Fusogenic Properties of Uncleaved Spike Protein of Murine Coronavirus JHMV View Full Text


Ontology type: schema:Chapter      Open Access: True


Chapter Info

DATE

1994

AUTHORS

Fumihiro Taguchi , Toshio Ikeda , Keiichi Saeki , Hideyuki Kubo , Tateki Kikuchi

ABSTRACT

We have tested the fusogenic properties of cleaved and uncleaved spike (S) protein of mutine coronavirus (MCV) JHMV variant cl-2 by expressing the S protein by recombinant vaccinia viruses (RVVs). The amino acid sequence of the putative cleavage site of cl-2 S protein, Arg-Arg-Ala-Arg-Arg, was replaced by Arg-Thr-Ala-Leu-Glu by in vitro mutagenesis of cl-2 S gene. The RVVs having cl-2 S gene [RVV t(+)] or mutated cl-2 S gene [RVV t(-)] were tested for their ability to induce fusion as well as cleavability in DBT cells. After inoculation with RVV t(+) onto DBT cells, the fusion formation was first observed at 8 h postinoculation (p.i.) and spread throughout the whole culture by 24 h. In cells infected with RVV t(-), fusion appeared by 2 h and most of cells were fused by 30 h p.i. The S protein and its cleavage products were detected in DBT cells expressing wild type S protein. However, no cleavage products of the S protein were detected in RVV t(-) infected cells producing mutated S protein, even though fusion was clearly visible. These results suggest that the cleavage event of JHMV-S protein of MCV is not a prerequisite for fusion formation, but that it enhances fusion. More... »

PAGES

171-175

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-2996-5_27

DOI

http://dx.doi.org/10.1007/978-1-4615-2996-5_27

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1001030813

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8209726


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Amino Acid Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Astrocytoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cell Fusion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cytopathogenic Effect, Viral", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Endopeptidases", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Membrane Glycoproteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mice", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Murine hepatitis virus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutagenesis, Site-Directed", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Processing, Post-Translational", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spike Glycoprotein, Coronavirus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Viral Envelope Proteins", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Taguchi", 
        "givenName": "Fumihiro", 
        "id": "sg:person.0607142235.90", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607142235.90"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ikeda", 
        "givenName": "Toshio", 
        "id": "sg:person.0737512614.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737512614.15"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Saeki", 
        "givenName": "Keiichi", 
        "id": "sg:person.01027170254.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027170254.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kubo", 
        "givenName": "Hideyuki", 
        "id": "sg:person.01075303454.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075303454.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan", 
          "id": "http://www.grid.ac/institutes/grid.419280.6", 
          "name": [
            "National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kikuchi", 
        "givenName": "Tateki", 
        "id": "sg:person.011064726622.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011064726622.01"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "1994", 
    "datePublishedReg": "1994-01-01", 
