The Occurrence of Melanoma and Its Relationship with Host, Lifestyle and Environmental Factors View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1983

AUTHORS

Ronald T. Acton , Charles M. Balch , Bruce O. Barger , Bruce Budowle , Rodney C. P. Go , Seng-Jaw Soong , Jeffrey M. Roseman

ABSTRACT

Human melanoma of the skin is a malignancy whose incidence is rapidly increasing in the United States as well as in other countries [1–7]. The highest melanoma mortality rate in the U.S. is found in Alabama [8]. In order to understand the reasons for this increased incidence, one must consider three major interacting factors, the constitutional makeup of the host, the lifestyle of the host and environmental exposure [9–11]. This review will look at the studies of each of these factors in an effort to better understand the etiology of melanoma. We have tried to consider the majority of reports which bear on this subject. However, some selection of data has obviously occurred, and we have relied heavily on the reviews of others to make certain points. Reference when appropriate is also made to our own data collected from patients, greater than 95% of whom reside in the State of Alabama, treated at the Melanoma Clinic of the University of Alabama in Birmingham (UAB). Finally, we will propose a model based on our review which, taking into account both host specific, environmental factors and their interactions, could explain the incidence of melanoma in most Caucasian populations. Provided the relative contributions of these three factors to the etiology of melanoma can be discerned, one should be able to identify highly susceptible individuals in the population and therefore suggest measures to alter lifestyle to minimize exposure to environmental agents. More... »

PAGES

151-182

References to SciGraph publications

Book

TITLE

Malignant Melanoma 1

ISBN

978-1-4613-3902-1
978-1-4613-3900-7

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-3900-7_7

DOI

http://dx.doi.org/10.1007/978-1-4613-3900-7_7

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034394823


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