Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1995

AUTHORS

Alastair Aitken , Steve Howell , David Jones , Joel Madrazo , Harry Martin , Yasmina Patel , Karen Robinson

ABSTRACT

A method for analysing isoforms of 14-3-3 on acid-urea gels is also described. This permits the complete separation of all major isoforms and their unequivocal identification by a range of isoform specific antisera. The activity of recombinant 14-3- 3 and isoforms renatured by a novel method after separation by reverse phase HPLC are compared. The effects of diacylglycerol and the phorbol ester, PMA (phorbol 1 2-myristate 13 acetate) on the inhibition suggest that one of the sites of interaction of 14-3-3 may be the cysteine-rich (Cl) domain in PKC. More... »

PAGES

41-49

Book

TITLE

Signal Transduction Mechanisms

ISBN

978-1-4613-5833-6
978-1-4615-2015-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4615-2015-3_5

DOI

http://dx.doi.org/10.1007/978-1-4615-2015-3_5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005026351


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0904", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Chemical Engineering", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/09", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Engineering", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Aitken", 
        "givenName": "Alastair", 
        "id": "sg:person.01152554741.55", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152554741.55"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Howell", 
        "givenName": "Steve", 
        "id": "sg:person.012177662462.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012177662462.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jones", 
        "givenName": "David", 
        "id": "sg:person.01265004336.11", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265004336.11"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Madrazo", 
        "givenName": "Joel", 
        "id": "sg:person.01015415054.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015415054.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Martin", 
        "givenName": "Harry", 
        "id": "sg:person.0632250330.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632250330.86"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Patel", 
        "givenName": "Yasmina", 
        "id": "sg:person.01063530254.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063530254.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "The Francis Crick Institute", 
          "id": "https://www.grid.ac/institutes/grid.451388.3", 
          "name": [
            "Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Robinson", 
        "givenName": "Karen", 
        "id": "sg:person.01216671136.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216671136.94"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1992.tb16946.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000515886"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1994.0031", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000879974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.81.12.3622", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003148702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/44594a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003856893", 
          "https://doi.org/10.1038/44594a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1471-4159.1994.63062259.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003872311"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2320559", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004692157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2320559", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004692157"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(92)80384-s", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004987737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1993.tb18297.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009913745"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1990.tb19138.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010026650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(83)90030-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010069888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(83)90030-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010069888"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1982.tb05904.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010156385"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(93)80356-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011539802"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(92)81257-m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012555047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2860807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012690063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2860807", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012690063"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1993.1346", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013588079"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/355833a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013980896", 
          "https://doi.org/10.1038/355833a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ptr.2650010412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017434247"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00163762", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019658143", 
          "https://doi.org/10.1007/bf00163762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00163762", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019658143", 
          "https://doi.org/10.1007/bf00163762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(92)90394-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024267280"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(92)90394-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024267280"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-291x(05)80046-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025425959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.6.2320", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025822714"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(92)90339-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025873514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(92)90339-b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025873514"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-313x.1992.tb00151.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026470904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/361315a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027742268", 
          "https://doi.org/10.1038/361315a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/0-89603-268-x:39", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027867248", 
          "https://doi.org/10.1385/0-89603-268-x:39"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0968-0004(87)90082-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028155085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.19.7084", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029123689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(92)80557-w", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033876582"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(84)80976-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034113352"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/rcm.1290070812", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035892760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(91)90136-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037137854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(91)90136-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037137854"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(94)90048-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037200121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4889(94)90048-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037200121"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2840399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037818498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2840399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037818498"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(87)81194-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038579406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(94)90068-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039557355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(94)90068-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039557355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/334661a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040491061", 
          "https://doi.org/10.1038/334661a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3010305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044607291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3010305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044607291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0014-5793(92)80426-h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045270488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2910329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051994416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2910329", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051994416"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00121a043", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055161704"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2990853", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056720085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2990853", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056720085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1089/dna.1994.13.629", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059251377"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.7939645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062650664"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8036497", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062652027"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.8036498", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062652028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076105428", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077025136", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077614533", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/j.1460-2075.1984.tb01913.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1081682200"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995", 
    "datePublishedReg": "1995-01-01", 
    "description": "A method for analysing isoforms of 14-3-3 on acid-urea gels is also described. This permits the complete separation of all major isoforms and their unequivocal identification by a range of isoform specific antisera. The activity of recombinant 14-3- 3 and isoforms renatured by a novel method after separation by reverse phase HPLC are compared. The effects of diacylglycerol and the phorbol ester, PMA (phorbol 1 2-myristate 13 acetate) on the inhibition suggest that one of the sites of interaction of 14-3-3 may be the cysteine-rich (Cl) domain in PKC.", 
    "editor": [
      {
        "familyName": "Barnes", 
        "givenName": "Junor A.", 
        "type": "Person"
      }, 
      {
        "familyName": "Coore", 
        "givenName": "Haldane G.", 
        "type": "Person"
      }, 
      {
        "familyName": "Mohammed", 
        "givenName": "Abdul H.", 
        "type": "Person"
      }, 
      {
        "familyName": "Sharma", 
        "givenName": "Rajendra K.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4615-2015-3_5", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4613-5833-6", 
        "978-1-4615-2015-3"
      ], 
      "name": "Signal Transduction Mechanisms", 
      "type": "Book"
    }, 
    "name": "Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C", 
    "pagination": "41-49", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4615-2015-3_5"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "17f33ba30ab1156d7f40cd931079038fc2358fdcf30aa14fe61816f9aba32be6"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1005026351"
        ]
      }
    ], 
    "publisher": {
      "location": "Boston, MA", 
      "name": "Springer US", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4615-2015-3_5", 
      "https://app.dimensions.ai/details/publication/pub.1005026351"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T19:06", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8684_00000246.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4615-2015-3_5"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2015-3_5'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2015-3_5'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2015-3_5'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4615-2015-3_5'


