Expression and Characterization of Genetically Linked Homo- and Hetero-Dimers of Hiv Proteinase View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

Hans-Georg Kräusslich , Anke-Mareil Traenckner , Friedrich Rippmann

ABSTRACT

Infectious retroviral particles are composed of an inner core structure enclosed in a host-derived plasma membrane that contains the viral glycoproteins. In the case of HIV, this inner core consists of a ribonucleoprotein complex (two identical molecules of genomic RNA associated with the viral nucleocapsid [NC] protein and probably also with the viral enzymes reverse transcriptase [RT], integrase [IN] and proteinase [PR]) encased in a capsid [CA] shell (Gelderblom et al., 1989). All structural components of the viral core (derived from the viral gag gene) as well as the replication enzymes (derived from the pol gene) are synthesized and assembled as polyprotein precursors. Proteolytic processing by the virus-encoded, virion-associated proteinase takes place only during and after budding of the viral particle from the plasma membrane and processing is not required for the release of immature, non-infectious particles but is necessary for maturation of infectious virions (reviewed in Kräusslich & Wimmer, 1988). This elaborate mechanism of synthesizing different stable polyproteins at defined rates enables the virus to target many components of the viral particle to the site of assembly using only a single targeting signal. It requires, however, that a proteolytic enzyme is packaged into the virion that is capable of separating the different functional domains, thus allowing viral replication to occur. The activity of such an enzyme has to be tightly regulated since premature processing would dissociate the components of the virion from the site of assembly and incomplete or unfaithful processing should interfere with viral uncoating and replication. Controlled limited proteolysis can be achieved by synthesizing an inactive form of the viral proteinase as part of the polyprotein which is activated upon assembly of the viral particle. More... »

PAGES

417-28

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4684-6012-4_54

DOI

http://dx.doi.org/10.1007/978-1-4684-6012-4_54

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043470034

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1812738


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1108", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical Microbiology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Binding Sites", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Escherichia coli", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Expression", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Vectors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "HIV Protease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Hydrogen Bonding", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutagenesis, Site-Directed", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "German Cancer Research Center", 
          "id": "https://www.grid.ac/institutes/grid.7497.d", 
          "name": [
            "Institut f\u00fcr Virusforschung/ATV, Deutsches Krebsforschungszentrum, D-6900\u00a0Heidelberg, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kr\u00e4usslich", 
        "givenName": "Hans-Georg", 
        "id": "sg:person.0731120455.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731120455.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "German Cancer Research Center", 
          "id": "https://www.grid.ac/institutes/grid.7497.d", 
          "name": [
            "Institut f\u00fcr Virusforschung/ATV, Deutsches Krebsforschungszentrum, D-6900\u00a0Heidelberg, Deutschland"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Traenckner", 
        "givenName": "Anke-Mareil", 
        "id": "sg:person.01014660432.88", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014660432.88"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Mathematical Biology, The National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Rippmann", 
        "givenName": "Friedrich", 
        "id": "sg:person.0670426330.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670426330.15"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.86.3.807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000854447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/340397a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001813340", 
          "https://doi.org/10.1038/340397a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/315691a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015610661", 
          "https://doi.org/10.1038/315691a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(90)90015-t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017455388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(90)90015-t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017455388"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01311033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022451123", 
          "https://doi.org/10.1007/bf01311033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf01311033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022451123", 
          "https://doi.org/10.1007/bf01311033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.82.2.488", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026991187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(87)90165-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033703436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(87)90165-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033703436"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/313277a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034786339", 
          "https://doi.org/10.1038/313277a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(88)90199-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039129495"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bi.57.070188.003413", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046230258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.14.5573", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050069183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(87)90563-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051256034"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00452a001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055176814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00477a002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055177678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.2548279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062543225"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1079525386", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1991", 
    "datePublishedReg": "1991-01-01", 
    "description": "Infectious retroviral particles are composed of an inner core structure enclosed in a host-derived plasma membrane that contains the viral glycoproteins. In the case of HIV, this inner core consists of a ribonucleoprotein complex (two identical molecules of genomic RNA associated with the viral nucleocapsid [NC] protein and probably also with the viral enzymes reverse transcriptase [RT], integrase [IN] and proteinase [PR]) encased in a capsid [CA] shell (Gelderblom et al., 1989). All structural components of the viral core (derived from the viral gag gene) as well as the replication enzymes (derived from the pol gene) are synthesized and assembled as polyprotein precursors. Proteolytic processing by the virus-encoded, virion-associated proteinase takes place only during and after budding of the viral particle from the plasma membrane and processing is not required for the release of immature, non-infectious particles but is necessary for maturation of infectious virions (reviewed in Kr\u00e4usslich & Wimmer, 1988). This elaborate mechanism of synthesizing different stable polyproteins at defined rates enables the virus to target many components of the viral particle to the site of assembly using only a single targeting signal. It requires, however, that a proteolytic enzyme is packaged into the virion that is capable of separating the different functional domains, thus allowing viral replication to occur. The activity of such an enzyme has to be tightly regulated since premature processing would dissociate the components of the virion from the site of assembly and incomplete or unfaithful processing should interfere with viral uncoating and replication. Controlled limited proteolysis can be achieved by synthesizing an inactive form of the viral proteinase as part of the polyprotein which is activated upon assembly of the viral particle.", 
    "editor": [
      {
        "familyName": "Dunn", 
        "givenName": "Ben M.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4684-6012-4_54", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4684-6014-8", 
        "978-1-4684-6012-4"
      ], 
      "name": "Structure and Function of the Aspartic Proteinases", 
      "type": "Book"
    }, 
    "name": "Expression and Characterization of Genetically Linked Homo- and Hetero-Dimers of Hiv Proteinase", 
    "pagination": "417-28", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4684-6012-4_54"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "cf105982510faf9d44e31aa7b3ad5c817270fe2191d6514a179136003987aa56"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1043470034"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "1812738"
        ]
      }
    ], 
    "publisher": {
      "location": "Boston, MA", 
      "name": "Springer US", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4684-6012-4_54", 
      "https://app.dimensions.ai/details/publication/pub.1043470034"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T22:00", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8693_00000270.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4684-6012-4_54"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-6012-4_54'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-6012-4_54'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-6012-4_54'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-6012-4_54'


