The Natural History of ADP-Ribosyltransferases and the ADP-Ribosylation System View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2014

AUTHORS

L. Aravind , Dapeng Zhang , Robson F. de Souza , Swadha Anand , Lakshminarayan M. Iyer

ABSTRACT

Catalysis of NAD(+)-dependent ADP-ribosylation of proteins, nucleic acids, or small molecules has evolved in at least three structurally unrelated superfamilies of enzymes, namely ADP-ribosyltransferase (ART), the Sirtuins, and probably TM1506. Of these, the ART superfamily is the most diverse in terms of structure, active site residues, and targets that they modify. The primary diversification of the ART superfamily occurred in the context of diverse bacterial conflict systems, wherein ARTs play both offensive and defensive roles. These include toxin-antitoxin systems, virus-host interactions, intraspecific antagonism (polymorphic toxins), symbiont/parasite effectors/toxins, resistance to antibiotics, and repair of RNAs cleaved in conflicts. ARTs evolving in these systems have been repeatedly acquired by lateral transfer throughout eukaryotic evolution, starting from the PARP family, which was acquired prior to the last eukaryotic common ancestor. They were incorporated into eukaryotic regulatory/epigenetic control systems (e.g., PARP family and NEURL4), and also used as defensive (e.g., pierisin and CARP-1 families) or immunity-related proteins (e.g., Gig2-like ARTs). The ADP-ribosylation system also includes other domains, such as the Macro, ADP-ribosyl glycohydrolase, NADAR, and ADP-ribosyl cyclase, which appear to have initially diversified in bacterial conflict-related systems. Unlike ARTs, sirtuins appear to have a much smaller presence in conflict-related systems. More... »

PAGES

3-32

References to SciGraph publications

  • 2011-09. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase in NATURE
  • 2012-12. Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics in BIOLOGY DIRECT
  • 1997. Sequence and Structural Links between Distant ADP-Ribosyltransferase Families in ADP-RIBOSYLATION IN ANIMAL TISSUES
  • 1994-12. Reversible ADP-ribosylation as a mechanism of enzyme regulation in procaryotes in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 2013-03. TAC from Mycobacterium tuberculosis: a paradigm for stress-responsive toxin–antitoxin systems controlled by SecB-like chaperones in CELL STRESS AND CHAPERONES
  • 2009-09. A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-04. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine in NATURE
  • 1999-10-01. Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2005-12. In silico characterization of the family of PARP-like poly(ADP-ribosyl)transferases (pARTs) in BMC GENOMICS
  • 2011-07. ADP-ribosylation of arginine in AMINO ACIDS
  • 2010-12. Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes in BMC EVOLUTIONARY BIOLOGY
  • 2007-05. A type III effector ADP-ribosylates RNA-binding proteins and quells plant immunity in NATURE
  • 1994-12. Poly(ADP-ribose): Historical perspective in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/82_2014_414

    DOI

    http://dx.doi.org/10.1007/82_2014_414

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1030999188

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/25027823


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