Metabolomics Applications in Human Nutrition View Full Text


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Chapter Info

DATE

2012

AUTHORS

Hannelore Daniel , Manuela Sailer

ABSTRACT

Human metabolism is a continuum. It shifts constantly between anabolic conditions after food intake and catabolic states between meals or during extended starvation periods. At all times there is need of a constant supply of nutrients and metabolites for ATP production and of building blocks for the continuous remodeling of cellular structures. However, the sources of fuels used to maintain metabolic functions are variable (carbohydrates versus lipids versus proteins) depending on frequency of eating and fasting and the quantity and quality of food intake. The profile of the metabolites in any biological sample obtained, taken at any time is a snapshot of an ever-changing “integrated metabolome”. Human plasma, urine or breath metabolomes contain not only endogenously produced metabolites but also the nutrients and metabolites provided by the diet and, in addition, metabolites derived from the microbiota hosted in the human large intestine which are partly absorbed and appear later in blood and urine (Fig. 9.1). More... »

PAGES

125-137

References to SciGraph publications

Book

TITLE

Genetics Meets Metabolomics

ISBN

978-1-4614-1688-3
978-1-4614-1689-0

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4614-1689-0_9

DOI

http://dx.doi.org/10.1007/978-1-4614-1689-0_9

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012330867


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