Yu Tzu Tai

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Yu Tzu



Publications in SciGraph latest 50 shown

  • 2019-03 Preclinical assessment of an antibody–PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells in LEUKEMIA
  • 2019-02 APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications in LEUKEMIA
  • 2019-01 A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity in LEUKEMIA
  • 2018-12 Widespread intronic polyadenylation diversifies immune cell transcriptomes in NATURE COMMUNICATIONS
  • 2018-12 Long intergenic non-coding RNAs have an independent impact on survival in multiple myeloma in LEUKEMIA
  • 2018-12 Genomic patterns of progression in smoldering multiple myeloma in NATURE COMMUNICATIONS
  • 2018-09 Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors in LEUKEMIA
  • 2018-08 Genomic discovery and clonal tracking in multiple myeloma by cell-free DNA sequencing in LEUKEMIA
  • 2018-04 Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma in LEUKEMIA
  • 2018-03 Combination of a novel HDAC6 inhibitor ACY-241 and anti-PD-L1 antibody enhances anti-tumor immunity and cytotoxicity in multiple myeloma in LEUKEMIA
  • 2018-01 Nucleotide excision repair is a potential therapeutic target in multiple myeloma in LEUKEMIA
  • 2017-12 KDM6B modulates MAPK pathway mediating multiple myeloma cell growth and survival in LEUKEMIA
  • 2017-12 Interferon-alpha-based immunotherapies in the treatment of B cell-derived hematologic neoplasms in today’s treat-to-target era in EXPERIMENTAL HEMATOLOGY & ONCOLOGY
  • 2017-12 HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications in LEUKEMIA
  • 2017-10-05 Blockade of deubiquitylating enzyme Rpn11 triggers apoptosis in multiple myeloma cells and overcomes bortezomib resistance in ONCOGENE
  • 2017-10 A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo in LEUKEMIA
  • 2017-08 A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo in LEUKEMIA
  • 2017-03 Regulatory B cell-myeloma cell interaction confers immunosuppression and promotes their survival in the bone marrow milieu in BLOOD CANCER JOURNAL
  • 2016-09 Targeting proteasome ubiquitin receptor Rpn13 in multiple myeloma in LEUKEMIA
  • 2016-02 SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide in LEUKEMIA
  • 2016-01-05 The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival in NATURE COMMUNICATIONS
  • 2015-09 Class IIa HDAC inhibition enhances ER stress-mediated cell death in multiple myeloma in LEUKEMIA
  • 2015-06 The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells in NATURE MEDICINE
  • 2015-05 Rational combination treatment with histone deacetylase inhibitors and immunomodulatory drugs in multiple myeloma in BLOOD CANCER JOURNAL
  • 2015-02 Anti-tumor activities of selective HSP90α/β inhibitor, TAS-116, in combination with bortezomib in multiple myeloma in LEUKEMIA
  • 2015-02 Multiple myeloma patients with low proportion of circulating plasma cells had similar survival with primary plasma cell leukemia patients in ANNALS OF HEMATOLOGY
  • 2014-12 Heterogeneity of genomic evolution and mutational profiles in multiple myeloma in NATURE COMMUNICATIONS
  • 2014-03 Targeting homologous recombination and telomerase in Barrett’s adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth in ONCOGENE
  • 2014-01 CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications in LEUKEMIA
  • 2013 Antibody-Based Therapies in Multiple Myeloma in ADVANCES IN BIOLOGY AND THERAPY OF MULTIPLE MYELOMA
  • 2011-10 Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: a potential therapeutic application in multiple myeloma in LEUKEMIA
  • 2011-01 HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells in LEUKEMIA
  • 2009-05 Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer in NATURE GENETICS
  • 2008 Antibody and Other Immune-Based Therapies for Myeloma in MYELOMA THERAPY
  • 2008-01 A pivotal role for Mcl-1 in Bortezomib-induced apoptosis in ONCOGENE
  • 2006-05 Emerging Therapies for Multiple Myeloma in AMERICAN JOURNAL OF CANCER
  • 2004-11 p38 MAPK inhibition enhances PS-341 (bortezomib)-induced cytotoxicity against multiple myeloma cells in ONCOGENE
  • 2001-12 Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications in LEUKEMIA
  • 1998-11 BAD partly reverses paclitaxel resistance in human ovarian cancer cells in ONCOGENE
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