Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation View Full Text


Ontology type: schema:Chapter     


Chapter Info

DATE

2013

AUTHORS

Claudia Papewalis , Daniela Topolar , Barbara Götz , Stefan Schönberger , Dagmar Dilloo

ABSTRACT

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option in hematopoietic disorders, immunodeficiencies and leukemia. To date graft-versus-host disease (GvHD) represents a life-threatening complication even if associated with beneficial antileukemic reactivity. GvHD is the clinical manifestation of donor cells reacting against host tissue. Because of their ability to facilitate endogenous repair and to attenuate inflammation, MSC have evolved as a highly attractive cellular therapeutic in allo-HSCT. Here we report on the clinical experience in the use of MSC to enhance engraftment and prevent and treat acute and chronic GvHD. In early clinical trials, MSC have shown considerable benefit in the setting of manifest GvHD. These encouraging results warrant further exploration. More... »

PAGES

131-62

References to SciGraph publications

  • 2003-07. Umbilical-cord blood transplantation for the treatment of cancer in NATURE REVIEWS CANCER
  • 2008-03. Low-dose MTX for the treatment of acute and chronic graft-versus-host disease in children in BONE MARROW TRANSPLANTATION
  • 2012-01. Mesenchymal stromal cells for cell therapy: besides supporting hematopoiesis in INTERNATIONAL JOURNAL OF HEMATOLOGY
  • 2009-10. Guidelines for preventing infectious complications among hematopoietic cell transplant recipients: a global perspective in BONE MARROW TRANSPLANTATION
  • 2012-06. Emerging concepts in haematopoietic cell transplantation in NATURE REVIEWS IMMUNOLOGY
  • 2011-04. Human but not murine multipotent mesenchymal stromal cells exhibit broad-spectrum antimicrobial effector function mediated by indoleamine 2,3-dioxygenase in LEUKEMIA
  • 2000-05. CD34: To select or not to select? That is the question in LEUKEMIA
  • 2009-03. Transplantation of ex-vivo culture-expanded parental haploidentical mesenchymal stem cells to promote engraftment in pediatric recipients of unrelated donor umbilical cord blood: results of a phase I–II clinical trial in BONE MARROW TRANSPLANTATION
  • 2009-01. Reply to ‘The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rates in hematologic malignancy patients: outcome of a pilot clinical study’ by Ning et al. in LEUKEMIA
  • 2007-12. Acute graft versus host disease in ORPHANET JOURNAL OF RARE DISEASES
  • 2008-03. The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical study in LEUKEMIA
  • 2008-01. Lymphocyte subsets recovery following allogeneic bone marrow transplantation (BMT): CD4+ cell count and transplant-related mortality in BONE MARROW TRANSPLANTATION
  • 2001-05. Hepatic graft-versus-host disease presenting as an acute hepatitis after allogeneic peripheral blood stem cell transplantation in BONE MARROW TRANSPLANTATION
  • 2012-04. New strategies for haploidentical transplantation in PEDIATRIC RESEARCH
  • 2011-12. Immunomodulative Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells Cultured in Human Platelet Lysate in JOURNAL OF CLINICAL IMMUNOLOGY
  • 2008-06. Reduced-intensity conditioning in children: a reappraisal in 2008 in BONE MARROW TRANSPLANTATION
  • 2008-01. Acute graft-versus-host disease in children in BONE MARROW TRANSPLANTATION
  • 2010-12. Mesenchymal stem cell as salvage treatment for refractory chronic GVHD in BONE MARROW TRANSPLANTATION
  • Book