    "description": "We have tested the fusogenic properties of cleaved and uncleaved spike (S) protein of mutine coronavirus (MCV) JHMV variant cl-2 by expressing the S protein by recombinant vaccinia viruses (RVVs). The amino acid sequence of the putative cleavage site of cl-2 S protein, Arg-Arg-Ala-Arg-Arg, was replaced by Arg-Thr-Ala-Leu-Glu by in vitro mutagenesis of cl-2 S gene. The RVVs having cl-2 S gene [RVV t(+)] or mutated cl-2 S gene [RVV t(-)] were tested for their ability to induce fusion as well as cleavability in DBT cells. After inoculation with RVV t(+) onto DBT cells, the fusion formation was first observed at 8 h postinoculation (p.i.) and spread throughout the whole culture by 24 h. In cells infected with RVV t(-), fusion appeared by 2 h and most of cells were fused by 30 h p.i. The S protein and its cleavage products were detected in DBT cells expressing wild type S protein. However, no cleavage products of the S protein were detected in RVV t(-) infected cells producing mutated S protein, even though fusion was clearly visible. These results suggest that the cleavage event of JHMV-S protein of MCV is not a prerequisite for fusion formation, but that it enhances fusion.", 
    "editor": [
      {
        "familyName": "Laude", 
        "givenName": "Hubert", 
        "type": "Person"
      }, 
      {
        "familyName": "Vautherot", 
        "givenName": "Jean-Fran\u00e7ois", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4615-2996-5_27", 
    "inLanguage": "en", 
    "isAccessibleForFree": true, 
    "isPartOf": {
      "isbn": [
        "978-1-4613-6305-7", 
        "978-1-4615-2996-5"
      ], 
      "name": "Coronaviruses", 
      "type": "Book"
    }, 
    "keywords": [
      "S gene", 
      "S protein", 
      "recombinant vaccinia virus", 
      "DBT cells", 
      "spike protein", 
      "fusogenic properties", 
      "putative cleavage site", 
      "murine coronavirus JHMV", 
      "cleavage products", 
      "Arg-Thr", 
      "fusion formation", 
      "cleavage events", 
      "Ala-Arg", 
      "Arg-Arg", 
      "cleavage site", 
      "genes", 
      "protein", 
      "Ala-Leu", 
      "vaccinia virus", 
      "cells", 
      "fusion", 
      "mutagenesis", 
      "whole culture", 
      "sequence", 
      "inoculation", 
      "Glu", 
      "Arg", 
      "CL-2", 
      "formation", 
      "cleavability", 
      "virus", 
      "sites", 
      "JHMV", 
      "culture", 
      "postinoculation", 
      "products", 
      "prerequisite", 
      "ability", 
      "events", 
      "results", 
      "properties", 
      "MCV", 
      "uncleaved spike (S) protein", 
      "mutine coronavirus (MCV) JHMV variant cl-2", 
      "coronavirus (MCV) JHMV variant cl-2", 
      "JHMV variant cl-2", 
      "variant cl-2", 
      "cl-2 S protein", 
      "cl-2 S gene", 
      "RVV t", 
      "wild type S protein", 
      "type S protein", 
      "protein of MCV", 
      "Coronavirus JHMV"
    ], 
    "name": "Fusogenic Properties of Uncleaved Spike Protein of Murine Coronavirus JHMV", 
    "pagination": "171-175", 
    "productId": [
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1001030813"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4615-2996-5_27"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "8209726"
        ]
      }
    ], 
    "publisher": {
      "name": "Springer Nature", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4615-2996-5_27", 
      "https://app.dimensions.ai/details/publication/pub.1001030813"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2022-01-01T19:12", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-springernature-scigraph/baseset/20220101/entities/gbq_results/chapter/chapter_2.jsonl", 
    "type": "Chapter", 
    "url": "https://doi.org/10.1007/978-1-4615-2996-5_27"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2996-5_27'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2996-5_27'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2996-5_27'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2996-5_27'


