Antibodies Against Synthetic Peptides View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1983

AUTHORS

Gernot Walter , Russell F. Doolittle

ABSTRACT

The introduction of a simple and efficient peptide synthesis methodology in the early 1960’s (1) put a powerful research tool at the disposal of biologists and protein chemists alike. Thus, it was immediately feasible to synthesize not only biologically active peptides, but also discrete segments of proteins. It was obvious from the start, also, that this technology could be coupled with longstanding immunologic procedures whereby small molecules can be used as antigenic materials (2). Indeed, the approach was soon applied to a number of proteins in a quest to find what features made them antigenic (3). It is fair to say, though, that the full capacity of the combined immunologic and synthetic techniques was never exploited during the 1960’s and 1970’s. Since then advances in the field of DNA sequencing have provided a plethora of sequence information about proteins, real and putative, many of which have never been isolated, never mind characterized. The sequence data can be utilized in a variety of ways, especially in conjunction with computer-aided predictive schemes that allow a degree of meaningful conjecture about the three-dimensional structure of a given sequence. Among the ends to which DNA/protein sequence data can be put is the chemical synthesis of peptides corresponding to portions of the protein. More... »

PAGES

61-91

References to SciGraph publications

  • 1978-04. Prediction of chain turns in globular proteins on a hydrophobic basis in NATURE
  • 1982-07. Synthetic peptides as the basis for future vaccines in NATURE
  • 1979-05. Cloning and endonuclease mapping of the hepatitis B viral genome in NATURE
  • 1980-10. Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product in NATURE
  • 1978-05. Complete nucleotide sequence of SV40 DNA in NATURE
  • 1982-07. Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence in NATURE
  • 1977. Immunochemistry of Protein Mutants in IMMUNOCHEMISTRY OF PROTEINS
  • 1982-03. Molecular recognition and the future of monoclonal antibodies in NATURE
  • 1980-08. Precise determination of protein antigenic structures has unravelled the molecular immune recognition of proteins and provided a prototype for synthetic mimicking of other protein binding sites in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 1979. Antigenic Features of Immunoglobulins in IMMUNOCHEMISTRY OF PROTEINS
  • 1979. Immunochemistry of Bovine Serum Albumin in IMMUNOCHEMISTRY OF PROTEINS
  • 1981-07. Type-specific protective immunity evoked by synthetic peptide of Streptococcus pyogenes M protein in NATURE
  • 1979-12. Hepatitis B virus genes and their expression in E. coli in NATURE
  • 1981-01. Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation in NATURE
  • 1981-01. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution in NATURE
  • 1981-03. Hepatitis B polypeptide vaccine preparation in micelle form in NATURE
  • 1981-01. Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus in NATURE
  • 1982-03. Molecular mechanisms of variation in influenza viruses in NATURE
  • 1979-05. Expression in Escherichia coli of hepatitis B virus DNA sequences cloned in plasmid pBR322 in NATURE
  • 1979-08. Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen in NATURE
  • 1982-01. Antibody to hepatitis B surface antigen after a single inoculation of uncoupled synthetic HBsAg peptides in NATURE
  • 1981-02. Active antitoxic immunization by a diphtheria toxin synthetic oligopeptide in NATURE
  • 1982-01. Developing synthetic vaccines in NATURE
  • 1981-08. Cross-reactivity between Thy-1 and a component of intermediate filaments demonstrated using a monoclonal antibody in NATURE
  • Book

