Proclactin Regulation and Developmental Expression of a 37,000 Mr Protein in the Corpus Luteum View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

1991

AUTHORS

Constance T. Albarracin , Geula Gibori

ABSTRACT

Prolactin (PRL), a polypeptide hormone secreted by the anterior pituitary, has a diverse array of actions. In mammals, it acts on both the mammary gland and corpus luteum. In the mammary gland, PRL stimulates the expression of milk proteins, increasing both casein gene transcription and mRNA half life (1, 2). In the corpus luteum, PRL is essential for optimal growth and steroidogenesis resulting in the maintenance of high progesterone levels required for the normal progression of pregnancy (3). The corpus luteum thus provides a model that is highly and specifically responsive to PRL, allowing the systematic study of PRL action. In addition, progesterone levels provide a measurable focal endpoint of PRL action in the corpus luteum. More... »

PAGES

336-342

References to SciGraph publications

Book

TITLE

Signaling Mechanisms and Gene Expression in the Ovary

ISBN

978-1-4612-7830-6
978-1-4612-3200-1

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4612-3200-1_38

DOI

http://dx.doi.org/10.1007/978-1-4612-3200-1_38

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012717936


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