Molecular Regulation of the State of Embryonic Stem Cells View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2009-05-02

AUTHORS

Yuko Fujiwara , Stuart H. Orkin

ABSTRACT

Pluripotency is a defining feature of embryonic stem cells (ESCs). A mechanistic understanding of pluripotency should shed light on fundamental aspects of development. In this chapter, we review the extrinsic factors, protein, and gene regulatory networks and epigenetics of ESCs. With the availability of human ESCs and the capacity to reprogram somatic cells to a pluripotent state, we hope that a comprehensive description of the control of pluripotency in ESCs will contribute to the use of these cells in regenerative medicine. More... »

PAGES

33-60

Book

TITLE

Stem Cells and Cancer

ISBN

978-0-387-89610-6
978-0-387-89611-3

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/978-0-387-89611-3_2

DOI

http://dx.doi.org/10.1007/978-0-387-89611-3_2

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1003160849


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