    TITLE

    Mesenchymal Stem Cells - Basics and Clinical Application II

    ISBN

    978-3-642-37943-7
    978-3-642-37944-4

    Author Affiliations

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1007/10_2012_158

    DOI

    http://dx.doi.org/10.1007/10_2012_158

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1009681974

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/23455489


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Immunology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Papewalis", 
            "givenName": "Claudia", 
            "id": "sg:person.01277275444.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277275444.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Topolar", 
            "givenName": "Daniela", 
            "id": "sg:person.01024741743.80", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024741743.80"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "G\u00f6tz", 
            "givenName": "Barbara", 
            "id": "sg:person.01023042676.69", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023042676.69"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sch\u00f6nberger", 
            "givenName": "Stefan", 
            "id": "sg:person.01160516562.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160516562.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Hospital Cologne", 
              "id": "https://www.grid.ac/institutes/grid.411097.a", 
              "name": [
                "Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dilloo", 
            "givenName": "Dagmar", 
            "id": "sg:person.01151636031.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151636031.48"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/j.bbmt.2009.11.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000007792"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood.v100.2.406", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000419242"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.immunol.25.022106.141606", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000507551"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1196/annals.1392.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000911052"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2009.254", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001085030", 
              "https://doi.org/10.1038/bmt.2009.254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/096368910x508762", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001466272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/096368910x508762", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001466272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2010.12.055", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003686842"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-04-1559", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003739820"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bmt.1705922", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004003141", 
              "https://doi.org/10.1038/sj.bmt.1705922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/14653240500319234", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004050442"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bcmd.2007.06.021", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004676600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood.v98.2.390", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006718623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1542/peds.2011-2091", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006948193"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2010.03.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007097928"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.01.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007115152"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.09.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008226664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.09.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008226664"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2006-05-024042", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008254358"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0268-960x(95)90031-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008340979"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pmed.0040008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008376851"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2009-12-258442", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008454556"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2011-07-338822", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008930605"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2008.48", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009138012", 
              "https://doi.org/10.1038/bmt.2008.48"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2008.48", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009138012", 
              "https://doi.org/10.1038/bmt.2008.48"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-08-3032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009661208"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.leukres.2011.10.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010781050"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3324/haematol.2009.006171", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010849602"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0301-472x(00)00677-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012870445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri3226", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012946337", 
              "https://doi.org/10.1038/nri3226"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2008-02-138867", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013497861"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.02.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013601730"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci119606", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013734251"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2004.10.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014545298"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/1750-1172-2-35", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014651869", 
              "https://doi.org/10.1186/1750-1172-2-35"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2003-11-3909", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014718402"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2007-10-119370", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014819105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(09)60237-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015034888"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/pr.2011.60", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015255047", 
              "https://doi.org/10.1038/pr.2011.60"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.11.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015292796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.2007-0054", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015792278"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007890-197410000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017240382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007890-197410000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017240382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007890-197410000-00001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017240382"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ajh.20932", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018051174"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2009.03.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018192053"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/14653249.2011.623691", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018602695"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2007.04.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019735071"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1751-553x.2007.00997.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020969795"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2005.09.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021805993"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/096368910x546553", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022382913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3727/096368910x546553", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022382913"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2009.12.056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022441349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.beha.2006.09.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022575915"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.blre.2005.11.002", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022936315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1634/stemcells.19-3-180", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023231597"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cyto.2010.12.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023607463"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2007-02-074997", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024704200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.201141542", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024850113"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/14653240600855905", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025538709"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/14653240902807018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025695557"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2010-02-270777", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026488755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1582-4934.2008.00542.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026623445"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2002-07-2104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027142112"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/leu.2010.310", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027386114", 
              "https://doi.org/10.1038/leu.2010.310"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10875-011-9581-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028027292", 
              "https://doi.org/10.1007/s10875-011-9581-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s10875-011-9581-z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028027292", 
              "https://doi.org/10.1007/s10875-011-9581-z"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/14651858.cd005565.pub2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028317174"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1155/2012/975871", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029631872"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/eji.200738129", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029791574"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1125", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030637450", 
              "https://doi.org/10.1038/nrc1125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc1125", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030637450", 