 

This table displays all metadata directly associated to this object as RDF triples.

181 TRIPLES      23 PREDICATES      55 URIs      32 LITERALS      20 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4684-6012-4_54 schema:about N038344b3226b400dad64cb3d4f5809fb
2 N62c1d5b3cf6c4ab3b00f498c2a7a32e6
3 N688c7449f1c946ddb756dad152001cec
4 N6c19c564379d4ad29b599588ad07faa3
5 N7b6d080ff923436c8290097ab02b2443
6 N82e337adb61c43c4aade3898a52e80ce
7 N8a3e657df2e94cc9b335d2cbad8b96bf
8 N8a6ec5f956e44c15ae4ae968f51e6e3a
9 Na1d33ff3d7e14cacbd43588a83b36ad7
10 Nb56bf73e7b664a7f893f847d6b0021c4
11 Nd34c2fc43881492e90103abaffa52fb5
12 anzsrc-for:11
13 anzsrc-for:1108
14 schema:author Nb3cb706d43fc47329157b4f8c8651f75
15 schema:citation sg:pub.10.1007/bf01311033
16 sg:pub.10.1038/313277a0
17 sg:pub.10.1038/315691a0
18 sg:pub.10.1038/340397a0
19 https://app.dimensions.ai/details/publication/pub.1079525386
20 https://doi.org/10.1016/0092-8674(87)90563-0
21 https://doi.org/10.1016/0092-8674(88)90199-7
22 https://doi.org/10.1016/0167-4781(90)90015-t
23 https://doi.org/10.1016/0378-1119(87)90165-x
24 https://doi.org/10.1021/bi00452a001
25 https://doi.org/10.1021/bi00477a002
26 https://doi.org/10.1073/pnas.82.2.488
27 https://doi.org/10.1073/pnas.86.3.807
28 https://doi.org/10.1073/pnas.87.14.5573
29 https://doi.org/10.1126/science.2548279
30 https://doi.org/10.1146/annurev.bi.57.070188.003413
31 schema:datePublished 1991
32 schema:datePublishedReg 1991-01-01
33 schema:description Infectious retroviral particles are composed of an inner core structure enclosed in a host-derived plasma membrane that contains the viral glycoproteins. In the case of HIV, this inner core consists of a ribonucleoprotein complex (two identical molecules of genomic RNA associated with the viral nucleocapsid [NC] protein and probably also with the viral enzymes reverse transcriptase [RT], integrase [IN] and proteinase [PR]) encased in a capsid [CA] shell (Gelderblom et al., 1989). All structural components of the viral core (derived from the viral gag gene) as well as the replication enzymes (derived from the pol gene) are synthesized and assembled as polyprotein precursors. Proteolytic processing by the virus-encoded, virion-associated proteinase takes place only during and after budding of the viral particle from the plasma membrane and processing is not required for the release of immature, non-infectious particles but is necessary for maturation of infectious virions (reviewed in Kräusslich & Wimmer, 1988). This elaborate mechanism of synthesizing different stable polyproteins at defined rates enables the virus to target many components of the viral particle to the site of assembly using only a single targeting signal. It requires, however, that a proteolytic enzyme is packaged into the virion that is capable of separating the different functional domains, thus allowing viral replication to occur. The activity of such an enzyme has to be tightly regulated since premature processing would dissociate the components of the virion from the site of assembly and incomplete or unfaithful processing should interfere with viral uncoating and replication. Controlled limited proteolysis can be achieved by synthesizing an inactive form of the viral proteinase as part of the polyprotein which is activated upon assembly of the viral particle.
34 schema:editor Nc04441b0746749458111e2c04372ca23
35 schema:genre chapter
36 schema:inLanguage en
37 schema:isAccessibleForFree false
38 schema:isPartOf N15e2f08193684e1ea14240baf5fc3ebb
39 schema:name Expression and Characterization of Genetically Linked Homo- and Hetero-Dimers of Hiv Proteinase
40 schema:pagination 417-28
41 schema:productId N0e0f743365614e809fb2fb6c61874bbe
42 N27496c6a206e4cc3b2524b9a0f80e628
