The Tumor Microenvironment View Full Text


Ontology type: schema:Book     


Book Info

DATE

2010

GENRE

Book

AUTHORS

Lissa Baird , Alexey Terskikh

PUBLISHER

Springer New York

ABSTRACT

Recent advances in stem cell and developmental neurobiology have uncovered new perspectives from which we investigate various forms of cancer. Specifically, the hypothesis at tumors are comprised of a subpopulation of malignant cells similar to stem cells is of great interest to scientists and clinicians and has been dubbed the cancer stem cell hypothesis. The region where this is most relevant is within the brain. Cancer stem cells have been isolated from brain tumors that exhibit characteristics of differentiation and proliferation normally seen only in neural stem cells. These cancer stem cells may be responsible for tumor origin, survival and proliferation. Furthermore, these cells must be considered within their immediate microenvironment when investigating mechanisms of tumorgenesis. Evidence of brain tumor stem cells will be reviewed along with the role of tumor environment as the context within which these cells should be understood. More... »

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4419-6615-5

DOI

http://dx.doi.org/10.1007/978-1-4419-6615-5

ISBN

978-1-4419-6614-8 | 978-1-4419-6615-5

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1029185662

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/20455496


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