David Y Thomas

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David Y



Publications in SciGraph latest 50 shown

  • 2022-06-23 Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR in NATURE COMMUNICATIONS
  • 2022-03-17 The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway in SCIENTIFIC REPORTS
  • 2021-12-01 Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium in SCIENTIFIC REPORTS
  • 2018-07-30 A novel triple combination of pharmacological chaperones improves F508del-CFTR correction in SCIENTIFIC REPORTS
  • 2014-09-02 Chaperones in the Endoplasmic Reticulum (ER): Function and Interaction Network in THE MOLECULAR CHAPERONES INTERACTION NETWORKS IN PROTEIN FOLDING AND DEGRADATION
  • 2013-01-14 Compounds that correct F508del-CFTR trafficking can also correct other protein trafficking diseases: an in vitro study using cell lines in ORPHANET JOURNAL OF RARE DISEASES
  • 2007-07 1H, 13C and 15N resonance assignments of the bb′ domains of human protein disulfide isomerase in BIOMOLECULAR NMR ASSIGNMENTS
  • 2006-04-04 Predicting the subcellular localization of viral proteins within a mammalian host cell in VIROLOGY JOURNAL
  • 2004-01-04 The ER protein folding sensor UDP-glucose glycoprotein–glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2003 Calnexin, an ER Integral Membrane Chaperone in Health and Disease in CALRETICULIN
  • 2001 Lectins of the ER Quality Control Machinery in MAMMALIAN CARBOHYDRATE RECOGNITION SYSTEMS
  • 1998 The Role of the Lectin Calnexin in Conformation Independent Binding to N-Linked Glycoproteins and Quality Control in GLYCOIMMUNOLOGY 2
  • 1998-01 Interaction of a G-protein β-subunit with a conserved sequence in Ste20/PAK family protein kinases in NATURE
  • 1996-10 Genetic interactions indicate a role for Mdg1p and the SH3 domain protein Bem1p in linking the G-protein mediated yeast pheromone signalling pathway to regulators of cell polarity in MOLECULAR GENETICS AND GENOMICS
  • 1996-01-22 PCR-Assisted Mutagenesis for Site-Directed Insertion/Deletion of Large DNA Segments in IN VITRO MUTAGENESIS PROTOCOLS
  • 1996 The Roles of Calnexin and Calreticulin as Endoplasmic Reticulum Molecular Chaperones in CALRETICULIN
  • 1995-11 Constitutive activation of the Saccharomyces cerevislae mating response pathway by a MAP kinase kinase from Candida albicans in MOLECULAR GENETICS AND GENOMICS
  • 1994-07 MPSA abstracts in THE PROTEIN JOURNAL
  • 1993-11 Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Farl in MOLECULAR GENETICS AND GENOMICS
  • 1993-08 Association of folding intermediates of glycoproteins with calnexin during protein maturation in NATURE
  • 1991-07 Ubiquitin gene expression: response to environmental changes in CURRENT GENETICS
  • 1991-05 Expression in yeast of a cDNA copy of the K2 killer toxin gene in MOLECULAR GENETICS AND GENOMICS
  • 1990-08 An effective transformation method for Hansenula polymorpha in CURRENT GENETICS
  • 1990-03 The kalilo senescence plasmid of Neurospora intermedia has covalently-linked 5′ terminal proteins in CURRENT GENETICS
  • 1990-02 Genetic and molecular approaches to synthesis and action of the yeast killer toxin in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 1989-09 Cloning and characterization of the SKI3 gene of Saccharomyces cerevisiae demonstrates allelism to SKI5 in CURRENT GENETICS
  • 1988-09 Expression of MFα1 in MATa cells supersensitive to α-factor leads to self-arrest in MOLECULAR GENETICS AND GENOMICS
  • 1988 Expression of Hepatitis B Virus Surface Antigen Gene in Mammalian, Yeast, and Insect Cells in NEW VACCINES AND CHEMOTHERAPY
  • 1981-02 Molecular cloning and organization of two leghaemoglobin genomic sequences of soybean in NATURE
  • 1980-07 Transformation of Saccharomyces cerevisiae with plasmids containing fragments of yeast 2 μ DNA and a suppressor tRNA gene in CURRENT GENETICS
  • 1977-01 Synthesis of cytochromec oxidase polypeptides in anEscherichia coli cell-free system directed bySaccharomyces cerevisiae mitochondrial DNA in MOLECULAR GENETICS AND GENOMICS
  • 1971-10 Products of Mitochondrial Protein Synthesis in Yeast in NATURE
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