Neoadjuvant and Adjuvant Chemotherapy for Advanced Ovarian Cancer, Including Biological Agents View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2015

AUTHORS

Shelize S. Khakoo , Susana Banerjee

ABSTRACT

The majority of women with ovarian cancer continue to present at advanced stages and the overall 5-year survival rate remains just over 40 %. The principles of the initial management of advanced ovarian cancer consist of maximal cytoreductive surgery and platinum-based chemotherapy. Improvements in surgery and chemotherapy strategies have led to better clinical outcomes. However, disease recurrence and drug resistance present management challenges. Clinical trials evaluating the optimal schedule, mode of administration of established chemotherapy drugs and the integration of targeted agents have led to improvements in survival and practice change. This chapter provides an overview of the initial management of advanced ovarian cancer and the integration of targeted therapies in this setting. More... »

PAGES

441-453

Book

TITLE

Pelvic Cancer Surgery

ISBN

978-1-4471-4257-7
978-1-4471-4258-4

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4471-4258-4_41

DOI

http://dx.doi.org/10.1007/978-1-4471-4258-4_41

DIMENSIONS

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