PDGF-BB stabilisiert VEGF165-induzierte »leaky vessels« nach zell-basiertem Gentransfer in vivo View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2006

AUTHORS

T. Spanholtz , S. Söllner , C. Niedworok , A. Maichle , W. Lindenmaier , S. Krüger , B. Stöcklhuber , P. Mailänder , H -G. Machens

ABSTRACT

Durch die kombinierte Expression von VEGF165 und PDGF-BB kann eine stabile Angiogenese in vivo induziert werden, die deutlich über das zeitliche Ausmaß der zell-basierten Proteinexpression nach adenoviralem Gentransfer im Gewebe hinausgeht. Die Ausbildung instabiler »leaky vessels« wird durch die Koexpression von VEGF165 und PDGF-BB in diesem Modell verhindert.

PAGES

383-385

Book

TITLE

Chirurgisches Forum 2006

ISBN

978-3-540-32480-5
978-3-540-34668-5

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/3-540-34668-6_131

DOI

http://dx.doi.org/10.1007/3-540-34668-6_131

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048164240


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "author": [
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Spanholtz", 
        "givenName": "T.", 
        "id": "sg:person.01054637466.14", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054637466.14"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "S\u00f6llner", 
        "givenName": "S.", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niedworok", 
        "givenName": "C.", 
        "id": "sg:person.0606135475.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606135475.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maichle", 
        "givenName": "A.", 
        "id": "sg:person.01331541575.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331541575.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "GBF German Research Centre for Biotechnology", 
          "id": "https://www.grid.ac/institutes/grid.418123.d", 
          "name": [
            "Gesellschaft f\u00fcr Biotechnologische Forschung (GBF), Braunschweig"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lindenmaier", 
        "givenName": "W.", 
        "id": "sg:person.0746137143.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746137143.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Schleswig-Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kr\u00fcger", 
        "givenName": "S.", 
        "id": "sg:person.01344670267.46", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344670267.46"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Institut f\u00fcr Pathologie, Universit\u00e4tsklinikum Schleswig-Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "St\u00f6cklhuber", 
        "givenName": "B.", 
        "id": "sg:person.07506535623.75", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07506535623.75"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mail\u00e4nder", 
        "givenName": "P.", 
        "id": "sg:person.0645225705.60", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645225705.60"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "name": [
            "Klinik f\u00fcr Plastische und Handchirurgie, Zentrum f\u00fcr Schwerbrandverletzte, Universit\u00e4tsklinikum Schleswig- Holstein, Campus L\u00fcbeck, L\u00fcbeck"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Machens", 
        "givenName": "H -G.", 
        "id": "sg:person.01277176063.94", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277176063.94"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/978-3-642-19024-7_66", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027570438", 
          "https://doi.org/10.1007/978-3-642-19024-7_66"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm848", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037320126", 
          "https://doi.org/10.1038/nm848"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm848", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037320126", 
          "https://doi.org/10.1038/nm848"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2006", 
    "datePublishedReg": "2006-01-01", 
    "description": "Durch die kombinierte Expression von VEGF165 und PDGF-BB kann eine stabile Angiogenese in vivo induziert werden, die deutlich \u00fcber das zeitliche Ausma\u00df der zell-basierten Proteinexpression nach adenoviralem Gentransfer im Gewebe hinausgeht. Die Ausbildung instabiler \u00bbleaky vessels\u00ab wird durch die Koexpression von VEGF165 und PDGF-BB in diesem Modell verhindert.", 
    "editor": [
      {
        "familyName": "Saeger", 
        "givenName": "H. -D.", 
        "type": "Person"
      }, 
      {
        "familyName": "Jauch", 
        "givenName": "K. -W.", 
        "type": "Person"
      }, 
      {
        "familyName": "Bauer", 
        "givenName": "H.", 
        "type": "Person"
      }
    ], 
    "genre": "chapter", 
    "id": "sg:pub.10.1007/3-540-34668-6_131", 
    "inLanguage": [
      "de"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": {
      "isbn": [
        "978-3-540-32480-5", 
        "978-3-540-34668-5"
      ], 
      "name": "Chirurgisches Forum 2006", 
      "type": "Book"
    }, 
    "name": "PDGF-BB stabilisiert VEGF165-induzierte \u00bbleaky vessels\u00ab nach zell-basiertem Gentransfer in vivo", 
    "pagination": "383-385", 
    "productId": [
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1007/3-540-34668-6_131"
        ]
      }, 
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "e5725107e642e263a425992fb4bc719067065f78117a46ed9298788bf3255eee"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1048164240"
        ]
      }
    ], 
    "publisher": {
      "location": "Berlin, Heidelberg", 
      "name": "Springer Berlin Heidelberg", 
      "type": "Organisation"
    }, 
    "sameAs": [
      "https://doi.org/10.1007/3-540-34668-6_131", 
      "https://app.dimensions.ai/details/publication/pub.1048164240"
    ], 
    "sdDataset": "chapters", 
    "sdDatePublished": "2019-04-15T23:29", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8695_00000554.jsonl", 
    "type": "Chapter", 
    "url": "http://link.springer.com/10.1007/3-540-34668-6_131"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/3-540-34668-6_131'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/3-540-34668-6_131'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/3-540-34668-6_131'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/3-540-34668-6_131'


 

This table displays all metadata directly associated to this object as RDF triples.

