Neoadjuvant chemotherapy for nonmetastatic osteosarcoma of the extremities: The recent experience at the Rizzoli Institute View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1993

AUTHORS

G. Bacci , P. Picci , S. Ferrari , M. Avella , Brach A. del Prever , P. Ruggieri , R. Casadei , S. Lari , C. Monti , A. Cazzola , M. Campanacci

ABSTRACT

In the late 1970s Rosen et al. was the first to report the advantages of primary chemotherapy and delayed surgery (neoadjuvant chemotherapy) over adjuvant chemotherapy. The excellent results reported by these authors induced us to introduce neoadjuvant chemotherapy in 1983. In our first neoadjuvant study (OS/NEO/IOR-1°) preoperative chemotherapy consisted of two cycles of MTX and cisplatinum (CDP) (Figure 36-1). The rationale for the combined use of these two drugs has been described in a previous paper [1]. More... »

PAGES

299-308

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-3518-8_36

DOI

http://dx.doi.org/10.1007/978-1-4615-3518-8_36

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024169473

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/7682090


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