Vitamins C and E Alter the Response to Coronary Balloon Injury in the Pig View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1996

AUTHORS

Gilberto L. Nunes , Spencer B. King , Robert A. Redden , Steven R. Sigman , Bradford C. Berk , Demetrios S. Sgoutas , Michael B. Gravanis

ABSTRACT

Restenosis after percutaneous transluminal coronary angioplasty is the major limitation of the long-term success of this procedure (Holmes et al., 1984). The process of restenosis involves repair of vascular injury and remodeling of vessel architecture (Kuntz and Baim, 1993). Therapeutic interventions that improve vascular function may therefore be beneficial in the treatment of restenosis (Kuntz et al.) Antioxidants such as probucol and vitamins C and E have proved effective in improving endothelial function in hypercholesterolemia, inhibiting lipid accumulation in animal models of atherosclerosis and decreasing cardiovascular mortality in humans (Halliwell, 1989). More... »

PAGES

322-323

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4613-0355-8_72

DOI

http://dx.doi.org/10.1007/978-1-4613-0355-8_72

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003360596


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