 

This table displays all metadata directly associated to this object as RDF triples.

211 TRIPLES      23 PREDICATES      96 URIs      90 LITERALS      24 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4615-2996-5_27 schema:about N0368605df6eb4b39881eaa4c30f9101f
2 N060c39b86d1c4011b914105761211398
3 N08cab4a302ad4e1c939a8426991ec522
4 N0a006604ab9944b0a1f313ca70e5d203
5 N23c5c1a9c7b84709ba4cb578cdf625af
6 N373fbad285a640299e90f1d8abda36af
7 N3f9836c2135340589121a2d6be8109b4
8 N5f4daaacefda48bab228b9f6f7611e42
9 N61bab1eaeb6b4aaaacf8245d735ee45d
10 N6ae28fb8f7e24900a6226c005ab37a2d
11 N802428b3c6be4613b83cfbc021c36ac9
12 N9d9704070dad4efc817f3f3f7f49f00b
13 Nb1d6eb294dc944cdbdf39b9d704aa2b8
14 Nb5ed1b2cc2ff4777b9311441e047b8f9
15 Nb9d8f42467fa405caf584f26ff3b2151
16 Nee1fe1450f6045bc8860bdf41524dbb3
17 anzsrc-for:11
18 schema:author N828b023dbf6342648abd6a23c91c10ba
19 schema:datePublished 1994
20 schema:datePublishedReg 1994-01-01
21 schema:description We have tested the fusogenic properties of cleaved and uncleaved spike (S) protein of mutine coronavirus (MCV) JHMV variant cl-2 by expressing the S protein by recombinant vaccinia viruses (RVVs). The amino acid sequence of the putative cleavage site of cl-2 S protein, Arg-Arg-Ala-Arg-Arg, was replaced by Arg-Thr-Ala-Leu-Glu by in vitro mutagenesis of cl-2 S gene. The RVVs having cl-2 S gene [RVV t(+)] or mutated cl-2 S gene [RVV t(-)] were tested for their ability to induce fusion as well as cleavability in DBT cells. After inoculation with RVV t(+) onto DBT cells, the fusion formation was first observed at 8 h postinoculation (p.i.) and spread throughout the whole culture by 24 h. In cells infected with RVV t(-), fusion appeared by 2 h and most of cells were fused by 30 h p.i. The S protein and its cleavage products were detected in DBT cells expressing wild type S protein. However, no cleavage products of the S protein were detected in RVV t(-) infected cells producing mutated S protein, even though fusion was clearly visible. These results suggest that the cleavage event of JHMV-S protein of MCV is not a prerequisite for fusion formation, but that it enhances fusion.
22 schema:editor N60328f8f09054ad09e75ff8f91f7cda9
23 schema:genre chapter
24 schema:inLanguage en
25 schema:isAccessibleForFree true
26 schema:isPartOf N2458efa39d7b4acd884fd07631d3dd6f
27 schema:keywords Ala-Arg
28 Ala-Leu
29 Arg
30 Arg-Arg
31 Arg-Thr
32 CL-2
33 Coronavirus JHMV
34 DBT cells
35 Glu
36 JHMV
37 JHMV variant cl-2
38 MCV
39 RVV t
40 S gene
41 S protein
42 ability
43 cells
44 cl-2 S gene
45 cl-2 S protein
46 cleavability
47 cleavage events
48 cleavage products
49 cleavage site
50 coronavirus (MCV) JHMV variant cl-2
51 culture
52 events
53 formation
54 fusion
55 fusion formation
56 fusogenic properties
57 genes
58 inoculation
59 murine coronavirus JHMV
60 mutagenesis
61 mutine coronavirus (MCV) JHMV variant cl-2
62 postinoculation
63 prerequisite
64 products
65 properties
66 protein
67 protein of MCV
68 putative cleavage site
69 recombinant vaccinia virus
70 results
71 sequence
72 sites
73 spike protein
74 type S protein
75 uncleaved spike (S) protein
76 vaccinia virus
77 variant cl-2
78 virus
79 whole culture
80 wild type S protein
81 schema:name Fusogenic Properties of Uncleaved Spike Protein of Murine Coronavirus JHMV
82 schema:pagination 171-175
83 schema:productId N0d244b96fe8a4dfebd95cc90dc9d5d4a
84 N4b840c17820245378e889f9e1878c2ac
85 N853d82b243b24278b86b1f19937704f6
86 schema:publisher Nca946197d7e64ee8a25f22f0995427fc
87 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001030813
88 https://doi.org/10.1007/978-1-4615-2996-5_27
89 schema:sdDatePublished 2022-01-01T19:12
90 schema:sdLicense https://scigraph.springernature.com/explorer/license/
91 schema:sdPublisher Nc94b3aed73cf41978df93350ff1579fb
92 schema:url https://doi.org/10.1007/978-1-4615-2996-5_27
93 sgo:license sg:explorer/license/
94 sgo:sdDataset chapters
95 rdf:type schema:Chapter
96 N0368605df6eb4b39881eaa4c30f9101f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
97 schema:name Molecular Sequence Data
98 rdf:type schema:DefinedTerm
99 N060c39b86d1c4011b914105761211398 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Endopeptidases
101 rdf:type schema:DefinedTerm
102 N08cab4a302ad4e1c939a8426991ec522 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name Tumor Cells, Cultured
104 rdf:type schema:DefinedTerm
105 N0a006604ab9944b0a1f313ca70e5d203 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
106 schema:name Mice
107 rdf:type schema:DefinedTerm
108 N0d244b96fe8a4dfebd95cc90dc9d5d4a schema:name dimensions_id
109 schema:value pub.1001030813
110 rdf:type schema:PropertyValue
111 N1ce9c6ffb96f490cb6a2f6b53ce3466a rdf:first sg:person.0737512614.15
112 rdf:rest Na894dc3339854d48b02fcb433b06bd28
113 N23c5c1a9c7b84709ba4cb578cdf625af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Membrane Glycoproteins
