Strategies for Epigenome Analysis View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009

AUTHORS

A.B. Brinkman , H.G. Stunnenberg

ABSTRACT

The eukaryotic genome is packaged into nucleosomes, which form the basal unit of chromatin, the physiological form of DNA within the nucleus. Apart from its function in compacting the immense nuclear DNA molecules, chromatin also serves as a platform onto which multiple signalling pathways converge to cooperate in determining the expression status of mRNAs and other (non-coding) RNA molecules. Epigenetic profile analysis aims to determine what changes on the nucleosomes cooperate to establish and maintain DNA sequence-independent heritable traits such as those determining cell identity. More... »

PAGES

3-18

Book

TITLE

Epigenomics

ISBN

978-1-4020-9186-5
978-1-4020-9187-2

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4020-9187-2_1

DOI

http://dx.doi.org/10.1007/978-1-4020-9187-2_1

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024108666


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