Equipping Physiologists with an Informatics Tool Chest: Toward an Integerated Mitochondrial Phenome View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2016-12-20

AUTHORS

Anders Olav Garlid , Jennifer S. Polson , Keith D. Garlid , Henning Hermjakob , Peipei Ping

ABSTRACT

Understanding the complex involvement of mitochondrial biology in disease development often requires the acquisition, analysis, and integration of large-scale molecular and phenotypic data. An increasing number of bioinformatics tools are currently employed to aid in mitochondrial investigations, most notably in predicting or corroborating the spatial and temporal dynamics of mitochondrial molecules, in retrieving structural data of mitochondrial components, and in aggregating as well as transforming mitochondrial centric biomedical knowledge. With the increasing prevalence of complex Big Data from omics experiments and clinical cohorts, informatics tools have become indispensable in our quest to understand mitochondrial physiology and pathology. Here we present an overview of the various informatics resources that are helping researchers explore this vital organelle and gain insights into its form, function, and dynamics. More... »

PAGES

377-401

Identifiers

URI

http://scigraph.springernature.com/pub.10.1007/164_2016_93

DOI

http://dx.doi.org/10.1007/164_2016_93

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1034222291

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/27995389


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