115 rdf:type schema:DefinedTerm
116 N2458efa39d7b4acd884fd07631d3dd6f schema:isbn 978-1-4613-6305-7
117 978-1-4615-2996-5
118 schema:name Coronaviruses
119 rdf:type schema:Book
120 N32dadc24fab74a5bb7908b9366147e63 schema:familyName Laude
121 schema:givenName Hubert
122 rdf:type schema:Person
123 N373fbad285a640299e90f1d8abda36af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
124 schema:name Murine hepatitis virus
125 rdf:type schema:DefinedTerm
126 N3f9836c2135340589121a2d6be8109b4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
127 schema:name Spike Glycoprotein, Coronavirus
128 rdf:type schema:DefinedTerm
129 N4b840c17820245378e889f9e1878c2ac schema:name pubmed_id
130 schema:value 8209726
131 rdf:type schema:PropertyValue
132 N5f4daaacefda48bab228b9f6f7611e42 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
133 schema:name Viral Envelope Proteins
134 rdf:type schema:DefinedTerm
135 N60328f8f09054ad09e75ff8f91f7cda9 rdf:first N32dadc24fab74a5bb7908b9366147e63
136 rdf:rest Nbaf696a007cc4d70b3de398e890ba83f
137 N61bab1eaeb6b4aaaacf8245d735ee45d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
138 schema:name Amino Acid Sequence
139 rdf:type schema:DefinedTerm
140 N6ae28fb8f7e24900a6226c005ab37a2d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
141 schema:name Cytopathogenic Effect, Viral
142 rdf:type schema:DefinedTerm
143 N802428b3c6be4613b83cfbc021c36ac9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Protein Processing, Post-Translational
145 rdf:type schema:DefinedTerm
146 N828b023dbf6342648abd6a23c91c10ba rdf:first sg:person.0607142235.90
147 rdf:rest N1ce9c6ffb96f490cb6a2f6b53ce3466a
148 N853d82b243b24278b86b1f19937704f6 schema:name doi
149 schema:value 10.1007/978-1-4615-2996-5_27
150 rdf:type schema:PropertyValue
151 N8c13be786e494b2f87fa51447a911092 rdf:first sg:person.011064726622.01
152 rdf:rest rdf:nil
153 N9d9704070dad4efc817f3f3f7f49f00b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Base Sequence
155 rdf:type schema:DefinedTerm
156 Na894dc3339854d48b02fcb433b06bd28 rdf:first sg:person.01027170254.41
157 rdf:rest Nac3badbaf4fc4c588cf42541eddcfb97
158 Nac3badbaf4fc4c588cf42541eddcfb97 rdf:first sg:person.01075303454.54
159 rdf:rest N8c13be786e494b2f87fa51447a911092
160 Nb1d6eb294dc944cdbdf39b9d704aa2b8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
161 schema:name Mutagenesis, Site-Directed
162 rdf:type schema:DefinedTerm
163 Nb5ed1b2cc2ff4777b9311441e047b8f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
164 schema:name Cell Fusion
165 rdf:type schema:DefinedTerm
166 Nb9d8f42467fa405caf584f26ff3b2151 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Astrocytoma
168 rdf:type schema:DefinedTerm
169 Nbaf696a007cc4d70b3de398e890ba83f rdf:first Ncb8983d9471f4584970e5f557d0e89f8
170 rdf:rest rdf:nil
171 Nc94b3aed73cf41978df93350ff1579fb schema:name Springer Nature - SN SciGraph project
172 rdf:type schema:Organization
173 Nca946197d7e64ee8a25f22f0995427fc schema:name Springer Nature
174 rdf:type schema:Organisation
175 Ncb8983d9471f4584970e5f557d0e89f8 schema:familyName Vautherot
176 schema:givenName Jean-François
177 rdf:type schema:Person
178 Nee1fe1450f6045bc8860bdf41524dbb3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
179 schema:name Animals
180 rdf:type schema:DefinedTerm
181 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
182 schema:name Medical and Health Sciences
183 rdf:type schema:DefinedTerm
184 sg:person.01027170254.41 schema:affiliation grid-institutes:grid.419280.6
185 schema:familyName Saeki
186 schema:givenName Keiichi
187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01027170254.41
188 rdf:type schema:Person
189 sg:person.01075303454.54 schema:affiliation grid-institutes:grid.419280.6
190 schema:familyName Kubo
191 schema:givenName Hideyuki
192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075303454.54
193 rdf:type schema:Person
194 sg:person.011064726622.01 schema:affiliation grid-institutes:grid.419280.6
195 schema:familyName Kikuchi
196 schema:givenName Tateki
197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011064726622.01
198 rdf:type schema:Person
199 sg:person.0607142235.90 schema:affiliation grid-institutes:grid.419280.6
200 schema:familyName Taguchi
201 schema:givenName Fumihiro
202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0607142235.90
203 rdf:type schema:Person
204 sg:person.0737512614.15 schema:affiliation grid-institutes:grid.419280.6
205 schema:familyName Ikeda
206 schema:givenName Toshio
207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0737512614.15
208 rdf:type schema:Person
209 grid-institutes:grid.419280.6 schema:alternateName National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan
210 schema:name National Institute of Neuroscience, NCNP, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187, Japan
211 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...