146 TRIPLES      22 PREDICATES      27 URIs      20 LITERALS      8 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1007/3-540-34668-6_131 schema:author N4d7ffd7c49cd4683854ccf05543c26c8
2 schema:citation sg:pub.10.1007/978-3-642-19024-7_66
3 sg:pub.10.1038/nm848
4 schema:datePublished 2006
5 schema:datePublishedReg 2006-01-01
6 schema:description Durch die kombinierte Expression von VEGF165 und PDGF-BB kann eine stabile Angiogenese in vivo induziert werden, die deutlich über das zeitliche Ausmaß der zell-basierten Proteinexpression nach adenoviralem Gentransfer im Gewebe hinausgeht. Die Ausbildung instabiler »leaky vessels« wird durch die Koexpression von VEGF165 und PDGF-BB in diesem Modell verhindert.
7 schema:editor N3e68d055b2094e9898bacc78032e6e04
8 schema:genre chapter
9 schema:inLanguage de
10 schema:isAccessibleForFree false
11 schema:isPartOf Ne236fb8859c04599a4cd716215a5f064
12 schema:name PDGF-BB stabilisiert VEGF165-induzierte »leaky vessels« nach zell-basiertem Gentransfer in vivo
13 schema:pagination 383-385
14 schema:productId N31af352175d44b60872e46a59fd4be2d
15 N66b5201040674e0e98de5d466140075a
16 Nb9b8d213105b4c8d80a962438d688a4f
17 schema:publisher N7d84ebde292b48ca8c34086b2dff7b4a
18 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048164240
19 https://doi.org/10.1007/3-540-34668-6_131
20 schema:sdDatePublished 2019-04-15T23:29
21 schema:sdLicense https://scigraph.springernature.com/explorer/license/
22 schema:sdPublisher Nccc8f5f273a6400793877ead64b488e2
23 schema:url http://link.springer.com/10.1007/3-540-34668-6_131
24 sgo:license sg:explorer/license/
25 sgo:sdDataset chapters
26 rdf:type schema:Chapter
27 N03812c9c2d024388973fc68dc971aaae schema:affiliation N4d190d5446d2437e9f876fd87280d42f
28 schema:familyName Söllner
29 schema:givenName S.
30 rdf:type schema:Person
31 N214762f5331347f1a2e0d04afe6e31a7 rdf:first N914d7055aebc443894a35d5a67af6b63
32 rdf:rest rdf:nil
33 N229be2d98bf943eca62c90130b210961 rdf:first sg:person.0606135475.12
34 rdf:rest N5ebae3741df54760a59eb0ca78704cd1
35 N26c7b9ce2c5d420d8e0bd2ded57ff169 schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
36 rdf:type schema:Organization
37 N2a15f4c29622458b9623feaf4a3c27a5 schema:familyName Jauch
38 schema:givenName K. -W.
39 rdf:type schema:Person
40 N2b4a73a2b21f4c26b44d49240fda65c3 schema:familyName Saeger
41 schema:givenName H. -D.
42 rdf:type schema:Person
43 N31af352175d44b60872e46a59fd4be2d schema:name doi
44 schema:value 10.1007/3-540-34668-6_131
45 rdf:type schema:PropertyValue
46 N3e68d055b2094e9898bacc78032e6e04 rdf:first N2b4a73a2b21f4c26b44d49240fda65c3
47 rdf:rest N9b8512addc1e4c76b798583801e20156
48 N4d190d5446d2437e9f876fd87280d42f schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
49 rdf:type schema:Organization
50 N4d7ffd7c49cd4683854ccf05543c26c8 rdf:first sg:person.01054637466.14
51 rdf:rest N61a289bbd8d04d3fb48012c69025662c
52 N5ebae3741df54760a59eb0ca78704cd1 rdf:first sg:person.01331541575.37
53 rdf:rest N9d25316101a8487d9b98ce78990ad322
54 N61a289bbd8d04d3fb48012c69025662c rdf:first N03812c9c2d024388973fc68dc971aaae
55 rdf:rest N229be2d98bf943eca62c90130b210961
56 N66b5201040674e0e98de5d466140075a schema:name dimensions_id
57 schema:value pub.1048164240
58 rdf:type schema:PropertyValue
59 N7d84ebde292b48ca8c34086b2dff7b4a schema:location Berlin, Heidelberg
60 schema:name Springer Berlin Heidelberg
61 rdf:type schema:Organisation
62 N80cb08fd591e4488bc4a0771340d81e8 schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
63 rdf:type schema:Organization
64 N8f9c539479d9413181ddaec30be77400 rdf:first sg:person.0645225705.60
65 rdf:rest Nf83ad1584f57451ea4d71107f6ec884f
66 N914d7055aebc443894a35d5a67af6b63 schema:familyName Bauer
67 schema:givenName H.
68 rdf:type schema:Person
69 N9b8512addc1e4c76b798583801e20156 rdf:first N2a15f4c29622458b9623feaf4a3c27a5
70 rdf:rest N214762f5331347f1a2e0d04afe6e31a7
71 N9d25316101a8487d9b98ce78990ad322 rdf:first sg:person.0746137143.23
72 rdf:rest Ncede5b51068941b78153cec9f17d751c
