High Levels of Oncomodulin and Calmodulin Expression in the Log Phase of Cell Growth in a Chemically Transformed Rat Fibroblast ... View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1990

AUTHORS

Janaki K. Blum , Ernst W. Sommer , Marianne C. Berger , Martin W. Berchtold

ABSTRACT

A variety of cellular processes are under the regulatory control of calcium. Alterations in fluxes and steady state levels of intracellular calcium appear to be responsible for evoking these events. Calcium homeostasis has been reported to be altered during tumorigenesis as well as upon transformation of cells in vitro by chemicals or viruses1. Neither the underlying molecular mechanisms related to calcium regulation in normal and tumor cells, nor the fact that transformed cells do not respond properly to normal regulatory controls are as yet well understood. Increased intracellular calcium levels could be partially responsible for a permanent activation of DNA synthesis and/or an increased mobility (invasive behaviour) of tumor cells. More... »

PAGES

121-5

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4684-5754-4_19

DOI

http://dx.doi.org/10.1007/978-1-4684-5754-4_19

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1050415311

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/2191549


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