Regulation of Brain Development View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1981

AUTHORS

N. Herschkowitz

ABSTRACT

The normal functioning of the complex brain structures depends, among a multitude of other factors, on integrated and synchronised metabolic pathways. The brain structures are formed according to a genetic blueprint, according to which enzymatic activities are turned on at determined times and, if substrates are available, complex and specific products can be formed — such as proteins, lipids and polysaccarides. In a second step these complex molecules are incorporated into brain structures. When the enzymatic activity is turned off, the synthesis of complex molecules decreases and the formation of structures is, therefore, slowed down (Fig. 1). An example is the formation of myelin which in the mouse depends on the supply of the lipid sulfatide. Cerebroside sulfotransferase (CST) is a key enzyme in sulfatide synthesis. More... »

PAGES

183-195

Book

TITLE

Investigation of Brain Function

ISBN

978-1-4684-4045-4
978-1-4684-4043-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4684-4043-0_11

DOI

http://dx.doi.org/10.1007/978-1-4684-4043-0_11

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1026069571


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