Ontology type: schema:Chapter
1985
AUTHORSAllan McI. Mowat , Annette Borland , Delphine M. V. Parrott
ABSTRACTGraft-versus-host disease (GvHD) is the most important complication of allogeneic bone marrow transplantation (BMT) in humans and the associated intestinal damage is a major cause of morbidity and mortality in these patients1. If the intestinal consequences of GvHD are to be prevented or treated, it will be necessary to elucidate the pathogenic mechanisms which are responsible and to identify the nature of the alloantigenic stimuli. Although it has usually been assumed that cytotoxic T lymphocytes (CTL) cause the tissue damage during allograft rejection and in GvHD, recent evidence indicates that CTL may not be necessary for these phenomena2,3. More... »
PAGES531-538
Microenvironments in the Lymphoid System
ISBN
978-1-4612-9495-5
978-1-4613-2463-8
http://scigraph.springernature.com/pub.10.1007/978-1-4613-2463-8_65
DOIhttp://dx.doi.org/10.1007/978-1-4613-2463-8_65
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