Prostacyclin, EDRF and Atherosclerosis View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1988

AUTHORS

Salvador Moncada

ABSTRACT

The main metabolic product of the fatty acid arachidonic acid (AA) in vascular tissue is prostacyclin, a potent vasodilator and inhibitor of platelet aggregation (1). In contrast, in platelets AA is mainly converted to thromboxane A2, which is a potent vasoconstrictor and inducer of platelet aggregation. An imbalance in the formation or the interaction between these two AA metabolites has been implicated in the underlying process of various thrombotic conditions as well as of atherosclerosis (2). More... »

PAGES

1-11

Book

TITLE

Eicosanoids, Apolipoproteins, Lipoprotein Particles, and Atherosclerosis

ISBN

978-1-4612-8055-2
978-1-4613-0733-4

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-0733-4_1

DOI

http://dx.doi.org/10.1007/978-1-4613-0733-4_1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035258488

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/3066171


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