Iduna Fichtner

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Publications in SciGraph latest 50 shown

  • 2018-12 Loss-of-function uORF mutations in human malignancies in SCIENTIFIC REPORTS
  • 2018-12 Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance in GENOME MEDICINE
  • 2018-05 Treatment with 5-azacitidine delay growth of glioblastoma xenografts: a potential new treatment approach for glioblastomas in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2017-07-11 Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative in BRITISH JOURNAL OF CANCER
  • 2016-11 SPON2, a newly identified target gene of MACC1, drives colorectal cancer metastasis in mice and is prognostic for colorectal cancer patient survival in ONCOGENE
  • 2016-08 Preclinical Study of a Combination of Erlotinib and Bevacizumab in Early Stages of Unselected Non-Small Cell Lung Cancer Patient-Derived Xenografts in TARGETED ONCOLOGY
  • 2015-02 Cell differentiation mediated by co-culture of human umbilical cord blood stem cells with murine hepatic cells in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL
  • 2015-02 Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo in ONCOGENESIS
  • 2012-08 Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model in INVESTIGATIONAL NEW DRUGS
  • 2012-08 Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice. in INVESTIGATIONAL NEW DRUGS
  • 2012-07 Treatment of Experimental Brain Metastasis with MTO-Liposomes: Impact of Fluidity and LRP-Targeting on the Therapeutic Result in PHARMACEUTICAL RESEARCH
  • 2012-05 Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors in GENE THERAPY
  • 2012-03 Transcriptional expression profile of cultured human embryonic stem cells in vitro and in vivo in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL
  • 2011-06 Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models in INVESTIGATIONAL NEW DRUGS
  • 2011-04 Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2′-deoxyuridine in INVESTIGATIONAL NEW DRUGS
  • 2010-10 Activation of the CMV-IE Promoter by Hyperthermia In Vitro and In Vivo: Biphasic Heat Induction of Cytosine Deaminase Suicide Gene Expression in MOLECULAR BIOTECHNOLOGY
  • 2010-05 Inhibition of pulmonary metastasis in a human MT3 breast cancer xenograft model by dual liposomes preventing intravasal fibrin clot formation in BREAST CANCER RESEARCH AND TREATMENT
  • 2010-02 INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model in INVESTIGATIONAL NEW DRUGS
  • 2010-01 Inhibition of metastasis in a murine 4T1 breast cancer model by liposomes preventing tumor cell-platelet interactions in CLINICAL & EXPERIMENTAL METASTASIS
  • 2009-07 In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2009-03 Radiosensitisation of U87MG brain tumours by anti-epidermal growth factor receptor monoclonal antibodies in BRITISH JOURNAL OF CANCER
  • 2009 Nonviral Jet-Injection Technology for Intratumoral In Vivo Gene Transfer of Naked DNA in GENE THERAPY OF CANCER
  • 2009-01 MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis in NATURE MEDICINE
  • 2007-11 Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo in BRITISH JOURNAL OF CANCER
  • 2007-08 Enhanced tumorigenicity of fibroblasts transformed with human herpesvirus 8 chemokine receptor vGPCR by successive passage in nude and immunocompetent mice in ONCOGENE
  • 2007-07 The mTOR pathway inhibitor RAD001 (everolimus) is highly efficacious in tamoxifen-sensitive and -resistant breast cancer xenografts in TARGETED ONCOLOGY
  • 2006-08 Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia in LEUKEMIA
  • 2006-07 Potent inhibition of local and disseminated tumor growth in immunocompetent mouse models by a bispecific antibody construct specific for Murine CD3 in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2004-10 Liposomal 4-hydroxy-tamoxifen: effect on cellular uptake and resulting cytotoxicity in drug resistant breast cancer cells in vitro in BREAST CANCER RESEARCH AND TREATMENT
