Immunological Findings in the CSF of HIV-1 Infected Patients View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1990

AUTHORS

A. De Rossi , P. Gallo , A. Amadori , M. G. Piccinno , A. Del Mistro , S. Pagni , M. L. Calabrô , L. Chieco-Bianchi , B. Tavolato

ABSTRACT

Both peripheral and central nervous system disorders have been described in patients with the acquired immunodeficiency syndrome (AIDS).1–8 Increasing evidence indicates that the human immunodeficiency virus type 1 (HIV-1) is neurotropic and infects the nervous system early in the course of systemic virus spread.9–14 Ultrastructural and hybridization analyses of brain tissue from AIDS patients have revealed that HIV-1 replication occurs predominantly in cells of macrophage/microglial lineage.15–16 However, the relationship between the neurological/psychiatric symptoms associated with HIV-1 infections of the central nervous system (CNS) and the HIV-1-induced immunological abnormalities at the cellular level is still unclear. More... »

PAGES

13-22

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-0607-8_2

DOI

http://dx.doi.org/10.1007/978-1-4613-0607-8_2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000107421


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