73 Nb225da955185434a8546cb4f7ef10d68 schema:name Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck
74 rdf:type schema:Organization
75 Nb379a92abd9f409b9e1743898007fd6f schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
76 rdf:type schema:Organization
77 Nb9b8d213105b4c8d80a962438d688a4f schema:name readcube_id
78 schema:value e5725107e642e263a425992fb4bc719067065f78117a46ed9298788bf3255eee
79 rdf:type schema:PropertyValue
80 Nbb0924cc74914da693fe138841f5f5ab rdf:first sg:person.07506535623.75
81 rdf:rest N8f9c539479d9413181ddaec30be77400
82 Nccc8f5f273a6400793877ead64b488e2 schema:name Springer Nature - SN SciGraph project
83 rdf:type schema:Organization
84 Ncede5b51068941b78153cec9f17d751c rdf:first sg:person.01344670267.46
85 rdf:rest Nbb0924cc74914da693fe138841f5f5ab
86 Nddc5c9ce7c56491bbe6fd44c3864fd42 schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
87 rdf:type schema:Organization
88 Ne236fb8859c04599a4cd716215a5f064 schema:isbn 978-3-540-32480-5
89 978-3-540-34668-5
90 schema:name Chirurgisches Forum 2006
91 rdf:type schema:Book
92 Ne70b1701dd754e10ab272d844cfd4987 schema:name Klinik für Plastische und Handchirurgie, Zentrum für Schwerbrandverletzte, Universitätsklinikum Schleswig- Holstein, Campus Lübeck, Lübeck
93 rdf:type schema:Organization
94 Nf3894bda6f574d53868222fb15025605 schema:name Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck
95 rdf:type schema:Organization
96 Nf83ad1584f57451ea4d71107f6ec884f rdf:first sg:person.01277176063.94
97 rdf:rest rdf:nil
98 sg:person.01054637466.14 schema:affiliation Nb379a92abd9f409b9e1743898007fd6f
99 schema:familyName Spanholtz
100 schema:givenName T.
101 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01054637466.14
102 rdf:type schema:Person
103 sg:person.01277176063.94 schema:affiliation N80cb08fd591e4488bc4a0771340d81e8
104 schema:familyName Machens
105 schema:givenName H -G.
106 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277176063.94
107 rdf:type schema:Person
108 sg:person.01331541575.37 schema:affiliation N26c7b9ce2c5d420d8e0bd2ded57ff169
109 schema:familyName Maichle
110 schema:givenName A.
111 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01331541575.37
112 rdf:type schema:Person
113 sg:person.01344670267.46 schema:affiliation Nf3894bda6f574d53868222fb15025605
114 schema:familyName Krüger
115 schema:givenName S.
116 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01344670267.46
117 rdf:type schema:Person
118 sg:person.0606135475.12 schema:affiliation Ne70b1701dd754e10ab272d844cfd4987
119 schema:familyName Niedworok
120 schema:givenName C.
121 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606135475.12
122 rdf:type schema:Person
123 sg:person.0645225705.60 schema:affiliation Nddc5c9ce7c56491bbe6fd44c3864fd42
124 schema:familyName Mailänder
125 schema:givenName P.
126 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0645225705.60
127 rdf:type schema:Person
128 sg:person.0746137143.23 schema:affiliation https://www.grid.ac/institutes/grid.418123.d
129 schema:familyName Lindenmaier
130 schema:givenName W.
131 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746137143.23
132 rdf:type schema:Person
133 sg:person.07506535623.75 schema:affiliation Nb225da955185434a8546cb4f7ef10d68
134 schema:familyName Stöcklhuber
135 schema:givenName B.
136 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07506535623.75
137 rdf:type schema:Person
138 sg:pub.10.1007/978-3-642-19024-7_66 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027570438
139 https://doi.org/10.1007/978-3-642-19024-7_66
140 rdf:type schema:CreativeWork
141 sg:pub.10.1038/nm848 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037320126
142 https://doi.org/10.1038/nm848
143 rdf:type schema:CreativeWork
144 https://www.grid.ac/institutes/grid.418123.d schema:alternateName GBF German Research Centre for Biotechnology
145 schema:name Gesellschaft für Biotechnologische Forschung (GBF), Braunschweig
146 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...