:PropertyValue
100 N2aa71a2ca7e649ee9eca55301917b2c6 rdf:first Nbc5d2957560643348f13d07c4d61ac1d
101 rdf:rest rdf:nil
102 N568535a8291d4bbf81e0ea060248957a schema:name readcube_id
103 schema:value ffade6fe85c620b622f7f7e2f0256d376eba1174276e4fcc72c65f3bae104d11
104 rdf:type schema:PropertyValue
105 N5fa4ecfdb03345239154c818d38697e2 rdf:first sg:person.01002303570.20
106 rdf:rest rdf:nil
107 N8138b1d66e534aa887659b0566844f90 schema:name dimensions_id
108 schema:value pub.1053678757
109 rdf:type schema:PropertyValue
110 Nbc5d2957560643348f13d07c4d61ac1d schema:familyName Lajtha
111 schema:givenName Abel
112 rdf:type schema:Person
113 Nc566d39bbe7e4aac81c0c63d2413cf40 schema:isbn 978-1-4757-6740-7
114 978-1-4757-6742-1
115 schema:name Alterations of Metabolites in the Nervous System
116 rdf:type schema:Book
117 Nd8aa93b35380410c90412ce7523572d4 schema:location Boston, MA
118 schema:name Springer US
119 rdf:type schema:Organisation
120 Ndc80881a503a4f7da49fba5301987ed3 schema:name Springer Nature - SN SciGraph project
121 rdf:type schema:Organization
122 anzsrc-for:17 schema:inDefinedTermSet anzsrc-for:
123 schema:name Psychology and Cognitive Sciences
124 rdf:type schema:DefinedTerm
125 anzsrc-for:1701 schema:inDefinedTermSet anzsrc-for:
126 schema:name Psychology
127 rdf:type schema:DefinedTerm
128 sg:person.01002303570.20 schema:affiliation https://www.grid.ac/institutes/grid.250263.0
129 schema:familyName Sershen
130 schema:givenName Henry
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01002303570.20
132 rdf:type schema:Person
133 sg:pub.10.1007/bf00426913 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030020688
134 https://doi.org/10.1007/bf00426913
135 rdf:type schema:CreativeWork
136 sg:pub.10.1007/bf00492216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050314386
137 https://doi.org/10.1007/bf00492216
138 rdf:type schema:CreativeWork
139 sg:pub.10.1007/bf00496056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034135312
140 https://doi.org/10.1007/bf00496056
141 rdf:type schema:CreativeWork
142 sg:pub.10.1007/bf00965094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028677720
143 https://doi.org/10.1007/bf00965094
144 rdf:type schema:CreativeWork
145 sg:pub.10.1007/bf01247320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003761983
146 https://doi.org/10.1007/bf01247320
147 rdf:type schema:CreativeWork
148 sg:pub.10.1007/bf01926479 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010835587
149 https://doi.org/10.1007/bf01926479
150 rdf:type schema:CreativeWork
151 sg:pub.10.1038/2111415a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001497567
152 https://doi.org/10.1038/2111415a0
153 rdf:type schema:CreativeWork
154 sg:pub.10.1038/217331a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002570855
155 https://doi.org/10.1038/217331a0
156 rdf:type schema:CreativeWork
157 sg:pub.10.1038/243199a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013236328
158 https://doi.org/10.1038/243199a0
159 rdf:type schema:CreativeWork
160 sg:pub.10.1038/283489a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051670505
161 https://doi.org/10.1038/283489a0
162 rdf:type schema:CreativeWork
163 https://app.dimensions.ai/details/publication/pub.1075098439 schema:CreativeWork
164 https://app.dimensions.ai/details/publication/pub.1076106240 schema:CreativeWork
165 https://app.dimensions.ai/details/publication/pub.1078103840 schema:CreativeWork
166 https://app.dimensions.ai/details/publication/pub.1078564391 schema:CreativeWork
167 https://app.dimensions.ai/details/publication/pub.1080638874 schema:CreativeWork
168 https://app.dimensions.ai/details/publication/pub.1080697516 schema:CreativeWork
169 https://app.dimensions.ai/details/publication/pub.1081079420 schema:CreativeWork
170 https://app.dimensions.ai/details/publication/pub.1081108817 schema:CreativeWork
171 https://app.dimensions.ai/details/publication/pub.1081594341 schema:CreativeWork
172 https://app.dimensions.ai/details/publication/pub.1081871460 schema:CreativeWork
173 https://app.dimensions.ai/details/publication/pub.1082005841 schema:CreativeWork
174 https://app.dimensions.ai/details/publication/pub.1082012095 schema:CreativeWork
175 https://app.dimensions.ai/details/publication/pub.1082158781 schema:CreativeWork
176 https://app.dimensions.ai/details/publication/pub.1082161896 schema:CreativeWork
177 https://app.dimensions.ai/details/publication/pub.1082181927 schema:CreativeWork
178 https://doi.org/10.1002/jnr.490030503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019002974
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1002/jnr.490040202 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008107466
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1016/0006-2952(70)90135-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041209884
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1016/0006-2952(72)90179-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023261994
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1016/0006-2952(73)90196-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034157975
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1016/0006-2952(77)90080-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033571198
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1016/0006-2952(78)90040-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049878984
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1016/0006-8993(73)90035-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022503637
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1016/0006-8993(76)90558-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013757261
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1016/0006-8993(79)90578-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001115521
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1016/0006-8993(82)91290-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018418182
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/0014-2999(73)90240-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020835738
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/0024-3205(79)90469-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006220773
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/0024-3205(80)90224-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043108792
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/0028-3908(72)90048-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003822096
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0028-3908(74)90007-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009315732
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/0028-3908(74)90015-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1012299764
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/0028-3908(81)90176-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053174139
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/0028-3908(82)90107-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018199941
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/0160-5402(83)90064-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003483380
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/0163-7258(82)90058-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003377054
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/s0021-9673(01)80452-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002570294
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/s0196-9781(81)80005-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043550996
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1021/jm00182a028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055938039
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1042/bj1150889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010624113
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1073/pnas.71.5.1852 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023004737
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1073/pnas.79.4.1321 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030257071
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1073/pnas.80.11.3536 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008848806
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1111/j.1471-4159.1982.tb08669.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019074141
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1111/j.1471-4159.1983.tb00824.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025642519
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1111/j.1476-5381.1971.tb08050.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022726487
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1111/j.2042-7158.1957.tb12289.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040131045
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1111/j.2042-7158.1965.tb07717.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042543140
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1111/j.2042-7158.1979.tb13435.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001677732
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1126/science.163.3863.139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062496092
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1126/science.619461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062635065
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1126/science.7291998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062645253
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1126/science.7433991 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062646719
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1159/000117935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033171753
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1159/000117954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034928475
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1159/000117969 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049323231
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1159/000241188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014460073
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1161/01.str.10.5.577 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002498242
263 rdf:type schema:CreativeWork
264 https://doi.org/10.3109/03602537808993776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008783024
265 rdf:type schema:CreativeWork
266 https://doi.org/10.3181/00379727-147-38444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050265482
267 rdf:type schema:CreativeWork
268 https://www.grid.ac/institutes/grid.250263.0 schema:alternateName Nathan Kline Institute for Psychiatric Research
269 schema:name Center for Neurochemistry, The Nathan S. Kline Institute for Psychiatric Research, Wards Island, New York 10035, USA
270 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...