Matthew Bogyo

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Publications in SciGraph latest 50 shown

  • 2018-12 Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes in NATURE COMMUNICATIONS
  • 2018-06 Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP) in NATURE CHEMICAL BIOLOGY
  • 2017-12 The lysosomal protein cathepsin L is a progranulin protease in MOLECULAR NEURODEGENERATION
  • 2017-10 Fluorescence Imaging for Cancer Screening and Surveillance in MOLECULAR IMAGING AND BIOLOGY
  • 2017-08 Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection in NATURE MICROBIOLOGY
  • 2017 Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe in ACTIVITY-BASED PROTEOMICS
  • 2016-12 A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer in MOLECULAR IMAGING AND BIOLOGY
  • 2016-10 An in vivo multiplexed small-molecule screening platform in NATURE METHODS
  • 2016-04 Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes in SCIENTIFIC REPORTS
  • 2016-02 Structure- and function-based design of Plasmodium-selective proteasome inhibitors in NATURE
  • 2016 Detection of Active Caspases During Apoptosis Using Fluorescent Activity-Based Probes in PROGRAMMED CELL DEATH
  • 2016-01 Labeling of active proteases in fresh-frozen tissues by topical application of quenched activity-based probes in NATURE PROTOCOLS
  • 2014-11 Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice in CELL DEATH & DIFFERENTIATION
  • 2014-10 Microscopic Detection of Quenched Activity-Based Optical Imaging Probes Using an Antibody Detection System: Localizing Protease Activity in MOLECULAR IMAGING AND BIOLOGY
  • 2013-10 Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion in NATURE CHEMICAL BIOLOGY
  • 2012-09 Caspase-1 activity is required to bypass macrophage apoptosis upon Salmonella infection in NATURE CHEMICAL BIOLOGY
  • 2012-05 Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes in APOPTOSIS
  • 2012-01 New approaches for dissecting protease functions to improve probe development and drug discovery in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2011-12 Cathepsin B trafficking in thyroid carcinoma cells in THYROID RESEARCH
  • 2011-09 Ferri-liposomes as an MRI-visible drug-delivery system for targeting tumours and their microenvironment in NATURE NANOTECHNOLOGY
  • 2011-03 Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-08 Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes in NATURE MEDICINE
  • 2009-07 Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin in NATURE CHEMICAL BIOLOGY
  • 2009-03 Cathepsin X-mediated β2 integrin activation results in nanotube outgrowth in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2008-03 Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum in NATURE CHEMICAL BIOLOGY
  • 2008 Activity-Based Imaging and Biochemical Profiling Tools for Analysis of the Cancer Degradome in THE CANCER DEGRADOME
  • 2007-10 Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes in NATURE CHEMICAL BIOLOGY
  • 2007-04 Specificity of aza-peptide electrophile activity-based probes of caspases in CELL DEATH & DIFFERENTIATION
  • 2006-12 Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity in CELL RESEARCH
  • 2005-09 Dynamic imaging of protease activity with fluorescently quenched activity-based probes in NATURE CHEMICAL BIOLOGY
  • 2005-06 Activity-based probes that target diverse cysteine protease families in NATURE CHEMICAL BIOLOGY
  • 2005 Chemical Proteomics in Drug Development in THE ONCOGENOMICS HANDBOOK
  • 2004-12 Activity-Based Protein Profiling in AMERICAN JOURNAL OF PHARMACOGENOMICS
  • 2003-08 Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity in CELL DEATH & DIFFERENTIATION
  • 2002 Peptide vinyl sulfones: Inhibitors and active site probes for the study of proteasome function in vivo in PEPTIDES FRONTIERS OF PEPTIDE SCIENCE
  • 2002 Proteasome Inhibitors: Complex Tools for a Complex Enzyme in THE PROTEASOME — UBIQUITIN PROTEIN DEGRADATION PATHWAY
  • 1998-12 Antigen presentation: A protease draws first blood in NATURE
  • 1998-04 A proteolytic system that compensates for loss of proteasome function in NATURE
  • 1996-12 Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction in NATURE
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