Pathogenesis of the Intestinal Phase of the Graft-Versus-Host Reaction inn F1 Hybrid Mice View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1985

AUTHORS

Allan McI. Mowat , Annette Borland , Delphine M. V. Parrott

ABSTRACT

Graft-versus-host disease (GvHD) is the most important complication of allogeneic bone marrow transplantation (BMT) in humans and the associated intestinal damage is a major cause of morbidity and mortality in these patients1. If the intestinal consequences of GvHD are to be prevented or treated, it will be necessary to elucidate the pathogenic mechanisms which are responsible and to identify the nature of the alloantigenic stimuli. Although it has usually been assumed that cytotoxic T lymphocytes (CTL) cause the tissue damage during allograft rejection and in GvHD, recent evidence indicates that CTL may not be necessary for these phenomena2,3. More... »

PAGES

531-538

Book

TITLE

Microenvironments in the Lymphoid System

ISBN

978-1-4612-9495-5
978-1-4613-2463-8

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-2463-8_65

DOI

http://dx.doi.org/10.1007/978-1-4613-2463-8_65

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1013207112


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