Atypical Presentations View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1989

AUTHORS

Ciro Valent Sumaya

ABSTRACT

Defined criteria to establish the diagnosis of infectious mononucleosis (IM) are essential before atypical presentations of this disease can be appreciated. Hoagland (1952) believed that a valid diagnosis of IM must fulfill three criteria: characteristic clinical manifestations, hematologic manifestations, and serology. The clinical findings should include a constellation of such signs as fever, cervical adenitis, pharyngeal inflammation, and, to a lesser extent, hepatomegaly and other signs. Minimal hematologic features are a relative lymphocytosis greater than 50 percent of all leukocytes and the presence of atypical lymphocytes for at least 10 days. Bender (1952) felt that atypical lymphocytes in the peripheral blood in IM should have an absolute concentration of at least 1,000/mm3 (many investigators currently use 10 percent of the leukocyte population as a minimal criterion). Hoagland (1952) also believed that a true case of IM must exhibit an appropriate serologic response, namely, the development of characteristic heterophile antibodies. The typical cases of IM have been described traditionally in young adult patients. More... »

PAGES

69-79

References to SciGraph publications

  • 1983-04. Changes in T-lymphocyte subsets during childhood Epstein-Barr virus infectious mononucleosis in JOURNAL OF CLINICAL IMMUNOLOGY
  • 1972-08. Acute Epstein-Barr virus infections in children in MEDICAL MICROBIOLOGY AND IMMUNOLOGY
  • Book

    TITLE

    Infectious Mononucleosis

    ISBN

    978-1-4684-6378-1
    978-1-4684-6376-7

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-1-4684-6376-7_6

    DOI

    http://dx.doi.org/10.1007/978-1-4684-6376-7_6

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1023363824


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