    TITLE

    Genetic Engineering

    ISBN

    978-1-4684-4558-9
    978-1-4684-4556-5

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-1-4684-4556-5_5

    DOI

    http://dx.doi.org/10.1007/978-1-4684-4556-5_5

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1019207220


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0305", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Organic Chemistry", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/03", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Chemical Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Freiburg", 
              "id": "https://www.grid.ac/institutes/grid.5963.9", 
              "name": [
                "Institut fur Immunbiologie, Albert-Ludwigs-Universitat, Stefan-Meier-Str.8, 7800\u00a0Freiburg i.Br., West Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Walter", 
            "givenName": "Gernot", 
            "id": "sg:person.013350022702.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013350022702.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, San Diego", 
              "id": "https://www.grid.ac/institutes/grid.266100.3", 
              "name": [
                "Department of Chemistry, University of California, San Diego, La Jolla, California\u00a092093, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Doolittle", 
            "givenName": "Russell F.", 
            "id": "sg:person.0725046016.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725046016.27"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/0378-1119(82)90068-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000277193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.5.2222", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000630212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-3495(67)86579-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000817489"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4613-2922-0_5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001390664", 
              "https://doi.org/10.1007/978-1-4613-2922-0_5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4613-2922-0_5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001390664", 
              "https://doi.org/10.1007/978-1-4613-2922-0_5"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-2836(82)90515-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001452096"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.240190203", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002997159"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-3002(63)91077-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005254375"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0006-3002(63)91077-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005254375"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/279043a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006254299", 
              "https://doi.org/10.1038/279043a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(81)90009-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006566873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(81)90009-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006566873"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/296115a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007332880", 
              "https://doi.org/10.1038/296115a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/279346a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008297302", 
              "https://doi.org/10.1038/279346a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/289593a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009701620", 
              "https://doi.org/10.1038/289593a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.9.4350", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011704795"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.77.9.5197", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012404064"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(82)90202-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012633798"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/295098a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012981216", 
              "https://doi.org/10.1038/295098a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/290051a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013030468", 
              "https://doi.org/10.1038/290051a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/290051a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013030468", 
              "https://doi.org/10.1038/290051a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/298014a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013043809", 
              "https://doi.org/10.1038/298014a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0065-3233(08)60608-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014054545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(81)90126-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014695736"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(82)90358-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014727964"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/289366a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016242659", 
              "https://doi.org/10.1038/289366a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(66)90067-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016429046"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(66)90067-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016429046"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.77.8.4643", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016704585"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.4.1059", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017209683"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/272586a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017230884", 
              "https://doi.org/10.1038/272586a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.77.9.5234", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018583179"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/287801a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018637284", 
              "https://doi.org/10.1038/287801a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/289258a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018787893", 
              "https://doi.org/10.1038/289258a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj1670275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019921323"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj1670275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019921323"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/273113a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020254632", 
              "https://doi.org/10.1038/273113a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.73.12.4636", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020823047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.8.4882", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020880381"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.mi.34.100180.003113", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023243584"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.6.3403", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023899900"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.2.569", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024579180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(81)90365-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027273407"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00421293", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028048662", 
              "https://doi.org/10.1007/bf00421293"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00421293", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028048662", 
              "https://doi.org/10.1007/bf00421293"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.13.4025", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028986626"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-2836(76)90004-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029655315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.12.7412", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030194065"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj1710429", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030242555"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1042/bj1710429", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030242555"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.14.4400", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030562181"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/8.12.2561", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031681215"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(65)90163-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031928907"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0304-4165(65)90163-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031928907"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/289373a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032880486", 