 

This table displays all metadata directly associated to this object as RDF triples.

272 TRIPLES      23 PREDICATES      76 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4615-2015-3_5 schema:about anzsrc-for:09
2 anzsrc-for:0904
3 schema:author N7a5bd7d69d0949eaa33c5b02a638605d
4 schema:citation sg:pub.10.1007/bf00163762
5 sg:pub.10.1038/334661a0
6 sg:pub.10.1038/355833a0
7 sg:pub.10.1038/361315a0
8 sg:pub.10.1038/44594a0
9 sg:pub.10.1385/0-89603-268-x:39
10 https://app.dimensions.ai/details/publication/pub.1076105428
11 https://app.dimensions.ai/details/publication/pub.1077025136
12 https://app.dimensions.ai/details/publication/pub.1077614533
13 https://doi.org/10.1002/j.1460-2075.1984.tb01913.x
14 https://doi.org/10.1002/ptr.2650010412
15 https://doi.org/10.1002/rcm.1290070812
16 https://doi.org/10.1006/jmbi.1993.1346
17 https://doi.org/10.1006/jmbi.1994.0031
18 https://doi.org/10.1016/0014-5793(84)80976-x
19 https://doi.org/10.1016/0014-5793(87)81194-8
20 https://doi.org/10.1016/0014-5793(92)80384-s
21 https://doi.org/10.1016/0014-5793(92)80426-h
22 https://doi.org/10.1016/0014-5793(92)80557-w
23 https://doi.org/10.1016/0014-5793(92)81257-m
24 https://doi.org/10.1016/0014-5793(93)80356-y
25 https://doi.org/10.1016/0167-4781(83)90030-1
26 https://doi.org/10.1016/0167-4781(91)90136-a
27 https://doi.org/10.1016/0167-4889(94)90048-5
28 https://doi.org/10.1016/0378-1119(92)90394-5
29 https://doi.org/10.1016/0378-1119(94)90068-x
30 https://doi.org/10.1016/0968-0004(87)90082-x
31 https://doi.org/10.1016/0968-0004(92)90339-b
32 https://doi.org/10.1016/s0006-291x(05)80046-4
33 https://doi.org/10.1021/bi00121a043
34 https://doi.org/10.1042/bj2320559
35 https://doi.org/10.1042/bj2840399
36 https://doi.org/10.1042/bj2860807
37 https://doi.org/10.1042/bj2910329
38 https://doi.org/10.1042/bj2990853
39 https://doi.org/10.1042/bj3010305
40 https://doi.org/10.1046/j.1471-4159.1994.63062259.x
41 https://doi.org/10.1073/pnas.81.12.3622
42 https://doi.org/10.1073/pnas.85.19.7084
43 https://doi.org/10.1073/pnas.90.6.2320
44 https://doi.org/10.1089/dna.1994.13.629
45 https://doi.org/10.1111/j.1365-313x.1992.tb00151.x
46 https://doi.org/10.1111/j.1432-1033.1982.tb05904.x
47 https://doi.org/10.1111/j.1432-1033.1990.tb19138.x
48 https://doi.org/10.1111/j.1432-1033.1992.tb16946.x
49 https://doi.org/10.1111/j.1432-1033.1993.tb18297.x
50 https://doi.org/10.1126/science.7939645
51 https://doi.org/10.1126/science.8036497
52 https://doi.org/10.1126/science.8036498
53 schema:datePublished 1995
54 schema:datePublishedReg 1995-01-01
55 schema:description A method for analysing isoforms of 14-3-3 on acid-urea gels is also described. This permits the complete separation of all major isoforms and their unequivocal identification by a range of isoform specific antisera. The activity of recombinant 14-3- 3 and isoforms renatured by a novel method after separation by reverse phase HPLC are compared. The effects of diacylglycerol and the phorbol ester, PMA (phorbol 1 2-myristate 13 acetate) on the inhibition suggest that one of the sites of interaction of 14-3-3 may be the cysteine-rich (Cl) domain in PKC.
56 schema:editor N580f1884cfda4387b9a3d4c764d0413b
57 schema:genre chapter
58 schema:inLanguage en
59 schema:isAccessibleForFree false
60 schema:isPartOf Na34ed6a55a1b4b7296fb58ef516871f1
61 schema:name Post-translationally modified 14-3-3 isoforms and inhibition of protein kinase C
62 schema:pagination 41-49
63 schema:productId N4ca76e9284a6462c92401fac912ad79a
64 N68b0189c83fd4b39994e8685fd6b64c8
65 N8d62bc29335342a7986f9070120816cf
66 schema:publisher N9668833c47314c1d849f6aad5cdf5237
67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005026351
68 https://doi.org/10.1007/978-1-4615-2015-3_5
69 schema:sdDatePublished 2019-04-15T19:06
70 schema:sdLicense https://scigraph.springernature.com/explorer/license/
71 schema:sdPublisher N79ececd3efe041219f436323ae2043eb
