Inorganic Radionuclides for Nuclear Medicine Therapy View Full Text


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Chapter Info

DATE

2012-08-03

AUTHORS

Yun-Sang Lee , Jae Min Jeong

ABSTRACT

The most commonly used radionuclides for therapy are beta emitters which have shorter penetration depth than gamma emitters. Alpha or Auger emitters also are studied for higher efficiency within shorter range. Most of these radionuclides for therapy are metals and these should be labeled to specific ligands such as peptides or proteins via bifunctional chelating agents conjugated to them. Selection of the bifunctional chelating agents generally based on the dissociation constants with target metallic radionuclides. For the improved efficiency of radionuclide therapy, intensive studies about development of new ligands and labeling methods are required. More... »

PAGES

151-163

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/174_2012_704

DOI

http://dx.doi.org/10.1007/174_2012_704

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027629388


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