              "https://doi.org/10.1038/289373a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(78)90147-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032907768"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(78)90147-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032907768"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0042-6822(82)90028-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034029777"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4613-2922-0_2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035174333", 
              "https://doi.org/10.1007/978-1-4613-2922-0_2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4613-2922-0_2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035174333", 
              "https://doi.org/10.1007/978-1-4613-2922-0_2"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/282575a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035234743", 
              "https://doi.org/10.1038/282575a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.62.1.163", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035321806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.19.5939", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035757043"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/292457a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036496172", 
              "https://doi.org/10.1038/292457a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/9.8.1919", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037661667"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0065-2776(08)60207-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038376402"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.69.12.3790", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040225987"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/296200a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040409267", 
              "https://doi.org/10.1038/296200a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2795(71)90024-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040785548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0005-2795(71)90024-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040785548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(82)90357-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041219044"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0092-8674(82)90158-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042300501"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/295158a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042872425", 
              "https://doi.org/10.1038/295158a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-2836(73)90372-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042887427"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.17.5322", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043456796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/280815a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043641873", 
              "https://doi.org/10.1038/280815a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.68.7.1450", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045964206"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0019-2791(75)90010-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046625890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0019-2791(75)90010-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046625890"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/292772a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047281639", 
              "https://doi.org/10.1038/292772a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.6.3824", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047301083"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.79.2.579", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048701168"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0065-3527(08)60423-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048725854"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/298030a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049090502", 
              "https://doi.org/10.1038/298030a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0042-6822(82)90377-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049397811"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bi00786a005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055188445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja00897a025", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055755677"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1099/0022-1317-59-2-295", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060354668"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/sqb.1977.041.01.073", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060404664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.6264599", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062635940"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.6272395", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062635978"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.7302582", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062645823"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2105/ajph.43.11.1384", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068858527"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074654679", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081523110", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081604944", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081607674", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/j.1460-2075.1982.tb01262.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1081617042"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081664855", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1081664892", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1083093013", 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/978-1-4613-4193-2_6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1089828742", 
              "https://doi.org/10.1007/978-1-4613-4193-2_6"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "1983", 
        "datePublishedReg": "1983-01-01", 
        "description": "The introduction of a simple and efficient peptide synthesis methodology in the early 1960\u2019s (1) put a powerful research tool at the disposal of biologists and protein chemists alike. Thus, it was immediately feasible to synthesize not only biologically active peptides, but also discrete segments of proteins. It was obvious from the start, also, that this technology could be coupled with longstanding immunologic procedures whereby small molecules can be used as antigenic materials (2). Indeed, the approach was soon applied to a number of proteins in a quest to find what features made them antigenic (3). It is fair to say, though, that the full capacity of the combined immunologic and synthetic techniques was never exploited during the 1960\u2019s and 1970\u2019s. Since then advances in the field of DNA sequencing have provided a plethora of sequence information about proteins, real and putative, many of which have never been isolated, never mind characterized. The sequence data can be utilized in a variety of ways, especially in conjunction with computer-aided predictive schemes that allow a degree of meaningful conjecture about the three-dimensional structure of a given sequence. Among the ends to which DNA/protein sequence data can be put is the chemical synthesis of peptides corresponding to portions of the protein.", 
        "editor": [
          {
            "familyName": "Setlow", 
            "givenName": "Jane K.", 
            "type": "Person"
          }, 
          {
            "familyName": "Hollaender", 
            "givenName": "Alexander", 
            "type": "Person"
          }
        ], 
        "genre": "chapter", 
        "id": "sg:pub.10.1007/978-1-4684-4556-5_5", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": {
          "isbn": [
            "978-1-4684-4558-9", 
            "978-1-4684-4556-5"
          ], 
          "name": "Genetic Engineering", 
          "type": "Book"
        }, 
        "name": "Antibodies Against Synthetic Peptides", 
        "pagination": "61-91", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/978-1-4684-4556-5_5"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "5b841b4f3c0bdd672f3abb5f03e3eed743508ddb74d897f2f56da5772ef3d921"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1019207220"
            ]
          }
        ], 
        "publisher": {
          "location": "Boston, MA", 
          "name": "Springer US", 
          "type": "Organisation"
        }, 
        "sameAs": [
          "https://doi.org/10.1007/978-1-4684-4556-5_5", 
          "https://app.dimensions.ai/details/publication/pub.1019207220"
        ], 
        "sdDataset": "chapters", 
        "sdDatePublished": "2019-04-15T23:51", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000255.jsonl", 
        "type": "Chapter", 
        "url": "http://link.springer.com/10.1007/978-1-4684-4556-5_5"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-4556-5_5'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-4556-5_5'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-4556-5_5'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4684-4556-5_5'