43 Nce482fb898304a4d9ac782da30fbcc09
44 Nd8b9780969344b8abe1c5274f05fb909
45 schema:publisher Nb903032be8544651afad3ae2365bb8a2
46 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043470034
47 https://doi.org/10.1007/978-1-4684-6012-4_54
48 schema:sdDatePublished 2019-04-15T22:00
49 schema:sdLicense https://scigraph.springernature.com/explorer/license/
50 schema:sdPublisher Nabe25977887c44b5bfca4c05697ad913
51 schema:url http://link.springer.com/10.1007/978-1-4684-6012-4_54
52 sgo:license sg:explorer/license/
53 sgo:sdDataset chapters
54 rdf:type schema:Chapter
55 N038344b3226b400dad64cb3d4f5809fb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
56 schema:name Gene Expression
57 rdf:type schema:DefinedTerm
58 N0e0f743365614e809fb2fb6c61874bbe schema:name doi
59 schema:value 10.1007/978-1-4684-6012-4_54
60 rdf:type schema:PropertyValue
61 N15e2f08193684e1ea14240baf5fc3ebb schema:isbn 978-1-4684-6012-4
62 978-1-4684-6014-8
63 schema:name Structure and Function of the Aspartic Proteinases
64 rdf:type schema:Book
65 N27496c6a206e4cc3b2524b9a0f80e628 schema:name readcube_id
66 schema:value cf105982510faf9d44e31aa7b3ad5c817270fe2191d6514a179136003987aa56
67 rdf:type schema:PropertyValue
68 N3c8355425ecf4453af8c360ea010267b schema:familyName Dunn
69 schema:givenName Ben M.
70 rdf:type schema:Person
71 N62c1d5b3cf6c4ab3b00f498c2a7a32e6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
72 schema:name Escherichia coli
73 rdf:type schema:DefinedTerm
74 N688c7449f1c946ddb756dad152001cec schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
75 schema:name Genetic Vectors
76 rdf:type schema:DefinedTerm
77 N6c19c564379d4ad29b599588ad07faa3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Amino Acid Sequence
79 rdf:type schema:DefinedTerm
80 N7b6d080ff923436c8290097ab02b2443 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Protein Conformation
82 rdf:type schema:DefinedTerm
83 N804e8cf3b2d84043b583a9a3cedd6796 rdf:first sg:person.01014660432.88
84 rdf:rest N898ccc30e0f049b3a3bbc118410687d6
85 N82e337adb61c43c4aade3898a52e80ce schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
86 schema:name HIV Protease
87 rdf:type schema:DefinedTerm
88 N898ccc30e0f049b3a3bbc118410687d6 rdf:first sg:person.0670426330.15
89 rdf:rest rdf:nil
90 N8a3e657df2e94cc9b335d2cbad8b96bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Mutagenesis, Site-Directed
92 rdf:type schema:DefinedTerm
93 N8a6ec5f956e44c15ae4ae968f51e6e3a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
94 schema:name Models, Molecular
95 rdf:type schema:DefinedTerm
96 Na1d33ff3d7e14cacbd43588a83b36ad7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Binding Sites
98 rdf:type schema:DefinedTerm
99 Nabe25977887c44b5bfca4c05697ad913 schema:name Springer Nature - SN SciGraph project
100 rdf:type schema:Organization
101 Nb3cb706d43fc47329157b4f8c8651f75 rdf:first sg:person.0731120455.54
102 rdf:rest N804e8cf3b2d84043b583a9a3cedd6796
103 Nb56bf73e7b664a7f893f847d6b0021c4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
104 schema:name Hydrogen Bonding
105 rdf:type schema:DefinedTerm
106 Nb903032be8544651afad3ae2365bb8a2 schema:location Boston, MA
107 schema:name Springer US
108 rdf:type schema:Organisation
109 Nc04441b0746749458111e2c04372ca23 rdf:first N3c8355425ecf4453af8c360ea010267b
110 rdf:rest rdf:nil
111 Nce482fb898304a4d9ac782da30fbcc09 schema:name pubmed_id
112 schema:value 1812738
113 rdf:type schema:PropertyValue
114 Nd34c2fc43881492e90103abaffa52fb5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
115 schema:name Molecular Sequence Data
116 rdf:type schema:DefinedTerm
117 Nd8b9780969344b8abe1c5274f05fb909 schema:name dimensions_id
118 schema:value pub.1043470034
119 rdf:type schema:PropertyValue