72 schema:url http://link.springer.com/10.1007/978-1-4615-2015-3_5
73 sgo:license sg:explorer/license/
74 sgo:sdDataset chapters
75 rdf:type schema:Chapter
76 N0030d1c2b5eb4534a0c437cc0bafbbe6 rdf:first sg:person.01063530254.13
77 rdf:rest N10ddbf5d6b9a45858cefa67f00402511
78 N075a2f83940e4b678509ad52f6981f3a rdf:first sg:person.012177662462.48
79 rdf:rest Na57639d6e3f24bb6be47c93bbf7e1761
80 N10ddbf5d6b9a45858cefa67f00402511 rdf:first sg:person.01216671136.94
81 rdf:rest rdf:nil
82 N228474627761456bb85655b40e7e5f27 schema:familyName Mohammed
83 schema:givenName Abdul H.
84 rdf:type schema:Person
85 N340131eb049647cfa33e38e918c60186 schema:familyName Coore
86 schema:givenName Haldane G.
87 rdf:type schema:Person
88 N3931e07b9e354e9b9aaf6726c85904c4 rdf:first sg:person.01015415054.51
89 rdf:rest N3cd7be2506bf404c99636f31d0a25504
90 N39a9217e33bf48d1ae408a6002c8f686 rdf:first N340131eb049647cfa33e38e918c60186
91 rdf:rest Naccc9161a1c84b7bbff0a62e7353b712
92 N3cd7be2506bf404c99636f31d0a25504 rdf:first sg:person.0632250330.86
93 rdf:rest N0030d1c2b5eb4534a0c437cc0bafbbe6
94 N4ca76e9284a6462c92401fac912ad79a schema:name readcube_id
95 schema:value 17f33ba30ab1156d7f40cd931079038fc2358fdcf30aa14fe61816f9aba32be6
96 rdf:type schema:PropertyValue
97 N580f1884cfda4387b9a3d4c764d0413b rdf:first N95b2469294394920b701571936ba5645
98 rdf:rest N39a9217e33bf48d1ae408a6002c8f686
99 N68b0189c83fd4b39994e8685fd6b64c8 schema:name doi
100 schema:value 10.1007/978-1-4615-2015-3_5
101 rdf:type schema:PropertyValue
102 N79ececd3efe041219f436323ae2043eb schema:name Springer Nature - SN SciGraph project
103 rdf:type schema:Organization
104 N7a5bd7d69d0949eaa33c5b02a638605d rdf:first sg:person.01152554741.55
105 rdf:rest N075a2f83940e4b678509ad52f6981f3a
106 N83b6b0fdd969448ab64a9c25b0736b4b rdf:first Nc0c3992c10bc4cc9bcab39c1db941a10
107 rdf:rest rdf:nil
108 N8d62bc29335342a7986f9070120816cf schema:name dimensions_id
109 schema:value pub.1005026351
110 rdf:type schema:PropertyValue
111 N95b2469294394920b701571936ba5645 schema:familyName Barnes
112 schema:givenName Junor A.
113 rdf:type schema:Person
114 N9668833c47314c1d849f6aad5cdf5237 schema:location Boston, MA
115 schema:name Springer US
116 rdf:type schema:Organisation
117 Na34ed6a55a1b4b7296fb58ef516871f1 schema:isbn 978-1-4613-5833-6
118 978-1-4615-2015-3
119 schema:name Signal Transduction Mechanisms
120 rdf:type schema:Book
121 Na57639d6e3f24bb6be47c93bbf7e1761 rdf:first sg:person.01265004336.11
122 rdf:rest N3931e07b9e354e9b9aaf6726c85904c4
123 Naccc9161a1c84b7bbff0a62e7353b712 rdf:first N228474627761456bb85655b40e7e5f27
124 rdf:rest N83b6b0fdd969448ab64a9c25b0736b4b
125 Nc0c3992c10bc4cc9bcab39c1db941a10 schema:familyName Sharma
126 schema:givenName Rajendra K.
127 rdf:type schema:Person
128 anzsrc-for:09 schema:inDefinedTermSet anzsrc-for:
129 schema:name Engineering
130 rdf:type schema:DefinedTerm
131 anzsrc-for:0904 schema:inDefinedTermSet anzsrc-for:
132 schema:name Chemical Engineering
133 rdf:type schema:DefinedTerm
134 sg:person.01015415054.51 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
135 schema:familyName Madrazo
136 schema:givenName Joel
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01015415054.51
138 rdf:type schema:Person
139 sg:person.01063530254.13 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
140 schema:familyName Patel
141 schema:givenName Yasmina
142 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01063530254.13
143 rdf:type schema:Person
144 sg:person.01152554741.55 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
145 schema:familyName Aitken
146 schema:givenName Alastair
147 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01152554741.55
148 rdf:type schema:Person
149 sg:person.01216671136.94 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
150 schema:familyName Robinson
151 schema:givenName Karen
152 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216671136.94
