Dirk G Brockstedt

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Dirk G



Publications in SciGraph latest 50 shown

  • 2015-12 Phase I study of safety and immunogenicity of ADU-623, a live-attenuated listeria monocytogenes vaccine (ΔactA/ΔinlB) expressing EGFRVIII and NY-ESO-1, in patients with who grade III/IV astrocytomas in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Randomized Phase II study of the safety, efficacy and immune response of GVAX pancreas (with cyclophosphamide) and CRS-207 with or without nivolumab in patients with previously treated metastatic pancreatic adenocarcinoma (STELLAR) in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Anti-mesothelin vaccine CRS-207 with or without low-dose cyclophosphamide plus chemotherapy as front-line treatment for malignant pleural mesothelioma (MPM) in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Long term survivors and immune biomarker analysis of Phase IIa, randomized study of GVAX pancreas and crs-207 immunotherapy in patients with metastatic pancreatic cancer in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 A Phase IIb, randomized, multicenter study of the efficacy of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously-treated metastatic pancreatic adenocarcinoma (eclipse study) in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Development of mutome-specific personalized vaccines for pancreatic cancer in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Clinical experience with live-attenuated, double-deleted (LADD) listeria monocytogenes targeting mesothelin-expressing tumors in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2012-12 A novel series of conferences tackling the hurdles confronting the translation of novel cancer immunotherapies in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2012-07 Tumor-Associated Antigen Expressing Listeria monocytogenes Induces Effective Primary and Memory T-Cell Responses Against Hepatic Colorectal Cancer Metastases in ANNALS OF SURGICAL ONCOLOGY
  • 2007-10-17 Simultaneous detection of murine antigen-specific intracellular cytokines and CD107a/CD107b by flow cytometry in PROTOCOL EXCHANGE
  • 2006-02 Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity in NATURE MEDICINE
  • 2005-08 Killed but metabolically active microbes: a new vaccine paradigm for eliciting effector T-cell responses and protective immunity in NATURE MEDICINE
  • 1999-06 Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients in NATURE MEDICINE
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