     

    This table displays all metadata directly associated to this object as RDF triples.

    364 TRIPLES      23 PREDICATES      116 URIs      20 LITERALS      8 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/978-1-4684-4556-5_5 schema:about anzsrc-for:03
    2 anzsrc-for:0305
    3 schema:author N7d8d07bed4e147409225447b051d7c18
    4 schema:citation sg:pub.10.1007/978-1-4613-2922-0_2
    5 sg:pub.10.1007/978-1-4613-2922-0_5
    6 sg:pub.10.1007/978-1-4613-4193-2_6
    7 sg:pub.10.1007/bf00421293
    8 sg:pub.10.1038/272586a0
    9 sg:pub.10.1038/273113a0
    10 sg:pub.10.1038/279043a0
    11 sg:pub.10.1038/279346a0
    12 sg:pub.10.1038/280815a0
    13 sg:pub.10.1038/282575a0
    14 sg:pub.10.1038/287801a0
    15 sg:pub.10.1038/289258a0
    16 sg:pub.10.1038/289366a0
    17 sg:pub.10.1038/289373a0
    18 sg:pub.10.1038/289593a0
    19 sg:pub.10.1038/290051a0
    20 sg:pub.10.1038/292457a0
    21 sg:pub.10.1038/292772a0
    22 sg:pub.10.1038/295098a0
    23 sg:pub.10.1038/295158a0
    24 sg:pub.10.1038/296115a0
    25 sg:pub.10.1038/296200a0
    26 sg:pub.10.1038/298014a0
    27 sg:pub.10.1038/298030a0
    28 https://app.dimensions.ai/details/publication/pub.1074654679
    29 https://app.dimensions.ai/details/publication/pub.1081523110
    30 https://app.dimensions.ai/details/publication/pub.1081604944
    31 https://app.dimensions.ai/details/publication/pub.1081607674
    32 https://app.dimensions.ai/details/publication/pub.1081664855
    33 https://app.dimensions.ai/details/publication/pub.1081664892
    34 https://app.dimensions.ai/details/publication/pub.1083093013
    35 https://doi.org/10.1002/j.1460-2075.1982.tb01262.x
    36 https://doi.org/10.1002/jcb.240190203
    37 https://doi.org/10.1016/0005-2795(71)90024-9
    38 https://doi.org/10.1016/0006-3002(63)91077-1
    39 https://doi.org/10.1016/0019-2791(75)90010-5
    40 https://doi.org/10.1016/0022-2836(73)90372-0
    41 https://doi.org/10.1016/0022-2836(76)90004-8
    42 https://doi.org/10.1016/0022-2836(82)90515-0
    43 https://doi.org/10.1016/0042-6822(82)90028-9
    44 https://doi.org/10.1016/0042-6822(82)90377-4
    45 https://doi.org/10.1016/0092-8674(81)90126-4
    46 https://doi.org/10.1016/0092-8674(81)90365-2
    47 https://doi.org/10.1016/0092-8674(82)90158-1
    48 https://doi.org/10.1016/0092-8674(82)90202-1
    49 https://doi.org/10.1016/0092-8674(82)90357-9
    50 https://doi.org/10.1016/0092-8674(82)90358-0
    51 https://doi.org/10.1016/0161-5890(78)90147-5
    52 https://doi.org/10.1016/0161-5890(81)90009-2
    53 https://doi.org/10.1016/0304-4165(65)90163-7
    54 https://doi.org/10.1016/0304-4165(66)90067-5
    55 https://doi.org/10.1016/0378-1119(82)90068-3
    56 https://doi.org/10.1016/s0006-3495(67)86579-2
    57 https://doi.org/10.1016/s0065-2776(08)60207-2
    58 https://doi.org/10.1016/s0065-3233(08)60608-7
    59 https://doi.org/10.1016/s0065-3527(08)60423-6
    60 https://doi.org/10.1021/bi00786a005
    61 https://doi.org/10.1021/ja00897a025
    62 https://doi.org/10.1042/bj1670275
    63 https://doi.org/10.1042/bj1710429
    64 https://doi.org/10.1073/pnas.62.1.163
    65 https://doi.org/10.1073/pnas.68.7.1450
    66 https://doi.org/10.1073/pnas.69.12.3790
    67 https://doi.org/10.1073/pnas.73.12.4636
    68 https://doi.org/10.1073/pnas.76.5.2222
    69 https://doi.org/10.1073/pnas.76.9.4350
    70 https://doi.org/10.1073/pnas.77.8.4643
    71 https://doi.org/10.1073/pnas.77.9.5197
    72 https://doi.org/10.1073/pnas.77.9.5234
    73 https://doi.org/10.1073/pnas.78.12.7412
    74 https://doi.org/10.1073/pnas.78.6.3403
    75 https://doi.org/10.1073/pnas.78.6.3824
    76 https://doi.org/10.1073/pnas.78.8.4882
    77 https://doi.org/10.1073/pnas.79.13.4025
    78 https://doi.org/10.1073/pnas.79.14.4400
    79 https://doi.org/10.1073/pnas.79.17.5322
    80 https://doi.org/10.1073/pnas.79.19.5939
    81 https://doi.org/10.1073/pnas.79.2.569
    82 https://doi.org/10.1073/pnas.79.2.579
    83 https://doi.org/10.1073/pnas.79.4.1059
    84 https://doi.org/10.1093/nar/8.12.2561
    85 https://doi.org/10.1093/nar/9.8.1919
    86 https://doi.org/10.1099/0022-1317-59-2-295
    87 https://doi.org/10.1101/sqb.1977.041.01.073
    88 https://doi.org/10.1126/science.6264599
    89 https://doi.org/10.1126/science.6272395
    90 https://doi.org/10.1126/science.7302582
    91 https://doi.org/10.1146/annurev.mi.34.100180.003113
    92 https://doi.org/10.2105/ajph.43.11.1384
    93 schema:datePublished 1983
    94 schema:datePublishedReg 1983-01-01
