Mechanisms Regulating Nucleocapsid Formation of the Hepatitis B Viruses View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1993

AUTHORS

Ralf Bartenschlager , Heinz Schaller

ABSTRACT

The hepatitis B viruses are a group of small enveloped DNA viruses which are characterized by a distinct liver tropism and a narrow host range. The most important member of the hepadnavirus group is the human pathogenic hepatitis B virus (HBV; Dane et al., 1970). In addition, four animal hepatitis B viruses have been described. The woodchuck hepatitis B virus (WHV; Summers et al., 1978), the ground squirrel hepatitis B virus (GSHV; Marion et al., 1980), the duck hepatitis B virus (DHBV; Mason et al., 1980) and the heron hepatitis B virus (HHBV; Sprengel et al., 1988). Characteristic for this virus group is their mode of replication which includes the reverse transcription of an RNA genome. For this reason, hepadnaviruses are classified, along with retroviruses, as viral retroelements. However, while in retroviral replication the onset of DNA synthesis occurs after infection of the host cell, DNA synthesis in hepadnaviruses commences before release of virus particles. Therefore, retrovirus particles contain an RNA genome, hepadnavirus particles a DNA genome, leading to their classification as pararetroviruses. More... »

PAGES

49-66

Book

TITLE

Regulation of Gene Expression in Animal Viruses

ISBN

978-1-4613-6271-5
978-1-4615-2928-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-2928-6_5

DOI

http://dx.doi.org/10.1007/978-1-4615-2928-6_5

DIMENSIONS

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