153 rdf:type schema:Person
154 sg:person.012177662462.48 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
155 schema:familyName Howell
156 schema:givenName Steve
157 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012177662462.48
158 rdf:type schema:Person
159 sg:person.01265004336.11 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
160 schema:familyName Jones
161 schema:givenName David
162 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265004336.11
163 rdf:type schema:Person
164 sg:person.0632250330.86 schema:affiliation https://www.grid.ac/institutes/grid.451388.3
165 schema:familyName Martin
166 schema:givenName Harry
167 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632250330.86
168 rdf:type schema:Person
169 sg:pub.10.1007/bf00163762 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019658143
170 https://doi.org/10.1007/bf00163762
171 rdf:type schema:CreativeWork
172 sg:pub.10.1038/334661a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040491061
173 https://doi.org/10.1038/334661a0
174 rdf:type schema:CreativeWork
175 sg:pub.10.1038/355833a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013980896
176 https://doi.org/10.1038/355833a0
177 rdf:type schema:CreativeWork
178 sg:pub.10.1038/361315a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027742268
179 https://doi.org/10.1038/361315a0
180 rdf:type schema:CreativeWork
181 sg:pub.10.1038/44594a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003856893
182 https://doi.org/10.1038/44594a0
183 rdf:type schema:CreativeWork
184 sg:pub.10.1385/0-89603-268-x:39 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027867248
185 https://doi.org/10.1385/0-89603-268-x:39
186 rdf:type schema:CreativeWork
187 https://app.dimensions.ai/details/publication/pub.1076105428 schema:CreativeWork
188 https://app.dimensions.ai/details/publication/pub.1077025136 schema:CreativeWork
189 https://app.dimensions.ai/details/publication/pub.1077614533 schema:CreativeWork
190 https://doi.org/10.1002/j.1460-2075.1984.tb01913.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1081682200
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1002/ptr.2650010412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017434247
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1002/rcm.1290070812 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035892760
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1006/jmbi.1993.1346 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013588079
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1006/jmbi.1994.0031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000879974
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1016/0014-5793(84)80976-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034113352
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1016/0014-5793(87)81194-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038579406
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1016/0014-5793(92)80384-s schema:sameAs https://app.dimensions.ai/details/publication/pub.1004987737
205 rdf:type schema:CreativeWork
206 https://doi.org/10.1016/0014-5793(92)80426-h schema:sameAs https://app.dimensions.ai/details/publication/pub.1045270488
207 rdf:type schema:CreativeWork
208 https://doi.org/10.1016/0014-5793(92)80557-w schema:sameAs https://app.dimensions.ai/details/publication/pub.1033876582
209 rdf:type schema:CreativeWork
210 https://doi.org/10.1016/0014-5793(92)81257-m schema:sameAs https://app.dimensions.ai/details/publication/pub.1012555047
211 rdf:type schema:CreativeWork
212 https://doi.org/10.1016/0014-5793(93)80356-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1011539802
213 rdf:type schema:CreativeWork
214 https://doi.org/10.1016/0167-4781(83)90030-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010069888
215 rdf:type schema:CreativeWork
216 https://doi.org/10.1016/0167-4781(91)90136-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1037137854