              "https://doi.org/10.1038/nrc1125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/j.seminhematol.2009.10.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030898257"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2010.04.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031449054"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-08-3036", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031480434"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3324/haematol.11240", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032338418"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2012.06.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032971855"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/14653240903051533", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033217090"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2011-11-354563", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033961331"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.183.6.2645", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034308865"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1751-553x.2009.01181.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034426144"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1751-553x.2009.01181.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034426144"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2005.05614.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034954967"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2005.05614.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034954967"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2005-07-2775", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035413381"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/187152812800392689", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036124737"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2007-04-087056", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038406533"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-03-0803", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038802174"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa022060", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039714315"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2004-11-4557", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039746007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2005-09-3907", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039890086"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2010.04.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040722807"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/14653249.2011.635853", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041836481"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.2010.491", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041887904"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.284.5411.143", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042379237"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2011.05.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042706123"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2141.2012.09114.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042980985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3324/haematol.2010.038356", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043816529"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bmt.1702997", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044233986", 
              "https://doi.org/10.1038/sj.bmt.1702997"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/leu.2008.150", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044407670", 
              "https://doi.org/10.1038/leu.2008.150"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2010.01.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045232453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.beha.2008.03.001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045243013"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bmt.1705870", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045259163", 
              "https://doi.org/10.1038/sj.bmt.1705870"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1053/bbmt.2003.50003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046127027"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s12185-011-0991-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046191149", 
              "https://doi.org/10.1007/s12185-011-0991-8"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.placenta.2011.04.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046721012"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/14653240903502712", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046854250"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-3083.2010.02491.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046980506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-3083.2010.02491.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046980506"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.183.2.657", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048749749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2005-08-3445", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049048845"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2008.348", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049054543", 
              "https://doi.org/10.1038/bmt.2008.348"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.bmt.1705885", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049330215", 
              "https://doi.org/10.1038/sj.bmt.1705885"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/bmt.2010.195", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049896634", 
              "https://doi.org/10.1038/bmt.2010.195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcp.20911", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050221985"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/stem.269", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050387376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2401781", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051350546", 
              "https://doi.org/10.1038/sj.leu.2401781"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2401781", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051350546", 
              "https://doi.org/10.1038/sj.leu.2401781"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2010-12-323824", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051532549"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2008.03.012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051584797"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.tp.0000214462.63943.14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052009886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.tp.0000214462.63943.14", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052009886"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3324/haematol.2011.059378", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052128969"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbmt.2009.12.057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052510467"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/sj.leu.2405090", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053065147", 
              "https://doi.org/10.1038/sj.leu.2405090"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1182/blood-2011-08-339465", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053096770"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1055/s-2004-832357", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057437575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/152581600750062264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059213146"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/scd.2009.0029", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059309963"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/scd.2009.0418", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059310086"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/scd.2010.0447", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059310275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.285.5426.412", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062565968"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1160/th09-04-0250", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063292071"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0022034509340867", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063628678"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/0022034509340867", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063628678"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/138920007780362518", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069175619"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/156652412799218903", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069186226"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/187152809788462635", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069222624"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.4252/wjsc.v2.i4.67", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1072402190"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2013", 
        "datePublishedReg": "2013-01-01", 
        "description": "Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option in hematopoietic disorders, immunodeficiencies and leukemia. To date graft-versus-host disease (GvHD) represents a life-threatening complication even if associated with beneficial antileukemic reactivity. GvHD is the clinical manifestation of donor cells reacting against host tissue. Because of their ability to facilitate endogenous repair and to attenuate inflammation, MSC have evolved as a highly attractive cellular therapeutic in allo-HSCT. Here we report on the clinical experience in the use of MSC to enhance engraftment and prevent and treat acute and chronic GvHD. In early clinical trials, MSC have shown considerable benefit in the setting of manifest GvHD. These encouraging results warrant further exploration. ", 
        "editor": [
          {
            "familyName": "Weyand", 
            "givenName": "Birgit", 
            "type": "Person"
          }, 
          {
            "familyName": "Dominici", 
            "givenName": "Massimo", 
            "type": "Person"
          }, 
          {
            "familyName": "Hass", 
            "givenName": "Ralf", 
            "type": "Person"
          }, 
          {
            "familyName": "Jacobs", 
            "givenName": "Roland", 
            "type": "Person"
          }, 
          {
            "familyName": "Kasper", 
            "givenName": "Cornelia", 
            "type": "Person"
          }
        ], 
        "genre": "chapter", 
        "id": "sg:pub.10.1007/10_2012_158", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isPartOf": {
          "isbn": [
            "978-3-642-37943-7", 
            "978-3-642-37944-4"
          ], 
          "name": "Mesenchymal Stem Cells - Basics and Clinical Application II", 
          "type": "Book"
        }, 
        "name": "Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation", 
        "pagination": "131-62", 
        "productId": [
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1007/10_2012_158"
            ]
          }, 
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "2e1f9115620b54e29bbe3fcd774459c8d62709ece9b305adac25f25d80552c80"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1009681974"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "23455489"
            ]
          }
        ], 
        "publisher": {
          "location": "Berlin, Heidelberg", 
          "name": "Springer Berlin Heidelberg", 
          "type": "Organisation"
        }, 
        "sameAs": [
          "https://doi.org/10.1007/10_2012_158", 
          "https://app.dimensions.ai/details/publication/pub.1009681974"
        ], 
        "sdDataset": "chapters", 
        "sdDatePublished": "2019-04-15T13:41", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8664_00000384.jsonl", 
        "type": "Chapter", 
        "url": "http://link.springer.com/10.1007/10_2012_158"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1007/10_2012_158'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1007/10_2012_158'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1007/10_2012_158'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1007/10_2012_158'


