Soft Tissue Tumors View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2010-10-28

AUTHORS

Leona A. Doyle , Alessandra F. Nascimento

ABSTRACT

Soft tissue tumors are composed of a large heterogenous group of mesenchymal neoplasms that are classified accordingly to the normal tissue counterpart. However, morphologic overlap between tumors may happen, and neoplasms may be further divided into histologic broad categories: round cell tumors, spindle cell tumors, epithelioid tumors, myxoid tumors, and pleomorphic tumors. In addition, soft tissue neoplasms have been shown to have reproducible numerical and structural chromosomal abnormalities that can be very promptly recognized by conventional cytogenetics and/or by other molecular tests, such as fluorescence in situ hybridization (FISH). The diagnosis of these neoplasms is based on the histologic recognition of the lesion as well as expression of immunoperoxidase studies in certain tumors, and characteristic cytogenetic findings. In contrast to most other solid tumors, in particular epithelial neoplasms, where the American Joint Committee on Cancer (AJCC) staging plays a pivotal role in the prognosis, in soft tissue neoplasms is dictated by natural history of the tumors and treatment. More... »

PAGES

995-1045

Book

TITLE

Essentials of Anatomic Pathology

ISBN

978-1-4419-6042-9
978-1-4419-6043-6

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4419-6043-6_22

DOI

http://dx.doi.org/10.1007/978-1-4419-6043-6_22

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1032871383


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