Reuben S Harris

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Reuben S



Publications in SciGraph latest 50 shown

  • 2019-12 A panel of eGFP reporters for single base editing by APOBEC-Cas9 editosome complexes in SCIENTIFIC REPORTS
  • 2019-01 Epstein–Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity in NATURE MICROBIOLOGY
  • 2018-12 Increasing Cas9-mediated homology-directed repair efficiency through covalent tethering of DNA repair template in COMMUNICATIONS BIOLOGY
  • 2018-12 Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease in NATURE COMMUNICATIONS
  • 2018-12 Natural APOBEC3C variants can elicit differential HIV-1 restriction activity in RETROVIROLOGY
  • 2017-12 Conformational Switch Regulates the DNA Cytosine Deaminase Activity of Human APOBEC3B in SCIENTIFIC REPORTS
  • 2017-12 Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity in SCIENTIFIC REPORTS
  • 2017-06-27 Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells in BRITISH JOURNAL OF CANCER
  • 2017-02 Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2016-12 DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer in GENOME BIOLOGY
  • 2016-09-21 The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis in NATURE COMMUNICATIONS
  • 2015-12 Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer in BREAST CANCER RESEARCH
  • 2015-12 APOBEC3G Interacts with ssDNA by Two Modes: AFM Studies in SCIENTIFIC REPORTS
  • 2015-06 Structure of the Vif-binding domain of the antiviral enzyme APOBEC3G in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-12 Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers in HORMONES AND CANCER
  • 2014-12 Small molecules that inhibit Vif-induced degradation of APOBEC3G in VIROLOGY JOURNAL
  • 2013-12 Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications in GENOME MEDICINE
  • 2013-12 APOBEC3 inhibits DEAD-END function to regulate microRNA activity in BMC MOLECULAR BIOLOGY
  • 2013-10-23 Corrigendum: APOBEC3B is an enzymatic source of mutation in breast cancer in NATURE
  • 2013-09 Evidence for APOBEC3B mutagenesis in multiple human cancers in NATURE GENETICS
  • 2013-02 APOBEC3B is an enzymatic source of mutation in breast cancer in NATURE
  • 2013 The APOBEC3 Family of Retroelement Restriction Factors in INTRINSIC IMMUNITY
  • 2012-01 Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection in NATURE
  • 2010-02 APOBEC3 proteins mediate the clearance of foreign DNA from human cells in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009 Host Factors that Restrict Retrovirus Replication in VIRAL GENOME REPLICATION
  • 2008-12 The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals in BMC MOLECULAR BIOLOGY
  • 2008-10 Enhancing immunity to HIV through APOBEC in NATURE BIOTECHNOLOGY
  • 2008-03 Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G in NATURE
  • 2006-05 Dancin' deaminase in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2004-11 Retroviral restriction by APOBEC proteins in NATURE REVIEWS IMMUNOLOGY
  • 2003-07 DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses in NATURE IMMUNOLOGY
  • 2002-07 AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification in NATURE
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