    95 schema:description The introduction of a simple and efficient peptide synthesis methodology in the early 1960’s (1) put a powerful research tool at the disposal of biologists and protein chemists alike. Thus, it was immediately feasible to synthesize not only biologically active peptides, but also discrete segments of proteins. It was obvious from the start, also, that this technology could be coupled with longstanding immunologic procedures whereby small molecules can be used as antigenic materials (2). Indeed, the approach was soon applied to a number of proteins in a quest to find what features made them antigenic (3). It is fair to say, though, that the full capacity of the combined immunologic and synthetic techniques was never exploited during the 1960’s and 1970’s. Since then advances in the field of DNA sequencing have provided a plethora of sequence information about proteins, real and putative, many of which have never been isolated, never mind characterized. The sequence data can be utilized in a variety of ways, especially in conjunction with computer-aided predictive schemes that allow a degree of meaningful conjecture about the three-dimensional structure of a given sequence. Among the ends to which DNA/protein sequence data can be put is the chemical synthesis of peptides corresponding to portions of the protein.
    96 schema:editor N3e1d131759f044f68608cb407abbb746
    97 schema:genre chapter
    98 schema:inLanguage en
    99 schema:isAccessibleForFree false
    100 schema:isPartOf Nf5990827972a42e293b1c96580661a3e
    101 schema:name Antibodies Against Synthetic Peptides
    102 schema:pagination 61-91
    103 schema:productId N35bc86bfce054c97b92a50db7e4cf001
    104 Nc7ebd5982ec74526b585669175e02979
    105 Nd9e0ecb6738e4c95a55da079cb55306b
    106 schema:publisher N0dc4cc3bcb0d44b5acb7afe51aa988b1
    107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019207220
    108 https://doi.org/10.1007/978-1-4684-4556-5_5
    109 schema:sdDatePublished 2019-04-15T23:51
    110 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    111 schema:sdPublisher N510f99cbc7d14ff9800b612919223958
    112 schema:url http://link.springer.com/10.1007/978-1-4684-4556-5_5
    113 sgo:license sg:explorer/license/
    114 sgo:sdDataset chapters
    115 rdf:type schema:Chapter
    116 N0dc4cc3bcb0d44b5acb7afe51aa988b1 schema:location Boston, MA
    117 schema:name Springer US
    118 rdf:type schema:Organisation
    119 N35bc86bfce054c97b92a50db7e4cf001 schema:name dimensions_id
    120 schema:value pub.1019207220
    121 rdf:type schema:PropertyValue
    122 N36dabd77f3554505acc30e2803f36355 schema:familyName Hollaender
    123 schema:givenName Alexander
    124 rdf:type schema:Person
    125 N3e1d131759f044f68608cb407abbb746 rdf:first N5aa73a55184a41da8c5e6160ee960293
    126 rdf:rest N6b314118769c48279fc012737b9b2d4e
    127 N510f99cbc7d14ff9800b612919223958 schema:name Springer Nature - SN SciGraph project
    128 rdf:type schema:Organization
    129 N5aa73a55184a41da8c5e6160ee960293 schema:familyName Setlow
    130 schema:givenName Jane K.
    131 rdf:type schema:Person
    132 N5ba3d39b328f4b228ca102779ce7d897 rdf:first sg:person.0725046016.27
    133 rdf:rest rdf:nil
    134 N6b314118769c48279fc012737b9b2d4e rdf:first N36dabd77f3554505acc30e2803f36355
    135 rdf:rest rdf:nil
    136 N7d8d07bed4e147409225447b051d7c18 rdf:first sg:person.013350022702.51
    137 rdf:rest N5ba3d39b328f4b228ca102779ce7d897
    138 Nc7ebd5982ec74526b585669175e02979 schema:name readcube_id
    139 schema:value 5b841b4f3c0bdd672f3abb5f03e3eed743508ddb74d897f2f56da5772ef3d921
    140 rdf:type schema:PropertyValue
    141 Nd9e0ecb6738e4c95a55da079cb55306b schema:name doi
    142 schema:value 10.1007/978-1-4684-4556-5_5
    143 rdf:type schema:PropertyValue
    144 Nf5990827972a42e293b1c96580661a3e schema:isbn 978-1-4684-4556-5
    145 978-1-4684-4558-9
    146 schema:name Genetic Engineering
    147 rdf:type schema:Book
    148 anzsrc-for:03 schema:inDefinedTermSet anzsrc-for:
    149 schema:name Chemical Sciences
    150 rdf:type schema:DefinedTerm
    151 anzsrc-for:0305 schema:inDefinedTermSet anzsrc-for:
    152 schema:name Organic Chemistry
    153 rdf:type schema:DefinedTerm
    154 sg:person.013350022702.51 schema:affiliation https://www.grid.ac/institutes/grid.5963.9
    155 schema:familyName Walter
    156 schema:givenName Gernot
    157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013350022702.51
    158 rdf:type schema:Person
    159 sg:person.0725046016.27 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