     

    This table displays all metadata directly associated to this object as RDF triples.

    510 TRIPLES      23 PREDICATES      153 URIs      21 LITERALS      9 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1007/10_2012_158 schema:about anzsrc-for:11
    2 anzsrc-for:1107
    3 schema:author Nddcfa2d6045d440cb9d27044bc537ebd
    4 schema:citation sg:pub.10.1007/s10875-011-9581-z
    5 sg:pub.10.1007/s12185-011-0991-8
    6 sg:pub.10.1038/bmt.2008.348
    7 sg:pub.10.1038/bmt.2008.48
    8 sg:pub.10.1038/bmt.2009.254
    9 sg:pub.10.1038/bmt.2010.195
    10 sg:pub.10.1038/leu.2008.150
    11 sg:pub.10.1038/leu.2010.310
    12 sg:pub.10.1038/nrc1125
    13 sg:pub.10.1038/nri3226
    14 sg:pub.10.1038/pr.2011.60
    15 sg:pub.10.1038/sj.bmt.1702997
    16 sg:pub.10.1038/sj.bmt.1705870
    17 sg:pub.10.1038/sj.bmt.1705885
    18 sg:pub.10.1038/sj.bmt.1705922
    19 sg:pub.10.1038/sj.leu.2401781
    20 sg:pub.10.1038/sj.leu.2405090
    21 sg:pub.10.1186/1750-1172-2-35
    22 https://doi.org/10.1001/jama.2010.491
    23 https://doi.org/10.1002/14651858.cd005565.pub2
    24 https://doi.org/10.1002/ajh.20932
    25 https://doi.org/10.1002/eji.200738129
    26 https://doi.org/10.1002/eji.201141542
    27 https://doi.org/10.1002/jcp.20911
    28 https://doi.org/10.1002/stem.269
    29 https://doi.org/10.1016/j.bbmt.2004.10.004
    30 https://doi.org/10.1016/j.bbmt.2005.01.011
    31 https://doi.org/10.1016/j.bbmt.2005.02.001
    32 https://doi.org/10.1016/j.bbmt.2005.09.004
    33 https://doi.org/10.1016/j.bbmt.2005.09.012
    34 https://doi.org/10.1016/j.bbmt.2005.11.010
    35 https://doi.org/10.1016/j.bbmt.2007.04.010
    36 https://doi.org/10.1016/j.bbmt.2008.03.012
    37 https://doi.org/10.1016/j.bbmt.2009.03.012
    38 https://doi.org/10.1016/j.bbmt.2009.11.006
    39 https://doi.org/10.1016/j.bbmt.2009.12.056
    40 https://doi.org/10.1016/j.bbmt.2009.12.057
    41 https://doi.org/10.1016/j.bbmt.2010.01.011
    42 https://doi.org/10.1016/j.bbmt.2010.03.017
    43 https://doi.org/10.1016/j.bbmt.2010.04.008
    44 https://doi.org/10.1016/j.bbmt.2010.04.014
    45 https://doi.org/10.1016/j.bbmt.2010.12.055
    46 https://doi.org/10.1016/j.bbmt.2011.05.001
    47 https://doi.org/10.1016/j.bbmt.2012.06.014
    48 https://doi.org/10.1016/j.bcmd.2007.06.021
    49 https://doi.org/10.1016/j.beha.2006.09.001
    50 https://doi.org/10.1016/j.beha.2008.03.001
    51 https://doi.org/10.1016/j.blre.2005.11.002
    52 https://doi.org/10.1016/j.cyto.2010.12.008
    53 https://doi.org/10.1016/j.leukres.2011.10.016
    54 https://doi.org/10.1016/j.placenta.2011.04.013
    55 https://doi.org/10.1016/s0140-6736(09)60237-3
    56 https://doi.org/10.1016/s0268-960x(95)90031-4
    57 https://doi.org/10.1016/s0301-472x(00)00677-9
    58 https://doi.org/10.1053/bbmt.2003.50003
    59 https://doi.org/10.1053/j.seminhematol.2009.10.011
    60 https://doi.org/10.1055/s-2004-832357
    61 https://doi.org/10.1056/nejmoa022060
    62 https://doi.org/10.1080/14653240500319234
    63 https://doi.org/10.1080/14653240600855905
    64 https://doi.org/10.1080/14653240902807018
    65 https://doi.org/10.1080/14653240903051533
    66 https://doi.org/10.1084/jem.183.2.657
    67 https://doi.org/10.1084/jem.183.6.2645
    68 https://doi.org/10.1089/152581600750062264
    69 https://doi.org/10.1089/scd.2009.0029
    70 https://doi.org/10.1089/scd.2009.0418
    71 https://doi.org/10.1089/scd.2010.0447
    72 https://doi.org/10.1097/00007890-197410000-00001
    73 https://doi.org/10.1097/01.tp.0000214462.63943.14
    74 https://doi.org/10.1111/j.1365-2141.2005.05614.x
    75 https://doi.org/10.1111/j.1365-2141.2012.09114.x
    76 https://doi.org/10.1111/j.1365-3083.2010.02491.x
    77 https://doi.org/10.1111/j.1582-4934.2008.00542.x
    78 https://doi.org/10.1111/j.1751-553x.2007.00997.x
    79 https://doi.org/10.1111/j.1751-553x.2009.01181.x
    80 https://doi.org/10.1126/science.284.5411.143
    81 https://doi.org/10.1126/science.285.5426.412
    82 https://doi.org/10.1146/annurev.immunol.25.022106.141606
    83 https://doi.org/10.1155/2012/975871
    84 https://doi.org/10.1160/th09-04-0250
    85 https://doi.org/10.1172/jci119606
    86 https://doi.org/10.1177/0022034509340867
    87 https://doi.org/10.1182/blood-2002-07-2104
    88 https://doi.org/10.1182/blood-2003-11-3909
    89 https://doi.org/10.1182/blood-2004-03-0803
    90 https://doi.org/10.1182/blood-2004-04-1559
    91 https://doi.org/10.1182/blood-2004-08-3032
    92 https://doi.org/10.1182/blood-2004-08-3036
    93 https://doi.org/10.1182/blood-2004-11-4557
    94 https://doi.org/10.1182/blood-2005-07-2775
    95 https://doi.org/10.1182/blood-2005-08-3445
    96 https://doi.org/10.1182/blood-2005-09-3907
    97 https://doi.org/10.1182/blood-2006-05-024042
    98 https://doi.org/10.1182/blood-2007-02-074997
    99 https://doi.org/10.1182/blood-2007-04-087056
    100 https://doi.org/10.1182/blood-2007-10-119370
    101 https://doi.org/10.1182/blood-2008-02-138867
    102 https://doi.org/10.1182/blood-2009-12-258442
    103 https://doi.org/10.1182/blood-2010-02-270777
    104 https://doi.org/10.1182/blood-2010-12-323824
    105 https://doi.org/10.1182/blood-2011-07-338822
    106 https://doi.org/10.1182/blood-2011-08-339465
    107 https://doi.org/10.1182/blood-2011-11-354563
    108 https://doi.org/10.1182/blood.v100.2.406
    109 https://doi.org/10.1182/blood.v98.2.390
    110 https://doi.org/10.1196/annals.1392.022
    111 https://doi.org/10.1371/journal.pmed.0040008
    112 https://doi.org/10.1542/peds.2011-2091
    113 https://doi.org/10.1634/stemcells.19-3-180
    114 https://doi.org/10.1634/stemcells.2007-0054
    115 https://doi.org/10.2174/138920007780362518
    116 https://doi.org/10.2174/156652412799218903
    117 https://doi.org/10.2174/187152809788462635
    118 https://doi.org/10.2174/187152812800392689
    119 https://doi.org/10.3109/14653240903502712
    120 https://doi.org/10.3109/14653249.2011.623691
    121 https://doi.org/10.3109/14653249.2011.635853
    122 https://doi.org/10.3324/haematol.11240
    123 https://doi.org/10.3324/haematol.2009.006171
    124 https://doi.org/10.3324/haematol.2010.038356
    125 https://doi.org/10.3324/haematol.2011.059378
    126 https://doi.org/10.3727/096368910x508762
    127 https://doi.org/10.3727/096368910x546553
    128 https://doi.org/10.4252/wjsc.v2.i4.67
    129 schema:datePublished 2013
    130 schema:datePublishedReg 2013-01-01
