Specificity in RNA: Protein Interactions; the Recognition of Escherichia Coli Glutamine tRNA View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1993

AUTHORS

M. John Rogers , Ivana Weygand-Durašević , Etienne Schwob , Joyce M. Sherman , Kelley C. Rogers , H. -Ulrich Thomann , Lee A. Sylvers , Martina Jahn , Hachiro Inokuchi , Eiko Ohtsuka , Dieter Söll

ABSTRACT

A major element ensuring the accuracy of translation of the genetic code is the recognition of tRNA by its cognate aminoacyl-tRNA synthetase. The tRNA molecule assumes many of the unusual elements of RNA structure (Delarue and Moras, 1989), and presumably this flexibility and variety in structure leads to the role of tRNA in other metabolic functions additional to protein synthesis (Sö11, 1993). The application of a variety of genetic, biochemical and biophysical techniques have been used to elucidate factors determining the accuracy of the recognition by Escherichia coli glutaminyl-tRNA synthetase (G1nRS) for tRNAG1n, and this system is probably one of the best understood tRNA:aminoacyl-tRNA synthetase systems (Söll, 1990), resulting in the first RNA-protein structure determined at the molecular level (Rould et al., 1989; Rould et al., 1991). This review will focus on our current understanding of this RNA:protein interaction. More... »

PAGES

47-58

Book

TITLE

The Translational Apparatus

ISBN

978-1-4613-6021-6
978-1-4615-2407-6

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-2407-6_5

DOI

http://dx.doi.org/10.1007/978-1-4615-2407-6_5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1039393723


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Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2407-6_5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2407-6_5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2407-6_5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2407-6_5'


 

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299 https://www.grid.ac/institutes/grid.47100.32 schema:alternateName Yale University
300 schema:name Department of Molecular Biophysics and Biochemistry, Yale University, 06511, New Haven, CT, USA
301 rdf:type schema:Organization
 




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