  • 2004-10 Low-volume jet injection for efficient nonviral in vivo gene transfer in MOLECULAR BIOTECHNOLOGY
  • 2004-09 The Experimental Antitumor Agents Phortress and Doxorubicin are Equiactive Against Human-Derived Breast Carcinoma Xenograft Models in BREAST CANCER RESEARCH AND TREATMENT
  • 2003-04 Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy in CANCER GENE THERAPY
  • 2002-11 Sensitive PCR method for the detection and real-time quantification of human cells in xenotransplantation systems in BRITISH JOURNAL OF CANCER
  • 2002-06 Intratumoral low-volume jet-injection for efficient nonviral gene transfer in MOLECULAR BIOTECHNOLOGY
  • 2001-11 Influence of Surface-Modifying Surfactants on the Pharmacokinetic Behavior of 14C-Poly (Methylmethacrylate) Nanoparticles in Experimental Tumor Models in PHARMACEUTICAL RESEARCH
  • 2001-02 Nonviral in vivo gene delivery into tumors using a novel low volume jet-injection technology in GENE THERAPY
  • 2001 In vivo Gentransfer nackter DNA in xenotransplantierte Kolonkarzinome in der Nude Maus mit Hilfe der Jet-Injektion in CHIRURGISCHES FORUM 2001 FÜR EXPERIMENTELLE UND KLINISCHE FORSCHUNG
  • 2000-06 mdr1 promoter-driven tumor necrosis factor-α expression for a chemotherapy-controllable combined in vivo gene therapy and chemotherapy of tumors in CANCER GENE THERAPY
  • 2000-05 Cytotoxicity, cell-cycle perturbations and apoptosis in human tumor cells by lipophilic N4-alkyl-1-β-D-arabinofuranosylcytosine derivatives and the new heteronucleoside phosphate dimer arabinocytidylyl-(5′→ 5′)-N4-octadecyl-1-β-d-arabinofuranosylcytosine in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2000-03 Differences in immunoreactivity of estrogen receptor (ER) in tamoxifen-sensitive and -resistant breast carcinomas: preclinical and first clinical investigations in BREAST CANCER RESEARCH AND TREATMENT
  • 2000 Development and characterization of a tamoxifen-resistant breast carcinoma xenograft in BRITISH JOURNAL OF CANCER
  • 1999-11 Pharmacokinetics of sterically stabilized hexadecylphosphocholine liposomes versus conventional liposomes and free hexadecylphosphocholine in tumor-free and human breast carcinoma bearing mice in BREAST CANCER RESEARCH AND TREATMENT
  • 1999-03 The chemokine RANTES is secreted by human melanoma cells and is associated with enhanced tumour formation in nude mice in BRITISH JOURNAL OF CANCER
  • 1998 In Vivo Evaluation of a Drug-Inducible Vector System for the Combined Gene-and Chemotherapy of Cancer in GENE THERAPY OF CANCER
  • 1997-05 Antineoplastic activity of sterically stabilized alkylphosphocholine liposomes in human breast carcinomas in BREAST CANCER RESEARCH AND TREATMENT
  • 1996-07 Metastatic potential of human melanoma cells in nude mice - characterisation of phenotype, cytokine secretion and tumour-associated antigens in BRITISH JOURNAL OF CANCER
  • 1996 Detektion Mamma-Karzinom-spezifiseher Proteine aus dem Serum xenotransplantierter Nacktmäuse mittels differentieller zweidimensionaler Elektrophorese in CHIRURGISCHES FORUM ’96 FUR EXPERIMENTELLE UND KLINISCHE FORSCHUNG
  • 1996-01 Relation of oestradiol-mediated growth stimulation with the expression of c-erbB-2 protein in xenotransplanted oestradiol-receptor-positive and -negative breast carcinomas in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 1994-09 Carboplatin-liposomes (CPL) in immunodeficient mice: Improved antitumor activity for breast carcinomas and stimulation of hematopoiesis in MEDICAL ONCOLOGY
  • 1994-01 Establishment and characteristics of two new human mammary carcinoma lines in nude mice with special reference to the estradiol receptor status and the importance of stroma forin vivo andin vitro growth in BREAST CANCER RESEARCH AND TREATMENT
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