Michel C Nussenzweig

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Michel C



Publications in SciGraph latest 50 shown

  • 2018-12 Structural characterization of a highly-potent V3-glycan broadly neutralizing antibody bound to natively-glycosylated HIV-1 envelope in NATURE COMMUNICATIONS
  • 2018-11 Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals in NATURE MEDICINE
  • 2018-09 Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency in NATURE IMMUNOLOGY
  • 2018-09 Combination therapy with anti-HIV-1 antibodies maintains viral suppression in NATURE
  • 2018-05 A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection in NATURE MEDICINE
  • 2018-05 Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation in NATURE MEDICINE
  • 2017-03-13 Early antibody therapy can induce long-lasting immunity to SHIV in NATURE
  • 2017-02 Antibody 10-1074 suppresses viremia in HIV-1-infected individuals in NATURE MEDICINE
  • 2016-10 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2016-09-15 Sequencing and cloning of antigen-specific antibodies from mouse memory B cells in NATURE PROTOCOLS
  • 2016-06-22 HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption in NATURE
  • 2016-05 A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges in NATURE
  • 2016-03-23 Corrigendum: Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 in NATURE
  • 2016-02-24 Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice in NATURE COMMUNICATIONS
  • 2015-12 Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike in NATURE COMMUNICATIONS
  • 2015-09 Defining human dendritic cell progenitors by multiparametric flow cytometry in NATURE PROTOCOLS
  • 2015-08-26 Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching in NATURE
  • 2015-06 Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 in NATURE
  • 2015-03 AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges in NATURE
  • 2015-01-06 Immunology: Fifty years of B lymphocytes in NATURE
  • 2014-12 A robust pipeline for rapid production of versatile nanobody repertoires in NATURE METHODS
  • 2014-05 Clonal selection in the germinal centre by regulated proliferation and hypermutation in NATURE
  • 2014-02-09 MONDAY PUSHLIVE TEST L-Myc expression by dendritic cells is required for optimal T-cell priming in NATURE
  • 2014-02-09 L-Myc expression by dendritic cells is required for optimal T-cell priming in NATURE
  • 2013-11 Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia in NATURE
  • 2013-11 Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys in NATURE
  • 2013-09 Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens in NATURE IMMUNOLOGY
  • 2013-06 Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection in NATURE MEDICINE
  • 2013-04-03 HIV: Roadmaps to a vaccine in NATURE
  • 2012-12 HIV therapy by a combination of broadly neutralizing antibodies in humanized mice in NATURE
  • 2012-11 The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry in NATURE IMMUNOLOGY
  • 2012-09 Structural basis for germline gene usage of a potent class of antibodies targeting the CD4 binding site of HIV-1 gp120 in RETROVIROLOGY
  • 2012-05 Polyreactive antibodies in adaptive immune responses to viruses in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2012-02-07 DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes in NATURE
  • 2011-10 Ralph Steinman <i>(1943–2011)</i> in NATURE
  • 2011-01 Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes in NATURE IMMUNOLOGY
  • 2010-09 Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation in NATURE
  • 2009-04 Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals in NATURE
  • 2008-11 53BP1 facilitates long-range DNA end-joining during V(D)J recombination in NATURE
  • 2008-06 The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues in NATURE IMMUNOLOGY
  • 2008-01 AID is required for germinal center–derived lymphomagenesis in NATURE GENETICS
  • 2007-12 Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly in ONCOGENE
  • 2007-11 Corrigendum: Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes in NATURE IMMUNOLOGY
  • 2007-08 Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes in NATURE IMMUNOLOGY
  • 2007-08 Antigen receptor diversification and chromosome translocations in NATURE IMMUNOLOGY
  • 2007-07 Chromatin dynamics and the preservation of genetic information in NATURE
  • 2007-06 Origin of dendritic cells in peripheral lymphoid organs of mice in NATURE IMMUNOLOGY
  • 2007-04 Killing some to make way for others in NATURE IMMUNOLOGY
  • 2007-03 In vivo imaging of germinal centres reveals a dynamic open structure in NATURE
  • 2006-12 The circumsporozoite protein is an immunodominant protective antigen in irradiated sporozoites in NATURE
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