The Acute Glomerulonephritis Syndrome View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1984

AUTHORS

Joel Neugarten , David S. Baldwin

ABSTRACT

The term acute glomerulonephritis syndrome refers to the clinical signs and symptoms which are typically observed in association with post-infectious diffuse endocapillary proliferation within glomeruli. The full-blown syndrome consists of the abrupt appearance of salt and water retention, edema, reduced urine output, circulatory congestion, hypertension, hematuria, proteinuria, and decreased filtration rate. Full expression of the syndrome does not necessarily occur in all instances of post-infectious glomerulonephritis. Urinary abnormalities, decreased filtration rate and fluid retention are practically invariable. When these clinical features were thought to occur uniquely with diffuse proliferation of mesangial and endothelial cells, polymorphonuclear inflammatory cell reaction and occasional extracapillary proliferation following infection, the simple term ‘acute nephritis’ was classically applied. As it became apparent, however, that many of these same clinical manifestations could at times characterize the onset of Berger’s IgA nephropathy, Henoch-Schönlein purpura, mixed essential cryoglobulinemia, Guillain-Barre-Strohl syndrome, systemic lupus erythematosis, idiopathic mesangiocapillary glomerulonephritis, and systemic vasculitis (1–3), the appellation acute glomerulonephritis syndrome appeared to be more appropriate. The following discussion deals primarily with the pathophysiology, clinical manifestations and therapy of the syndrome as it occurs in post-infectious diffuse endocapillary proliferative glomerulonephritis. More... »

PAGES

183-193

Book

TITLE

Therapy of Renal Diseases and Related Disorders

ISBN

978-1-4613-3809-3
978-1-4613-3807-9

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-3807-9_13

DOI

http://dx.doi.org/10.1007/978-1-4613-3807-9_13

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1030925702


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