    160 schema:familyName Doolittle
    161 schema:givenName Russell F.
    162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725046016.27
    163 rdf:type schema:Person
    164 sg:pub.10.1007/978-1-4613-2922-0_2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035174333
    165 https://doi.org/10.1007/978-1-4613-2922-0_2
    166 rdf:type schema:CreativeWork
    167 sg:pub.10.1007/978-1-4613-2922-0_5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001390664
    168 https://doi.org/10.1007/978-1-4613-2922-0_5
    169 rdf:type schema:CreativeWork
    170 sg:pub.10.1007/978-1-4613-4193-2_6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1089828742
    171 https://doi.org/10.1007/978-1-4613-4193-2_6
    172 rdf:type schema:CreativeWork
    173 sg:pub.10.1007/bf00421293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028048662
    174 https://doi.org/10.1007/bf00421293
    175 rdf:type schema:CreativeWork
    176 sg:pub.10.1038/272586a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017230884
    177 https://doi.org/10.1038/272586a0
    178 rdf:type schema:CreativeWork
    179 sg:pub.10.1038/273113a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020254632
    180 https://doi.org/10.1038/273113a0
    181 rdf:type schema:CreativeWork
    182 sg:pub.10.1038/279043a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006254299
    183 https://doi.org/10.1038/279043a0
    184 rdf:type schema:CreativeWork
    185 sg:pub.10.1038/279346a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008297302
    186 https://doi.org/10.1038/279346a0
    187 rdf:type schema:CreativeWork
    188 sg:pub.10.1038/280815a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043641873
    189 https://doi.org/10.1038/280815a0
    190 rdf:type schema:CreativeWork
    191 sg:pub.10.1038/282575a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035234743
    192 https://doi.org/10.1038/282575a0
    193 rdf:type schema:CreativeWork
    194 sg:pub.10.1038/287801a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018637284
    195 https://doi.org/10.1038/287801a0
    196 rdf:type schema:CreativeWork
    197 sg:pub.10.1038/289258a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018787893
    198 https://doi.org/10.1038/289258a0
    199 rdf:type schema:CreativeWork
    200 sg:pub.10.1038/289366a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016242659
    201 https://doi.org/10.1038/289366a0
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1038/289373a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032880486
    204 https://doi.org/10.1038/289373a0
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1038/289593a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009701620
    207 https://doi.org/10.1038/289593a0
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1038/290051a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013030468
    210 https://doi.org/10.1038/290051a0
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/292457a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036496172
    213 https://doi.org/10.1038/292457a0
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1038/292772a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047281639
    216 https://doi.org/10.1038/292772a0
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1038/295098a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012981216
    219 https://doi.org/10.1038/295098a0
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1038/295158a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042872425
    222 https://doi.org/10.1038/295158a0
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1038/296115a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007332880
    225 https://doi.org/10.1038/296115a0
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1038/296200a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040409267
    228 https://doi.org/10.1038/296200a0
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.1038/298014a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013043809
    231 https://doi.org/10.1038/298014a0
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1038/298030a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049090502
    234 https://doi.org/10.1038/298030a0
    235 rdf:type schema:CreativeWork
    236 https://app.dimensions.ai/details/publication/pub.1074654679 schema:CreativeWork
    237 https://app.dimensions.ai/details/publication/pub.1081523110 schema:CreativeWork
