The Photoimmunology of Delayed-Type Hypersensitivity and Its Relationship to Photocarcinogenesis View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1983

AUTHORS

Edward C. De Fabo , Frances P. Noonan

ABSTRACT

The association between skin cancer and ultraviolet radiation has been known for a long time. In 1934, it was demonstrated that by filtering sunlight with ordinary window glass and then exposing white rats to this light the carcinogenic activity associated with unfiltered sunlight was eliminated.1 This suggested that the carcinogenic wavelengths had to be between 290 nm, the approximate lower wavelength limit of sunlight penetration through the atmosphere2 and 320 nm radiation, the approximate lower wavelength limit of penetration through window glass. This waveband is commonly defined as UVB. Since that time a large amount of circumstantial data supporting the role of sunlight (UVB) in at least three types of human skin cancer has accrued.2 These three types are basal cell epitheliomas, squanous cell carcinomas and melanoma. More... »

PAGES

95-106

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4757-0896-7_7

DOI

http://dx.doi.org/10.1007/978-1-4757-0896-7_7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014626890


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