Glucocerebrosidase, a Membrane-Associated Lysosomal Enzyme Deficient in Gaucher Disease View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1987

AUTHORS

A. W. Schram , J. M. F. G. Aerts , S. van Weely , J. A. Barranger , J. M. Tager

ABSTRACT

Lysosomal storage diseases are characterized by a-massive intralysosomal accumulation of undegraded material, causing dysfunction of the cells involved [1]. The storage can have different causes, viz. (1)a generalized deficiency of one or more enzymes in the lysosomes, (2) deficiency of a cofactor required for the stability of one or more enzymes, or (3) deficiency of a cofactor required for expression of activity in vivo [2–5]. More... »

PAGES

113-126

References to SciGraph publications

Book

TITLE

Cells, Membranes, and Disease, Including Renal

ISBN

978-1-4684-1285-7
978-1-4684-1283-3

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4684-1283-3_11

DOI

http://dx.doi.org/10.1007/978-1-4684-1283-3_11

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017445297


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