    131 schema:description Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment option in hematopoietic disorders, immunodeficiencies and leukemia. To date graft-versus-host disease (GvHD) represents a life-threatening complication even if associated with beneficial antileukemic reactivity. GvHD is the clinical manifestation of donor cells reacting against host tissue. Because of their ability to facilitate endogenous repair and to attenuate inflammation, MSC have evolved as a highly attractive cellular therapeutic in allo-HSCT. Here we report on the clinical experience in the use of MSC to enhance engraftment and prevent and treat acute and chronic GvHD. In early clinical trials, MSC have shown considerable benefit in the setting of manifest GvHD. These encouraging results warrant further exploration.
    132 schema:editor Nfb2e38515ed24effba1b5862b946a6e6
    133 schema:genre chapter
    134 schema:inLanguage en
    135 schema:isAccessibleForFree false
    136 schema:isPartOf N7082c85deb734b3d9b17556e6398adde
    137 schema:name Mesenchymal Stem Cells as Cellular Immunotherapeutics in Allogeneic Hematopoietic Stem Cell Transplantation
    138 schema:pagination 131-62
    139 schema:productId N1a1c4fb2192b436aa12aa2f260e29b5b
    140 N49224e50a42041e0884c9cd5a82d67b1
    141 N779ec2cd376344a7b6d9de668fc9de49
    142 Nb120269351894f87948d60296d6d1032
    143 schema:publisher N1737003f632c4748a419926c071c9027
    144 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009681974
    145 https://doi.org/10.1007/10_2012_158
    146 schema:sdDatePublished 2019-04-15T13:41
    147 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    148 schema:sdPublisher N8483ebaf9b39418a9d17e6c4cdfe7238
    149 schema:url http://link.springer.com/10.1007/10_2012_158
    150 sgo:license sg:explorer/license/
    151 sgo:sdDataset chapters
    152 rdf:type schema:Chapter
    153 N00368cc12da54035b3ba0cfa63a538e2 schema:familyName Dominici
    154 schema:givenName Massimo
    155 rdf:type schema:Person
    156 N039c5cf92796447cb10c655d348b4ce2 schema:familyName Hass
    157 schema:givenName Ralf
    158 rdf:type schema:Person
    159 N1737003f632c4748a419926c071c9027 schema:location Berlin, Heidelberg
    160 schema:name Springer Berlin Heidelberg
    161 rdf:type schema:Organisation
    162 N1a1c4fb2192b436aa12aa2f260e29b5b schema:name readcube_id
    163 schema:value 2e1f9115620b54e29bbe3fcd774459c8d62709ece9b305adac25f25d80552c80
    164 rdf:type schema:PropertyValue
    165 N1a967843c2484db0adf0bfea6d1e847b rdf:first sg:person.01151636031.48
    166 rdf:rest rdf:nil
    167 N49224e50a42041e0884c9cd5a82d67b1 schema:name pubmed_id
    168 schema:value 23455489
    169 rdf:type schema:PropertyValue
    170 N4bff2472618249a2a08e5a9ce4064ca5 rdf:first Nd0d43d1d1a2a4d32a349146e31a0d3bc
    171 rdf:rest Nd2a971947e46432abfc2d4f0c7ca7327
    172 N5130dc841ec543b8999626b708a1b73e rdf:first sg:person.01024741743.80
    173 rdf:rest Na1e5e20549b4407a9f20a972c8c5048d
    174 N56d843041c4a4b1f9c4d9d05c6ae937e rdf:first N00368cc12da54035b3ba0cfa63a538e2
    175 rdf:rest Ne010ff8663c7454fa709ff93048e0e58
    176 N7082c85deb734b3d9b17556e6398adde schema:isbn 978-3-642-37943-7
    177 978-3-642-37944-4
    178 schema:name Mesenchymal Stem Cells - Basics and Clinical Application II
    179 rdf:type schema:Book
    180 N779ec2cd376344a7b6d9de668fc9de49 schema:name doi
    181 schema:value 10.1007/10_2012_158
    182 rdf:type schema:PropertyValue
    183 N8483ebaf9b39418a9d17e6c4cdfe7238 schema:name Springer Nature - SN SciGraph project
    184 rdf:type schema:Organization
    185 Na1e5e20549b4407a9f20a972c8c5048d rdf:first sg:person.01023042676.69
    186 rdf:rest Nab2b31a5c55e4caaaf61d9b9b23c3632
    187 Nab2b31a5c55e4caaaf61d9b9b23c3632 rdf:first sg:person.01160516562.84
    188 rdf:rest N1a967843c2484db0adf0bfea6d1e847b
    189 Nb120269351894f87948d60296d6d1032 schema:name dimensions_id
    190 schema:value pub.1009681974
    191 rdf:type schema:PropertyValue
    192 Nb465fdc61f5c45f28232a8a8508c23ea schema:familyName Weyand
    193 schema:givenName Birgit
    194 rdf:type schema:Person
    195 Nb5b1760522e44dbc8c0b29f05739cb96 schema:familyName Kasper
    196 schema:givenName Cornelia
    197 rdf:type schema:Person
    198 Nd0d43d1d1a2a4d32a349146e31a0d3bc schema:familyName Jacobs
    199 schema:givenName Roland
    200 rdf:type schema:Person
    201 Nd2a971947e46432abfc2d4f0c7ca7327 rdf:first Nb5b1760522e44dbc8c0b29f05739cb96
    202 rdf:rest rdf:nil
    203 Nddcfa2d6045d440cb9d27044bc537ebd rdf:first sg:person.01277275444.75
    204 rdf:rest N5130dc841ec543b8999626b708a1b73e
    205 Ne010ff8663c7454fa709ff93048e0e58 rdf:first N039c5cf92796447cb10c655d348b4ce2
    206 rdf:rest N4bff2472618249a2a08e5a9ce4064ca5
    207 Nfb2e38515ed24effba1b5862b946a6e6 rdf:first Nb465fdc61f5c45f28232a8a8508c23ea
    208 rdf:rest N56d843041c4a4b1f9c4d9d05c6ae937e
    209 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    210 schema:name Medical and Health Sciences
    211 rdf:type schema:DefinedTerm
    212 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
    213 schema:name Immunology
    214 rdf:type schema:DefinedTerm
    215 sg:person.01023042676.69 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    216 schema:familyName Götz
    217 schema:givenName Barbara
    218 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023042676.69
    219 rdf:type schema:Person
    220 sg:person.01024741743.80 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    221 schema:familyName Topolar
    222 schema:givenName Daniela
    223 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01024741743.80
    224 rdf:type schema:Person
    225 sg:person.01151636031.48 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    226 schema:familyName Dilloo
    227 schema:givenName Dagmar
    228 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01151636031.48
    229 rdf:type schema:Person
    230 sg:person.01160516562.84 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    231 schema:familyName Schönberger
    232 schema:givenName Stefan
    233 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01160516562.84
    234 rdf:type schema:Person
    235 sg:person.01277275444.75 schema:affiliation https://www.grid.ac/institutes/grid.411097.a
    236 schema:familyName Papewalis
    237 schema:givenName Claudia
    238 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01277275444.75
    239 rdf:type schema:Person
