Shyam K Sharan

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Shyam K



Publications in SciGraph latest 50 shown

  • 2018-12 BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage in NATURE COMMUNICATIONS
  • 2018-12 Clinical testing of BRCA1 and BRCA2: a worldwide snapshot of technological practices in NPJ GENOMIC MEDICINE
  • 2018-05 microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer in ONCOGENE
  • 2017-06-15 Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption in CELL DEATH & DISEASE
  • 2016-11 Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells in NATURE
  • 2016-08-08 Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies in NATURE COMMUNICATIONS
  • 2016-07 Replication fork stability confers chemoresistance in BRCA-deficient cells in NATURE
  • 2014-11 MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas in ONCOGENE
  • 2012-11 BRCA1 and MicroRNAs: Emerging networks and potential therapeutic targets in MOLECULES AND CELLS
  • 2012 Using Recombineering to Generate Point Mutations:galK-Based Positive–Negative Selection Method in GENE SYNTHESIS
  • 2012 Using Recombineering Technology to Create Genetically Engineered Mouse Models in GENETICALLY ENGINEERED MICE FOR CANCER RESEARCH
  • 2012 Using Recombineering to Generate Point Mutations: The Oligonucleotide-Based “Hit and Fix” Method in GENE SYNTHESIS
  • 2011-11 Erratum: Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155 in NATURE MEDICINE
  • 2011-10 Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155 in NATURE MEDICINE
  • 2010-06-15 Functional Analysis of Human BRCA2 Variants Using a Mouse Embryonic Stem Cell-Based Assay in CANCER SUSCEPTIBILITY
  • 2009-02 Recombineering: a homologous recombination-based method of genetic engineering in NATURE PROTOCOLS
  • 2008-08 Mouse embryonic stem cell–based functional assay to evaluate mutations in BRCA2 in NATURE MEDICINE
  • 2008-03 Thrombospondins: from structure to therapeutics in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2007-12 Resolving RAD51C function in late stages of homologous recombination in CELL DIVISION
  • 2005-07 Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models in NATURE CELL BIOLOGY
  • 2004-03-01 Bacterial Artificial Chromosome Engineering in BACTERIAL ARTIFICIAL CHROMOSOMES
  • 2004-03-01 BAC Rescue: A Tool for Functional Analysis of the Mouse Genome in BACTERIAL ARTIFICIAL CHROMOSOMES
  • 1998-10 Functional Characterization of BRCA1 and BRCA2: Clues from Their Interacting Proteins in JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
  • 1997-04 Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2 in NATURE
  • 1997-01 Identification and characterization of a microsatellite marker within murine Brca2 gene in MAMMALIAN GENOME
  • 1996-07 …and secreted tumour suppressors in NATURE GENETICS
  • 1993 Mutations Affecting Early Development in the Mouse in PREIMPLANTATION EMBRYO DEVELOPMENT
  • 1992-02 Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos in MAMMALIAN GENOME
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