    238 https://app.dimensions.ai/details/publication/pub.1081604944 schema:CreativeWork
    239 https://app.dimensions.ai/details/publication/pub.1081607674 schema:CreativeWork
    240 https://app.dimensions.ai/details/publication/pub.1081664855 schema:CreativeWork
    241 https://app.dimensions.ai/details/publication/pub.1081664892 schema:CreativeWork
    242 https://app.dimensions.ai/details/publication/pub.1083093013 schema:CreativeWork
    243 https://doi.org/10.1002/j.1460-2075.1982.tb01262.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1081617042
    244 rdf:type schema:CreativeWork
    245 https://doi.org/10.1002/jcb.240190203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002997159
    246 rdf:type schema:CreativeWork
    247 https://doi.org/10.1016/0005-2795(71)90024-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040785548
    248 rdf:type schema:CreativeWork
    249 https://doi.org/10.1016/0006-3002(63)91077-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005254375
    250 rdf:type schema:CreativeWork
    251 https://doi.org/10.1016/0019-2791(75)90010-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046625890
    252 rdf:type schema:CreativeWork
    253 https://doi.org/10.1016/0022-2836(73)90372-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042887427
    254 rdf:type schema:CreativeWork
    255 https://doi.org/10.1016/0022-2836(76)90004-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029655315
    256 rdf:type schema:CreativeWork
    257 https://doi.org/10.1016/0022-2836(82)90515-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001452096
    258 rdf:type schema:CreativeWork
    259 https://doi.org/10.1016/0042-6822(82)90028-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034029777
    260 rdf:type schema:CreativeWork
    261 https://doi.org/10.1016/0042-6822(82)90377-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049397811
    262 rdf:type schema:CreativeWork
    263 https://doi.org/10.1016/0092-8674(81)90126-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014695736
    264 rdf:type schema:CreativeWork
    265 https://doi.org/10.1016/0092-8674(81)90365-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027273407
    266 rdf:type schema:CreativeWork
    267 https://doi.org/10.1016/0092-8674(82)90158-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042300501
    268 rdf:type schema:CreativeWork
    269 https://doi.org/10.1016/0092-8674(82)90202-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012633798
    270 rdf:type schema:CreativeWork
    271 https://doi.org/10.1016/0092-8674(82)90357-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041219044
    272 rdf:type schema:CreativeWork
    273 https://doi.org/10.1016/0092-8674(82)90358-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014727964
    274 rdf:type schema:CreativeWork
    275 https://doi.org/10.1016/0161-5890(78)90147-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032907768
    276 rdf:type schema:CreativeWork
    277 https://doi.org/10.1016/0161-5890(81)90009-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006566873
    278 rdf:type schema:CreativeWork
    279 https://doi.org/10.1016/0304-4165(65)90163-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031928907
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1016/0304-4165(66)90067-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016429046
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1016/0378-1119(82)90068-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000277193
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1016/s0006-3495(67)86579-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000817489
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1016/s0065-2776(08)60207-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038376402
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1016/s0065-3233(08)60608-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014054545
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1016/s0065-3527(08)60423-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048725854
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1021/bi00786a005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055188445
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1021/ja00897a025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055755677
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1042/bj1670275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019921323
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1042/bj1710429 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030242555
