EX VIVO Expansion of CD34+ Cells in Stemline™ II Hematopoietic Stem Cell Expansion Medium Generates a Large Population of Functional ... View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2007

AUTHORS

Stacy L. Leugers , Daniel W. Allison , Ying Liang , Carol Swiderski , Gary Van Zant , Laurel M. Donahue

ABSTRACT

Hematopoietic stem cell replacement therapy is an area of research lacking an optimal culture system that allows for the ex vivo expansion of CD34+ cells for transplant. The necessity for expansion is due to the lack of sufficient material from umbilical cord blood (UCB), the preferred source of CD34+ cells. The final composition of the expanded cells is also very important to a successful transplant. The material must contain both early and late progenitor cells to ensure the long-term engraftment that is required in patients with genetic disorders and those that have gone through high dose chemotherapy. More... »

PAGES

339-341

Book

TITLE

Cell Technology for Cell Products

ISBN

978-1-4020-5475-4

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-1-4020-5476-1_55

DOI

http://dx.doi.org/10.1007/978-1-4020-5476-1_55

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1047451253


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biochemistry and Cell Biology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Sigma-Aldrich (United States)", 
          "id": "https://www.grid.ac/institutes/grid.277695.8", 
          "name": [
            "Cell Culture R&D, Sigma-Aldrich, St. Louis, MO, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Leugers", 
        "givenName": "Stacy L.", 
        "id": "sg:person.012560503232.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012560503232.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sigma-Aldrich (United States)", 
          "id": "https://www.grid.ac/institutes/grid.277695.8", 
          "name": [
            "Cell Culture R&D, Sigma-Aldrich, St. Louis, MO, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Allison", 
        "givenName": "Daniel W.", 
        "id": "sg:person.011414634636.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011414634636.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Kentucky", 
          "id": "https://www.grid.ac/institutes/grid.266539.d", 
          "name": [
            "College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Liang", 
        "givenName": "Ying", 
        "id": "sg:person.01175443767.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175443767.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Kentucky", 
          "id": "https://www.grid.ac/institutes/grid.266539.d", 
          "name": [
            "College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Swiderski", 
        "givenName": "Carol", 
        "id": "sg:person.01046021666.74", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046021666.74"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Kentucky", 
          "id": "https://www.grid.ac/institutes/grid.266539.d", 
          "name": [
            "College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Van Zant", 
        "givenName": "Gary", 
        "id": "sg:person.01014133010.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014133010.81"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Sigma-Aldrich (United States)", 
          "id": "https://www.grid.ac/institutes/grid.277695.8", 
          "name": [
            "Cell Culture R&D, Sigma-Aldrich, St. Louis, MO, United States"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Donahue", 
        "givenName": "Laurel M.", 
        "id": "sg:person.0636710175.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636710175.65"
        ], 
        "type": "Person"
      }
    ], 
    "datePublished": "2007", 
    "datePublishedReg": "2007-01-01", 
    "description": "Hematopoietic stem cell replacement therapy is an area of research lacking an optimal culture system that allows for the ex vivo expansion of CD34+ cells for transplant. The necessity for expansion is due to the lack of sufficient material from umbilical cord blood (UCB), the preferred source of CD34+ cells. The final composition of the expanded cells is also very important to a successful transplant. The material must contain both early and late progenitor cells to ensure the long-term engraftment that is required in patients with genetic disorders and those that have gone through high dose chemotherapy.", 
    "editor": [
      {
        "familyName": "Smith", 
        "givenName": "Rodney", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/978-1-4020-5476-1_55", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-1-4020-5475-4"
      ], 
      "name": "Cell Technology for Cell Products", 
      "type": "Book"
    }, 
    "name": "EX VIVO Expansion of CD34+ Cells in Stemline\u2122 II Hematopoietic Stem Cell Expansion Medium Generates a Large Population of Functional Early and Late Progenitor Cells", 
    "pagination": "339-341", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/978-1-4020-5476-1_55"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e20b16c99fec285f0039ba182d546ea9ad1b3a31788c9dd943f1e90886a12ff2"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1047451253"
        ]
      }
    ], 
    "publisher": {
      "location": "Dordrecht", 
      "name": "Springer Netherlands", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/978-1-4020-5476-1_55", 
      "https://app.dimensions.ai/details/publication/pub.1047451253"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T11:23", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8660_00000081.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/978-1-4020-5476-1_55"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/978-1-4020-5476-1_55'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/978-1-4020-5476-1_55'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/978-1-4020-5476-1_55'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/978-1-4020-5476-1_55'


 

This table displays all metadata directly associated to this object as RDF triples.

