Effects of Photoexcited Fullerene C60-Composites in Normal and Transformed Cells View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2008

AUTHORS

S. V. Prylutska , I. I. Grynyuk , O. P. Matyshevska , A. A. Golub , A. P. Burlaka , Yu. I. Prylutskyy , U. Ritter , P. Scharff

ABSTRACT

The supramolecular composites containing fullerenes C60 immobilized at nanosilica were used for the design of the molecular systems that can be an effective agent in cancer photodynamic therapy (PDT). In particular, it was shown that photoexcited fullerene C60-containing composites decrease viability of transformed cells, intensify the process of lipid peroxidation (LPO) in cell membranes and accumulation of low-molecular weight DNA fragments, and also decrease the activity of electron-transport chain of mitochondria. More... »

PAGES

123-137

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4020-6845-4_6

DOI

http://dx.doi.org/10.1007/978-1-4020-6845-4_6

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1051638468


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