Small RNA Technologies: siRNA, miRNA, antagomiR, Target Mimicry, miRNA Sponge and miRNA Profiling View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2008

AUTHORS

Guiliang Tang , Yu Xiang , Zhensheng Kang , Venugopal Mendu , Xiaohu Tang , Xiaoyun Jia , Qi-Jun Chen , Xiaoqing Tang

ABSTRACT

The breakthrough discovery of RNA interference (RNAi) by Fire and Mello in 1998 has ushered in a new wave of RNA-based technological advances in the life sciences. Small RNAs, namely small interfering RNA (siRNA) and microRNA (miRNA), not only play key roles in down regulating gene expression, controlling growth and development, stress response, and various diseases, but also serve as essential tools for the study of gene functions. In this chapter, we provide an overview of the technological aspects of siRNAs and miRNAs and common methods for studying their functions. More... »

PAGES

17-33

References to SciGraph publications

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  • Book

    TITLE

    Current Perspectives in microRNAs (miRNA)

    ISBN

    978-1-4020-8532-1
    978-1-4020-8533-8

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/978-1-4020-8533-8_2

    DOI

    http://dx.doi.org/10.1007/978-1-4020-8533-8_2

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1052024337


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