102 TRIPLES      22 PREDICATES      27 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/978-1-4020-5476-1_55 schema:about anzsrc-for:06
2 anzsrc-for:0601
3 schema:author Ne4cf3a9c68c741f6b4c3f108a7ae0a28
4 schema:datePublished 2007
5 schema:datePublishedReg 2007-01-01
6 schema:description Hematopoietic stem cell replacement therapy is an area of research lacking an optimal culture system that allows for the ex vivo expansion of CD34+ cells for transplant. The necessity for expansion is due to the lack of sufficient material from umbilical cord blood (UCB), the preferred source of CD34+ cells. The final composition of the expanded cells is also very important to a successful transplant. The material must contain both early and late progenitor cells to ensure the long-term engraftment that is required in patients with genetic disorders and those that have gone through high dose chemotherapy.
7 schema:editor Ncfe9ef85fcee49ebaa204cb463225b62
8 schema:genre chapter
9 schema:inLanguage en
10 schema:isAccessibleForFree false
11 schema:isPartOf N88e6f2291af6405ea09649c84ebd56b4
12 schema:name EX VIVO Expansion of CD34+ Cells in Stemline™ II Hematopoietic Stem Cell Expansion Medium Generates a Large Population of Functional Early and Late Progenitor Cells
13 schema:pagination 339-341
14 schema:productId N3a95b05809814ae1b1142e95e0bb786a
15 N932cdb8ea55c4f7389c66e62e1a269e0
16 Ncc0c78ecbcc34bc298bdd7a7428b90c5
17 schema:publisher N3165190e15874a15a208182ac92b18aa
18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047451253
19 https://doi.org/10.1007/978-1-4020-5476-1_55
20 schema:sdDatePublished 2019-04-15T11:23
21 schema:sdLicense https://scigraph.springernature.com/explorer/license/
22 schema:sdPublisher Nad3b83a9a59e4db19fe8207896a120aa
23 schema:url http://link.springer.com/10.1007/978-1-4020-5476-1_55
24 sgo:license sg:explorer/license/
25 sgo:sdDataset chapters
26 rdf:type schema:Chapter
27 N3165190e15874a15a208182ac92b18aa schema:location Dordrecht
28 schema:name Springer Netherlands
29 rdf:type schema:Organisation
30 N3a95b05809814ae1b1142e95e0bb786a schema:name dimensions_id
31 schema:value pub.1047451253
32 rdf:type schema:PropertyValue
33 N8296000c1b3c4e79ad4aba8e7ec1f3ae rdf:first sg:person.01014133010.81
34 rdf:rest N9be7dfba38fe43a3a33109617f11b270
35 N88e6f2291af6405ea09649c84ebd56b4 schema:isbn 978-1-4020-5475-4
36 schema:name Cell Technology for Cell Products
37 rdf:type schema:Book
38 N8e65048532ae441292d387ff125513b9 schema:familyName Smith
39 schema:givenName Rodney
40 rdf:type schema:Person
41 N932cdb8ea55c4f7389c66e62e1a269e0 schema:name doi
42 schema:value 10.1007/978-1-4020-5476-1_55
43 rdf:type schema:PropertyValue
44 N9be7dfba38fe43a3a33109617f11b270 rdf:first sg:person.0636710175.65
45 rdf:rest rdf:nil
46 Nad3b83a9a59e4db19fe8207896a120aa schema:name Springer Nature - SN SciGraph project
47 rdf:type schema:Organization
48 Nc3fb4c6fb5134397b454e51810e73ecf rdf:first sg:person.011414634636.58
49 rdf:rest Ndad87d6902ac49faba952add17a7e89b
50 Ncc0c78ecbcc34bc298bdd7a7428b90c5 schema:name readcube_id
51 schema:value e20b16c99fec285f0039ba182d546ea9ad1b3a31788c9dd943f1e90886a12ff2
52 rdf:type schema:PropertyValue
53 Ncfe9ef85fcee49ebaa204cb463225b62 rdf:first N8e65048532ae441292d387ff125513b9
54 rdf:rest rdf:nil
55 Ndad87d6902ac49faba952add17a7e89b rdf:first sg:person.01175443767.75
56 rdf:rest Nea740b2b73ea4d3aaa97bc652dff4f21
57 Ne4cf3a9c68c741f6b4c3f108a7ae0a28 rdf:first sg:person.012560503232.08
58 rdf:rest Nc3fb4c6fb5134397b454e51810e73ecf
59 Nea740b2b73ea4d3aaa97bc652dff4f21 rdf:first sg:person.01046021666.74
60 rdf:rest N8296000c1b3c4e79ad4aba8e7ec1f3ae
61 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
62 schema:name Biological Sciences
63 rdf:type schema:DefinedTerm
64 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
65 schema:name Biochemistry and Cell Biology
66 rdf:type schema:DefinedTerm
67 sg:person.01014133010.81 schema:affiliation https://www.grid.ac/institutes/grid.266539.d
68 schema:familyName Van Zant
69 schema:givenName Gary
70 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01014133010.81
71 rdf:type schema:Person
72 sg:person.01046021666.74 schema:affiliation https://www.grid.ac/institutes/grid.266539.d
73 schema:familyName Swiderski
74 schema:givenName Carol
75 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046021666.74
76 rdf:type schema:Person
77 sg:person.011414634636.58 schema:affiliation https://www.grid.ac/institutes/grid.277695.8
78 schema:familyName Allison
79 schema:givenName Daniel W.
80 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011414634636.58
81 rdf:type schema:Person
82 sg:person.01175443767.75 schema:affiliation https://www.grid.ac/institutes/grid.266539.d
83 schema:familyName Liang
84 schema:givenName Ying
85 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01175443767.75
86 rdf:type schema:Person
87 sg:person.012560503232.08 schema:affiliation https://www.grid.ac/institutes/grid.277695.8
88 schema:familyName Leugers
89 schema:givenName Stacy L.
90 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012560503232.08
91 rdf:type schema:Person
92 sg:person.0636710175.65 schema:affiliation https://www.grid.ac/institutes/grid.277695.8
93 schema:familyName Donahue
94 schema:givenName Laurel M.
95 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636710175.65
96 rdf:type schema:Person
97 https://www.grid.ac/institutes/grid.266539.d schema:alternateName University of Kentucky
98 schema:name College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, United States
99 rdf:type schema:Organization
100 https://www.grid.ac/institutes/grid.277695.8 schema:alternateName Sigma-Aldrich (United States)
101 schema:name Cell Culture R&D, Sigma-Aldrich, St. Louis, MO, United States
102 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...