120 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
121 schema:name Medical and Health Sciences
122 rdf:type schema:DefinedTerm
123 anzsrc-for:1108 schema:inDefinedTermSet anzsrc-for:
124 schema:name Medical Microbiology
125 rdf:type schema:DefinedTerm
126 sg:person.01014660432.88 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
127 schema:familyName Traenckner
128 schema:givenName Anke-Mareil
129 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014660432.88
130 rdf:type schema:Person
131 sg:person.0670426330.15 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
132 schema:familyName Rippmann
133 schema:givenName Friedrich
134 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670426330.15
135 rdf:type schema:Person
136 sg:person.0731120455.54 schema:affiliation https://www.grid.ac/institutes/grid.7497.d
137 schema:familyName Kräusslich
138 schema:givenName Hans-Georg
139 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731120455.54
140 rdf:type schema:Person
141 sg:pub.10.1007/bf01311033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022451123
142 https://doi.org/10.1007/bf01311033
143 rdf:type schema:CreativeWork
144 sg:pub.10.1038/313277a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034786339
145 https://doi.org/10.1038/313277a0
146 rdf:type schema:CreativeWork
147 sg:pub.10.1038/315691a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015610661
148 https://doi.org/10.1038/315691a0
149 rdf:type schema:CreativeWork
150 sg:pub.10.1038/340397a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001813340
151 https://doi.org/10.1038/340397a0
152 rdf:type schema:CreativeWork
153 https://app.dimensions.ai/details/publication/pub.1079525386 schema:CreativeWork
154 https://doi.org/10.1016/0092-8674(87)90563-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051256034
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/0092-8674(88)90199-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039129495
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/0167-4781(90)90015-t schema:sameAs https://app.dimensions.ai/details/publication/pub.1017455388
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/0378-1119(87)90165-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033703436
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1021/bi00452a001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055176814
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1021/bi00477a002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055177678
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1073/pnas.82.2.488 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026991187
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1073/pnas.86.3.807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000854447
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1073/pnas.87.14.5573 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050069183
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1126/science.2548279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062543225
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1146/annurev.bi.57.070188.003413 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046230258
175 rdf:type schema:CreativeWork
176 https://www.grid.ac/institutes/grid.451388.3 schema:alternateName The Francis Crick Institute
177 schema:name Laboratory of Mathematical Biology, The National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, UK
178 rdf:type schema:Organization
179 https://www.grid.ac/institutes/grid.7497.d schema:alternateName German Cancer Research Center
180 schema:name Institut für Virusforschung/ATV, Deutsches Krebsforschungszentrum, D-6900 Heidelberg, Deutschland
181 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...