A Notch-related Gene Located on the Long Arm of Human Chromosome 12 View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2002

AUTHORS

David Adamah , Paul J. Gokhale , James Walsh , Peter W. Andrews

ABSTRACT

Family and cytogenetic studies of testicular germ cell tumours (TGCT) suggest a strong genetic component in the aetiology of these tumours. We have focused upon genes that may play a key regulatory role in the development of germ cells. Following studies in the nematode worm, Caenorhabditis elegans [1], we have investigated the Notch gene family. Initial results indicate that members of the Notch family are expressed by primordial germ cells, and by seminoma and intratubular germ cell neoplasia, consistent with a possible role in tumour development (unpublished results). More... »

PAGES

30-31

Book

TITLE

Germ Cell Tumours V

ISBN

978-1-4471-3283-7
978-1-4471-3281-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4471-3281-3_3

DOI

http://dx.doi.org/10.1007/978-1-4471-3281-3_3

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1012364034


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