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1073/pnas.62.1.163 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035321806
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1073/pnas.68.7.1450 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045964206
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1073/pnas.69.12.3790 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040225987
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1073/pnas.73.12.4636 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020823047
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1073/pnas.76.5.2222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000630212
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1073/pnas.76.9.4350 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011704795
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1073/pnas.77.8.4643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016704585
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1073/pnas.77.9.5197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012404064
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1073/pnas.77.9.5234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018583179
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1073/pnas.78.12.7412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030194065
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1073/pnas.78.6.3403 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023899900
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1073/pnas.78.6.3824 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047301083
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1073/pnas.78.8.4882 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020880381
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1073/pnas.79.13.4025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028986626
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1073/pnas.79.14.4400 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030562181
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1073/pnas.79.17.5322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043456796
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1073/pnas.79.19.5939 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035757043
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1073/pnas.79.2.569 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024579180
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1073/pnas.79.2.579 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048701168
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1073/pnas.79.4.1059 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017209683
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1093/nar/8.12.2561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031681215
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1093/nar/9.8.1919 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037661667
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1099/0022-1317-59-2-295 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060354668
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1101/sqb.1977.041.01.073 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060404664
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1126/science.6264599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062635940
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1126/science.6272395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062635978
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1126/science.7302582 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062645823
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1146/annurev.mi.34.100180.003113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023243584
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.2105/ajph.43.11.1384 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068858527
    358 rdf:type schema:CreativeWork
    359 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
    360 schema:name Department of Chemistry, University of California, San Diego, La Jolla, California 92093, USA
    361 rdf:type schema:Organization
    362 https://www.grid.ac/institutes/grid.5963.9 schema:alternateName University of Freiburg
    363 schema:name Institut fur Immunbiologie, Albert-Ludwigs-Universitat, Stefan-Meier-Str.8, 7800 Freiburg i.Br., West Germany
    364 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...