Prostacyclin View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1981

AUTHORS

S. Moncada , J. R. Vane

ABSTRACT

In 1976, the Wellcome group discovered that prostaglandin endoperoxides were transformed by a microsomal enzyme from blood vessels into an unstable substance which is a potent vasodilator and an inhibitor of platelet aggregation (13,14, 75,76, 42). This compound originally called PGX was later chemically identified as an intermediate in the formation of 6-oxo-PGFlα, a compound described earlier (95). PGX was then renamed prostacyclin and given the abbreviation of PGI2 (61). More... »

PAGES

203-221

Book

TITLE

The Prostaglandin System

ISBN

978-1-4684-3898-7
978-1-4684-3896-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4684-3896-3_16

DOI

http://dx.doi.org/10.1007/978-1-4684-3896-3_16

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1046464002


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