Ontology type: schema:Chapter
2004
AUTHORSMuriel Thoby-Brisson , Sandra Autran , Gilles Fortin , Jean Champagnat
ABSTRACTNeurotrophins are a class of factors known to be involved in the development, maintenance, plasticity and survival of the peripheral and central nervous systems1. Neurotrophins are active through high-affinity receptors having an intrinsic tyrosine-kinase activity2,3. One of these neurotrophins, the brain-derived neurotrophic factor (BDNF) has been shown to be involved in a wide range of developmental and plasticity mechanisms and its biological action depends mainly upon activation of the TrkB receptor sub-type and to a less extent to the p75 receptors. BDNF binding on TrkB receptors initiates a cascade of events of phosphorylation that activate a complex of signal proteins and the induction of several genes4. More... »
PAGES115-120
Post-Genomic Perspectives in Modeling and Control of Breathing
ISBN
978-0-306-48507-7
978-0-387-27023-4
http://scigraph.springernature.com/pub.10.1007/0-387-27023-x_18
DOIhttp://dx.doi.org/10.1007/0-387-27023-x_18
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1002283117
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15602952
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