Non-Invasive Measurements of the Cerebral Steady-State Glucose Concentration and Transport in Humans by 13C Nuclear Magnetic Resonance View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1993

AUTHORS

Rolf Gruetter , Edward J. Novotny , Susan D. Boulware , Douglas L. Rothman , Graeme F. Mason , Gerald I. Shulman , William V. Tamborlane , Robert G. Shulman

ABSTRACT

Glucose transport across the blood-brain barrier (BBB) has been shown to be a carrier-mediated, saturable process of the facilitated diffusion type (4). The cerebral steady-state glucose concentration depends on the kinetic properties of transport and is lower than in blood. Direct measurement of brain glucose is not possible in humans by non-invasive techniques using radioactive tracers because the signal of labeled glucose cannot be distinguished from that of its metabolic products. More... »

PAGES

35-40

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-2920-0_7

DOI

http://dx.doi.org/10.1007/978-1-4615-2920-0_7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1017629792

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8333347


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