Patch Clamp Detection of Neuroreceptor Modulators in Capillary Electrophoresis View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1997

AUTHORS

Kent Jardemark , Owe Orwar , Ingemar Jacobson , Alexander Moscho , Harvey A. Fishman , Anders Hamberger , Mats Sandberg , Richard H. Scheller , Richard N. Zare

ABSTRACT

Many areas of research in the life sciences have been hampered by the inability to analyse microenvironments for important biologically active species. For example, the identities of many fast acting neurotransmitter substances in the mammalian brain are unknown, even after at least thirty years of active research, and endogenous ligands to numerous orphan receptors (e.g., plasma membrane opiate receptors) already cloned, remain to be discovered. During the past twenty years, development in instrumentation for microanalysis has resulted in techniques capable of sample handling in the low femtoliter range (10–15 L). Yet the development of detection devices for bioactive compounds that are compatible with these instrumentations has been extremely slow. More... »

PAGES

1131-1138

References to SciGraph publications

Book

TITLE

Neurochemistry

ISBN

978-1-4613-7468-8
978-1-4615-5405-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-5405-9_190

DOI

http://dx.doi.org/10.1007/978-1-4615-5405-9_190

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1052147602


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