217 rdf:type schema:CreativeWork
218 https://doi.org/10.1016/0167-4889(94)90048-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037200121
219 rdf:type schema:CreativeWork
220 https://doi.org/10.1016/0378-1119(92)90394-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024267280
221 rdf:type schema:CreativeWork
222 https://doi.org/10.1016/0378-1119(94)90068-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039557355
223 rdf:type schema:CreativeWork
224 https://doi.org/10.1016/0968-0004(87)90082-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028155085
225 rdf:type schema:CreativeWork
226 https://doi.org/10.1016/0968-0004(92)90339-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1025873514
227 rdf:type schema:CreativeWork
228 https://doi.org/10.1016/s0006-291x(05)80046-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025425959
229 rdf:type schema:CreativeWork
230 https://doi.org/10.1021/bi00121a043 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055161704
231 rdf:type schema:CreativeWork
232 https://doi.org/10.1042/bj2320559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004692157
233 rdf:type schema:CreativeWork
234 https://doi.org/10.1042/bj2840399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037818498
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1042/bj2860807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012690063
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1042/bj2910329 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051994416
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1042/bj2990853 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056720085
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1042/bj3010305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044607291
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1046/j.1471-4159.1994.63062259.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003872311
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1073/pnas.81.12.3622 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003148702
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1073/pnas.85.19.7084 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029123689
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1073/pnas.90.6.2320 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025822714
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1089/dna.1994.13.629 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059251377
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1111/j.1365-313x.1992.tb00151.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026470904
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1111/j.1432-1033.1982.tb05904.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010156385
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1111/j.1432-1033.1990.tb19138.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010026650
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1111/j.1432-1033.1992.tb16946.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1000515886
261 rdf:type schema:CreativeWork
262 https://doi.org/10.1111/j.1432-1033.1993.tb18297.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009913745
263 rdf:type schema:CreativeWork
264 https://doi.org/10.1126/science.7939645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062650664
265 rdf:type schema:CreativeWork
266 https://doi.org/10.1126/science.8036497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652027
267 rdf:type schema:CreativeWork
268 https://doi.org/10.1126/science.8036498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062652028
269 rdf:type schema:CreativeWork
270 https://www.grid.ac/institutes/grid.451388.3 schema:alternateName The Francis Crick Institute
271 schema:name Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, NW7 1AA, UK
272 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...