Prenatal Famine Exposure and Long-Term Consequences for Anthropometry and Adult Health View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2012

AUTHORS

Tessa Roseboom , Rebecca Painter , Susanne de Rooij

ABSTRACT

This paper describes the findings from a cohort study of 2,414 people born around the time of the Dutch famine. We found more coronary heart disease, a more atherogenic lipid profile, disturbed blood coagulation, and increased stress responsiveness among those exposed to famine in early gestation. Women exposed to famine in early gestation were more obese and had an increased risk of breast cancer. People exposed to famine in mid gestation had more microalbuminuria and obstructive airway disease. Exposure to famine during any stage of gestation was associated with glucose intolerance. Also, women who had been exposed to famine prenatally were more reproductively successful: they started reproducing at an earlier age, had more children, more twins, and were less likely to remain childless. The effects of prenatal famine exposure did not appear to be restricted to those exposed to it prenatally: also, their children appeared to be less healthy. These findings show that maternal undernutrition during gestation has important effects on health in later life, but that the effects on health depend on its timing during gestation. Early gestation seems to be an especially vulnerable period. Adequate dietary advice to women before and during pregnancy seems a promising strategy in preventing chronic diseases in future generations. More... »

PAGES

1021-1032

Book

TITLE

Handbook of Anthropometry

ISBN

978-1-4419-1787-4
978-1-4419-1788-1

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4419-1788-1_61

DOI

http://dx.doi.org/10.1007/978-1-4419-1788-1_61

DIMENSIONS

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