    240 sg:pub.10.1007/s10875-011-9581-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1028027292
    241 https://doi.org/10.1007/s10875-011-9581-z
    242 rdf:type schema:CreativeWork
    243 sg:pub.10.1007/s12185-011-0991-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046191149
    244 https://doi.org/10.1007/s12185-011-0991-8
    245 rdf:type schema:CreativeWork
    246 sg:pub.10.1038/bmt.2008.348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049054543
    247 https://doi.org/10.1038/bmt.2008.348
    248 rdf:type schema:CreativeWork
    249 sg:pub.10.1038/bmt.2008.48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009138012
    250 https://doi.org/10.1038/bmt.2008.48
    251 rdf:type schema:CreativeWork
    252 sg:pub.10.1038/bmt.2009.254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001085030
    253 https://doi.org/10.1038/bmt.2009.254
    254 rdf:type schema:CreativeWork
    255 sg:pub.10.1038/bmt.2010.195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049896634
    256 https://doi.org/10.1038/bmt.2010.195
    257 rdf:type schema:CreativeWork
    258 sg:pub.10.1038/leu.2008.150 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044407670
    259 https://doi.org/10.1038/leu.2008.150
    260 rdf:type schema:CreativeWork
    261 sg:pub.10.1038/leu.2010.310 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027386114
    262 https://doi.org/10.1038/leu.2010.310
    263 rdf:type schema:CreativeWork
    264 sg:pub.10.1038/nrc1125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030637450
    265 https://doi.org/10.1038/nrc1125
    266 rdf:type schema:CreativeWork
    267 sg:pub.10.1038/nri3226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012946337
    268 https://doi.org/10.1038/nri3226
    269 rdf:type schema:CreativeWork
    270 sg:pub.10.1038/pr.2011.60 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015255047
    271 https://doi.org/10.1038/pr.2011.60
    272 rdf:type schema:CreativeWork
    273 sg:pub.10.1038/sj.bmt.1702997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044233986
    274 https://doi.org/10.1038/sj.bmt.1702997
    275 rdf:type schema:CreativeWork
    276 sg:pub.10.1038/sj.bmt.1705870 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045259163
    277 https://doi.org/10.1038/sj.bmt.1705870
    278 rdf:type schema:CreativeWork
    279 sg:pub.10.1038/sj.bmt.1705885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049330215
    280 https://doi.org/10.1038/sj.bmt.1705885
    281 rdf:type schema:CreativeWork
    282 sg:pub.10.1038/sj.bmt.1705922 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004003141
    283 https://doi.org/10.1038/sj.bmt.1705922
    284 rdf:type schema:CreativeWork
    285 sg:pub.10.1038/sj.leu.2401781 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051350546
    286 https://doi.org/10.1038/sj.leu.2401781
    287 rdf:type schema:CreativeWork
    288 sg:pub.10.1038/sj.leu.2405090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053065147
    289 https://doi.org/10.1038/sj.leu.2405090
    290 rdf:type schema:CreativeWork
    291 sg:pub.10.1186/1750-1172-2-35 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014651869
    292 https://doi.org/10.1186/1750-1172-2-35
    293 rdf:type schema:CreativeWork
    294 https://doi.org/10.1001/jama.2010.491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041887904
    295 rdf:type schema:CreativeWork
    296 https://doi.org/10.1002/14651858.cd005565.pub2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028317174
    297 rdf:type schema:CreativeWork
    298 https://doi.org/10.1002/ajh.20932 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018051174
    299 rdf:type schema:CreativeWork
    300 https://doi.org/10.1002/eji.200738129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029791574
    301 rdf:type schema:CreativeWork
    302 https://doi.org/10.1002/eji.201141542 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024850113
    303 rdf:type schema:CreativeWork
    304 https://doi.org/10.1002/jcp.20911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050221985
    305 rdf:type schema:CreativeWork
    306 https://doi.org/10.1002/stem.269 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050387376
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1016/j.bbmt.2004.10.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014545298
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1016/j.bbmt.2005.01.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007115152
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1016/j.bbmt.2005.02.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013601730
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1016/j.bbmt.2005.09.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008226664
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1016/j.bbmt.2005.09.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021805993
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1016/j.bbmt.2005.11.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015292796
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1016/j.bbmt.2007.04.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019735071
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1016/j.bbmt.2008.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051584797
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1016/j.bbmt.2009.03.012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018192053
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1016/j.bbmt.2009.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000007792
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.1016/j.bbmt.2009.12.056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022441349
    329 rdf:type schema:CreativeWork
    330 https://doi.org/10.1016/j.bbmt.2009.12.057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052510467
    331 rdf:type schema:CreativeWork
    332 https://doi.org/10.1016/j.bbmt.2010.01.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045232453
    333 rdf:type schema:CreativeWork
    334 https://doi.org/10.1016/j.bbmt.2010.03.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007097928
    335 rdf:type schema:CreativeWork
    336 https://doi.org/10.1016/j.bbmt.2010.04.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031449054
    337 rdf:type schema:CreativeWork
    338 https://doi.org/10.1016/j.bbmt.2010.04.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040722807
    339 rdf:type schema:CreativeWork
    340 https://doi.org/10.1016/j.bbmt.2010.12.055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003686842
    341 rdf:type schema:CreativeWork
    342 https://doi.org/10.1016/j.bbmt.2011.05.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042706123
    343 rdf:type schema:CreativeWork
    344 https://doi.org/10.1016/j.bbmt.2012.06.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032971855
    345 rdf:type schema:CreativeWork
    346 https://doi.org/10.1016/j.bcmd.2007.06.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004676600
    347 rdf:type schema:CreativeWork
    348 https://doi.org/10.1016/j.beha.2006.09.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022575915
    349 rdf:type schema:CreativeWork
    350 https://doi.org/10.1016/j.beha.2008.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045243013
    351 rdf:type schema:CreativeWork
    352 https://doi.org/10.1016/j.blre.2005.11.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022936315
    353 rdf:type schema:CreativeWork
    354 https://doi.org/10.1016/j.cyto.2010.12.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023607463
    355 rdf:type schema:CreativeWork
    356 https://doi.org/10.1016/j.leukres.2011.10.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010781050
    357 rdf:type schema:CreativeWork
    358 https://doi.org/10.1016/j.placenta.2011.04.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046721012
    359 rdf:type schema:CreativeWork
    360 https://doi.org/10.1016/s0140-6736(09)60237-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015034888
    361 rdf:type schema:CreativeWork
    362 https://doi.org/10.1016/s0268-960x(95)90031-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008340979
    363 rdf:type schema:CreativeWork
    364 https://doi.org/10.1016/s0301-472x(00)00677-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012870445
    365 rdf:type schema:CreativeWork
    366 https://doi.org/10.1053/bbmt.2003.50003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046127027
    367 rdf:type schema:CreativeWork
    368 https://doi.org/10.1053/j.seminhematol.2009.10.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030898257
    369 rdf:type schema:CreativeWork
    370 https://doi.org/10.1055/s-2004-832357 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057437575
    371 rdf:type schema:CreativeWork
    372 https://doi.org/10.1056/nejmoa022060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039714315
    373 rdf:type schema:CreativeWork
    374 https://doi.org/10.1080/14653240500319234 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004050442
    375 rdf:type schema:CreativeWork
    376 https://doi.org/10.1080/14653240600855905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025538709
    377 rdf:type schema:CreativeWork
    378 https://doi.org/10.1080/14653240902807018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025695557
    379 rdf:type schema:CreativeWork
    380 https://doi.org/10.1080/14653240903051533 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033217090
    381 rdf:type schema:CreativeWork
    382 https://doi.org/10.1084/jem.183.2.657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048749749
    383 rdf:type schema:CreativeWork
    384 https://doi.org/10.1084/jem.183.6.2645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034308865
    385 rdf:type schema:CreativeWork
    386 https://doi.org/10.1089/152581600750062264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059213146
    387 rdf:type schema:CreativeWork
    388 https://doi.org/10.1089/scd.2009.0029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059309963
    389 rdf:type schema:CreativeWork
    390 https://doi.org/10.1089/scd.2009.0418 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059310086
    391 rdf:type schema:CreativeWork
    392 https://doi.org/10.1089/scd.2010.0447 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059310275
    393 rdf:type schema:CreativeWork
    394 https://doi.org/10.1097/00007890-197410000-00001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017240382
    395 rdf:type schema:CreativeWork
    396 https://doi.org/10.1097/01.tp.0000214462.63943.14 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052009886
    397 rdf:type schema:CreativeWork
    398 https://doi.org/10.1111/j.1365-2141.2005.05614.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034954967
    399 rdf:type schema:CreativeWork
    400 https://doi.org/10.1111/j.1365-2141.2012.09114.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1042980985
    401 rdf:type schema:CreativeWork
    402 https://doi.org/10.1111/j.1365-3083.2010.02491.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046980506
    403 rdf:type schema:CreativeWork
    404 https://doi.org/10.1111/j.1582-4934.2008.00542.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026623445
    405 rdf:type schema:CreativeWork
    406 https://doi.org/10.1111/j.1751-553x.2007.00997.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020969795
    407 rdf:type schema:CreativeWork
    408 https://doi.org/10.1111/j.1751-553x.2009.01181.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1034426144
    409 rdf:type schema:CreativeWork
    410 https://doi.org/10.1126/science.284.5411.143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042379237
    411 rdf:type schema:CreativeWork
    412 https://doi.org/10.1126/science.285.5426.412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062565968
    413 rdf:type schema:CreativeWork
    414 https://doi.org/10.1146/annurev.immunol.25.022106.141606 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000507551
    415 rdf:type schema:CreativeWork
    416 https://doi.org/10.1155/2012/975871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029631872
    417 rdf:type schema:CreativeWork
    418 https://doi.org/10.1160/th09-04-0250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063292071
    419 rdf:type schema:CreativeWork
    420 https://doi.org/10.1172/jci119606 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013734251
    421 rdf:type schema:CreativeWork
    422 https://doi.org/10.1177/0022034509340867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063628678
    423 rdf:type schema:CreativeWork
    424 https://doi.org/10.1182/blood-2002-07-2104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027142112
    425 rdf:type schema:CreativeWork
    426 https://doi.org/10.1182/blood-2003-11-3909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014718402
    427 rdf:type schema:CreativeWork
    428 https://doi.org/10.1182/blood-2004-03-0803 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038802174
    429 rdf:type schema:CreativeWork
    430 https://doi.org/10.1182/blood-2004-04-1559 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003739820
    431 rdf:type schema:CreativeWork
    432 https://doi.org/10.1182/blood-2004-08-3032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009661208
    433 rdf:type schema:CreativeWork
    434 https://doi.org/10.1182/blood-2004-08-3036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031480434
    435 rdf:type schema:CreativeWork
    436 https://doi.org/10.1182/blood-2004-11-4557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039746007
    437 rdf:type schema:CreativeWork
    438 https://doi.org/10.1182/blood-2005-07-2775 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035413381
    439 rdf:type schema:CreativeWork
    440 https://doi.org/10.1182/blood-2005-08-3445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049048845
    441 rdf:type schema:CreativeWork
    442 https://doi.org/10.1182/blood-2005-09-3907 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039890086
    443 rdf:type schema:CreativeWork
    444 https://doi.org/10.1182/blood-2006-05-024042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008254358
    445 rdf:type schema:CreativeWork
    446 https://doi.org/10.1182/blood-2007-02-074997 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024704200
    447 rdf:type schema:CreativeWork
    448 https://doi.org/10.1182/blood-2007-04-087056 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038406533
    449 rdf:type schema:CreativeWork
    450 https://doi.org/10.1182/blood-2007-10-119370 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014819105
    451 rdf:type schema:CreativeWork
    452 https://doi.org/10.1182/blood-2008-02-138867 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013497861
    453 rdf:type schema:CreativeWork
    454 https://doi.org/10.1182/blood-2009-12-258442 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008454556
    455 rdf:type schema:CreativeWork
    456 https://doi.org/10.1182/blood-2010-02-270777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026488755
    457 rdf:type schema:CreativeWork
    458 https://doi.org/10.1182/blood-2010-12-323824 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051532549
    459 rdf:type schema:CreativeWork
    460 https://doi.org/10.1182/blood-2011-07-338822 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008930605
    461 rdf:type schema:CreativeWork
    462 https://doi.org/10.1182/blood-2011-08-339465 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053096770
    463 rdf:type schema:CreativeWork
    464 https://doi.org/10.1182/blood-2011-11-354563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033961331
    465 rdf:type schema:CreativeWork
    466 https://doi.org/10.1182/blood.v100.2.406 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000419242
    467 rdf:type schema:CreativeWork
    468 https://doi.org/10.1182/blood.v98.2.390 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006718623
    469 rdf:type schema:CreativeWork
    470 https://doi.org/10.1196/annals.1392.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000911052
    471 rdf:type schema:CreativeWork
    472 https://doi.org/10.1371/journal.pmed.0040008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008376851
    473 rdf:type schema:CreativeWork
    474 https://doi.org/10.1542/peds.2011-2091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006948193
    475 rdf:type schema:CreativeWork
    476 https://doi.org/10.1634/stemcells.19-3-180 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023231597
    477 rdf:type schema:CreativeWork
    478 https://doi.org/10.1634/stemcells.2007-0054 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015792278
    479 rdf:type schema:CreativeWork
    480 https://doi.org/10.2174/138920007780362518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069175619
    481 rdf:type schema:CreativeWork
    482 https://doi.org/10.2174/156652412799218903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069186226
    483 rdf:type schema:CreativeWork
    484 https://doi.org/10.2174/187152809788462635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069222624
    485 rdf:type schema:CreativeWork
    486 https://doi.org/10.2174/187152812800392689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036124737
    487 rdf:type schema:CreativeWork
    488 https://doi.org/10.3109/14653240903502712 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046854250
    489 rdf:type schema:CreativeWork
    490 https://doi.org/10.3109/14653249.2011.623691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018602695
    491 rdf:type schema:CreativeWork
    492 https://doi.org/10.3109/14653249.2011.635853 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041836481
    493 rdf:type schema:CreativeWork
    494 https://doi.org/10.3324/haematol.11240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032338418
    495 rdf:type schema:CreativeWork
    496 https://doi.org/10.3324/haematol.2009.006171 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010849602
    497 rdf:type schema:CreativeWork
    498 https://doi.org/10.3324/haematol.2010.038356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043816529
    499 rdf:type schema:CreativeWork
    500 https://doi.org/10.3324/haematol.2011.059378 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052128969
    501 rdf:type schema:CreativeWork
    502 https://doi.org/10.3727/096368910x508762 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001466272
    503 rdf:type schema:CreativeWork
    504 https://doi.org/10.3727/096368910x546553 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022382913
    505 rdf:type schema:CreativeWork
    506 https://doi.org/10.4252/wjsc.v2.i4.67 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072402190
    507 rdf:type schema:CreativeWork
    508 https://www.grid.ac/institutes/grid.411097.a schema:alternateName University Hospital Cologne
    509 schema:name Department of Pediatric Hematology and Oncology, Center for Pediatrics, University Hospital, Friedrich-Wilhelm University, Bonn, Germany
    510 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...